<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10172945> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/title> "Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applications"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/abstract> "Although sex and gender are recognized as major determinants of health and immunity, their role israrely considered in clinical practice and public health. We identified six bottlenecks preventing theinclusion of sex and gender considerations from basic science to clinical practice, precision medicineand public health policies. (i) A terminology-related bottleneck, linked to the definitions of sex andgender themselves, and the lack of consensus on how to evaluate gender. (ii) A data-relatedbottleneck, due to gaps in sex-disaggregated data, data on trans/non-binary people and genderidentity. (iii) A translational bottleneck, limited by animal models and the underrepresentation ofgender minorities in biomedical studies. (iv) A statistical bottleneck, with inappropriate statisticalanalyses and results interpretation. (v) An ethical bottleneck posed by the underrepresentation ofpregnant people and gender minorities in clinical studies. (vi) A structural bottleneck, as systemicbias and discriminations affect not only academic research but also decision makers. We specifyguidelines for researchers, scientific journals, funding agencies and academic institutions to addressthese bottlenecks. Following such guidelines will support the development of more efficient andequitable care strategies for all."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/date> "2023-07" .
<https://discovery.ucl.ac.uk/id/document/1619669> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/volume> "10" .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/issue> "7" .
<https://discovery.ucl.ac.uk/id/org/ext-7f542cf339bda9ab39e7035b432a38e4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery.ucl.ac.uk/id/org/ext-7f542cf339bda9ab39e7035b432a38e4> <http://xmlns.com/foaf/0.1/name> "The Royal Society"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/publisher> <https://discovery.ucl.ac.uk/id/org/ext-7f542cf339bda9ab39e7035b432a38e4> .
<https://discovery.ucl.ac.uk/id/publication/ext-6bacc5aa23c86db992b9958fd6f370d2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-6bacc5aa23c86db992b9958fd6f370d2> <http://xmlns.com/foaf/0.1/name> "Royal Society Open Science"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-6bacc5aa23c86db992b9958fd6f370d2> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d63cae8685952348a9aae3319e4823c6> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-d63cae8685952348a9aae3319e4823c6> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-1f09d3320728cf60e6390a77de29ceff> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-1f09d3320728cf60e6390a77de29ceff> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a8e8fd07ef27834a86831b72a82b3de9> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-a8e8fd07ef27834a86831b72a82b3de9> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-aec334620ebd627d8f51818e330504c1> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-aec334620ebd627d8f51818e330504c1> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-01684b9fb82326305ae7d54c8e80ebbc> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-01684b9fb82326305ae7d54c8e80ebbc> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4c799a627e12578ba7a3f6afcb8695f2> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-4c799a627e12578ba7a3f6afcb8695f2> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b1b73f1ac4ae74cc1c31252aa341e3af> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-b1b73f1ac4ae74cc1c31252aa341e3af> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-26cad86912fcf5071a71301c11dd6485> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-26cad86912fcf5071a71301c11dd6485> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-bbdbedbc7e426d6ef31c574f4d6cdd32> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-bbdbedbc7e426d6ef31c574f4d6cdd32> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-8a536dec5266f465bc2b62168b117867> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-8a536dec5266f465bc2b62168b117867> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-5f543647b930238dd6264d5f9c39fdb7> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-5f543647b930238dd6264d5f9c39fdb7> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3e89014170f9111ed2b7c665223d74a6> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-3e89014170f9111ed2b7c665223d74a6> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f25093627744c09465d5cc1b8b35afc6> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-f25093627744c09465d5cc1b8b35afc6> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a60199c4503921b90fceaad9ecff7c06> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_14> <https://discovery.ucl.ac.uk/id/person/ext-a60199c4503921b90fceaad9ecff7c06> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-82f47ce27c3693496a0c20d930cb2206> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_15> <https://discovery.ucl.ac.uk/id/person/ext-82f47ce27c3693496a0c20d930cb2206> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-27e83bc16d44152b02851d2ed4b78f76> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_16> <https://discovery.ucl.ac.uk/id/person/ext-27e83bc16d44152b02851d2ed4b78f76> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b8dc9447b9d961983bb6bbb1d9f0cb4a> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_17> <https://discovery.ucl.ac.uk/id/person/ext-b8dc9447b9d961983bb6bbb1d9f0cb4a> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-352d583c3915704febf935f5c644399d> .
<https://discovery.ucl.ac.uk/id/eprint/10172945> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10172945#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10172945#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_18> <https://discovery.ucl.ac.uk/id/person/ext-352d583c3915704febf935f5c644399d> .
<https://discovery.ucl.ac.uk/id/person/ext-3e89014170f9111ed2b7c665223d74a6> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-3e89014170f9111ed2b7c665223d74a6> <http://xmlns.com/foaf/0.1/givenName> "Melanie"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3e89014170f9111ed2b7c665223d74a6> <http://xmlns.com/foaf/0.1/familyName> "Schirmer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3e89014170f9111ed2b7c665223d74a6> <http://xmlns.com/foaf/0.1/name> "Melanie Schirmer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1f09d3320728cf60e6390a77de29ceff> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-1f09d3320728cf60e6390a77de29ceff> <http://xmlns.com/foaf/0.1/givenName> "Chloé"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1f09d3320728cf60e6390a77de29ceff> <http://xmlns.com/foaf/0.1/familyName> "Pasin"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1f09d3320728cf60e6390a77de29ceff> <http://xmlns.com/foaf/0.1/name> "Chloé Pasin"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8a536dec5266f465bc2b62168b117867> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-8a536dec5266f465bc2b62168b117867> <http://xmlns.com/foaf/0.1/givenName> "Maria"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8a536dec5266f465bc2b62168b117867> <http://xmlns.com/foaf/0.1/familyName> "Pujantell"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8a536dec5266f465bc2b62168b117867> <http://xmlns.com/foaf/0.1/name> "Maria Pujantell"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-352d583c3915704febf935f5c644399d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-352d583c3915704febf935f5c644399d> <http://xmlns.com/foaf/0.1/givenName> "Sebastian"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-352d583c3915704febf935f5c644399d> <http://xmlns.com/foaf/0.1/familyName> "Bonhoeffer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-352d583c3915704febf935f5c644399d> <http://xmlns.com/foaf/0.1/name> "Sebastian Bonhoeffer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4c799a627e12578ba7a3f6afcb8695f2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-4c799a627e12578ba7a3f6afcb8695f2> <http://xmlns.com/foaf/0.1/givenName> "Enriqueta"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4c799a627e12578ba7a3f6afcb8695f2> <http://xmlns.com/foaf/0.1/familyName> "Vallejo-Yagüe"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4c799a627e12578ba7a3f6afcb8695f2> <http://xmlns.com/foaf/0.1/name> "Enriqueta Vallejo-Yagüe"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-bbdbedbc7e426d6ef31c574f4d6cdd32> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-bbdbedbc7e426d6ef31c574f4d6cdd32> <http://xmlns.com/foaf/0.1/givenName> "Nadia"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-bbdbedbc7e426d6ef31c574f4d6cdd32> <http://xmlns.com/foaf/0.1/familyName> "Neuner-Jehle"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-bbdbedbc7e426d6ef31c574f4d6cdd32> <http://xmlns.com/foaf/0.1/name> "Nadia Neuner-Jehle"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-26cad86912fcf5071a71301c11dd6485> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-26cad86912fcf5071a71301c11dd6485> <http://xmlns.com/foaf/0.1/givenName> "Ulrika"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-26cad86912fcf5071a71301c11dd6485> <http://xmlns.com/foaf/0.1/familyName> "Islander"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-26cad86912fcf5071a71301c11dd6485> <http://xmlns.com/foaf/0.1/name> "Ulrika Islander"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-27e83bc16d44152b02851d2ed4b78f76> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-27e83bc16d44152b02851d2ed4b78f76> <http://xmlns.com/foaf/0.1/givenName> "Karoline"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-27e83bc16d44152b02851d2ed4b78f76> <http://xmlns.com/foaf/0.1/familyName> "Aebi-Popp"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-27e83bc16d44152b02851d2ed4b78f76> <http://xmlns.com/foaf/0.1/name> "Karoline Aebi-Popp"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-01684b9fb82326305ae7d54c8e80ebbc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
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<https://discovery.ucl.ac.uk/id/person/ext-b8dc9447b9d961983bb6bbb1d9f0cb4a> <http://xmlns.com/foaf/0.1/givenName> "Roger D"^^<http://www.w3.org/2001/XMLSchema#string> .
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