eprintid: 10173026
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/17/30/26
datestamp: 2023-07-06 14:00:48
lastmod: 2023-07-06 14:00:48
status_changed: 2023-07-06 14:00:48
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Groning, F
creators_name: Jones, MEH
creators_name: Curtis, N
creators_name: Herrel, A
creators_name: O'Higgins, P
creators_name: Evans, SE
creators_name: Fagan, MJ
title: The importance of accurate muscle modelling for biomechanical analyses: a case study with a lizard skull
ispublished: pub
divisions: UCL
divisions: B02
divisions: C08
divisions: D09
divisions: F96
keywords: bite force, multibody dynamics analysis, skull, feeding, validation, Tupinambis
note: © 2013 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.
abstract: Computer-based simulation techniques such as multi-body dynamics analysis are becoming increasingly popular in the field of skull mechanics. Multi-body models can be used for studying the relationships between skull architecture, muscle morphology and feeding performance. However, to be confident in the modelling results, models need to be validated against experimental data, and the effects of uncertainties or inaccuracies in the chosen model attributes need to be assessed with sensitivity analyses. Here, we compare the bite forces predicted by a multi-body model of a lizard (Tupinambis merianae) with in vivo measurements, using anatomical data collected from the same specimen. This subject-specific model predicts bite forces that are very close to the in vivo measurements and also shows a consistent increase in bite force as the bite position is moved posteriorly on the jaw. However, the model is very sensitive to changes in muscle attributes such as fibre length, intrinsic muscle strength and force orientation, with bite force predictions varying considerably when these three variables are altered. We conclude that accurate muscle measurements are crucial to building realistic multi-body models and that subject-specific data should be used whenever possible.
date: 2013-07-06
date_type: published
publisher: Royal Society
official_url: https://doi.org/10.1098/rsif.2013.0216
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 869706
doi: 10.1098/rsif.2013.0216
medium: Electronic-Print
pii: rsif.2013.0216
lyricists_name: Evans, Susan
lyricists_name: Jones, Marc
lyricists_id: SEEVA33
lyricists_id: MEHJO63
actors_name: Evans, Susan
actors_name: Mustafa, Adelat
actors_id: SEEVA33
actors_id: AMUST21
actors_role: owner
actors_role: impersonator
funding_acknowledgements: BB/E007465 [BBSRC]; BB/E009204 [BBSRC]; BB/E007813 [BBSRC]; BB/H011668/1 [Biotechnology and Biological Sciences Research Council]; BB/H011390/1 [Biotechnology and Biological Sciences Research Council]; BB/H011854/1 [Biotechnology and Biological Sciences Research Council]; BB/H011854/1 [BBSRC]; BB/H011668/1 [BBSRC]; BB/H011390/1 [BBSRC]
full_text_status: public
publication: Journal of The Royal Society Interface
volume: 10
number: 84
article_number: 20130216
place_of_pub: London UK
event_location: England
issn: 1742-5662
citation:        Groning, F;    Jones, MEH;    Curtis, N;    Herrel, A;    O'Higgins, P;    Evans, SE;    Fagan, MJ;      (2013)    The importance of accurate muscle modelling for biomechanical analyses: a case study with a lizard skull.                   Journal of The Royal Society Interface , 10  (84)    , Article 20130216.  10.1098/rsif.2013.0216 <https://doi.org/10.1098/rsif.2013.0216>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10173026/1/Evans_2013_The%20Importance%20of%20Accurate%20Muscle%20modelling%20Interface.pdf