eprintid: 10172395 rev_number: 9 eprint_status: archive userid: 699 dir: disk0/10/17/23/95 datestamp: 2023-06-23 13:47:06 lastmod: 2023-06-27 07:07:15 status_changed: 2023-06-23 13:47:06 type: proceedings_section metadata_visibility: show sword_depositor: 699 creators_name: Emes, MR creators_name: Smith, A creators_name: Hughes, I title: Internal invention, external development ispublished: pub divisions: UCL divisions: B04 divisions: C06 divisions: F63 note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: The success of GlaxoSmithKline’s (GSK’s) business relies on the continual identification of differentiated and innovative drugs that can be protected under patent for twenty years. Advances that can increase the number of new drugs successfully introduced to the marketplace or that can reduce the amount of time spent in the product pipeline (between identifying a potential new drug and releasing it in the marketplace) will be of great value to GSK. One way to increase the throughput of successful drugs is to increase the number of potential target compounds that enter the product pipeline. GSK has achieved this by developing a ‘high-throughput chemistry facility’, which uses advanced automation systems to perform tasks that would previously have been performed manually by chemists; this facility now plays a key role in the drug discovery process. During a three-year research project, and with a primary focus on this new facility, University College London has investigated GSK’s relationship with its suppliers of automation instrumentation. We have discovered that GSK often provides the ideas for new systems to its suppliers, who then develop the products commercially and sell them in the marketplace. Interestingly, so as to encourage continuity of the supply chain, GSK generally allows its suppliers to sell instrumentation produced from GSK ideas to GSK’s competitors. This paper is a case study investigating how GSK works with suppliers of equipment essential for its Research and Development process, and why this structure proves mutually beneficial. date: 2005 date_type: published publisher: RADMA official_url: https://radma.net/conferences/previous-radma-conferences/ oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 338488 lyricists_name: Emes, Michael lyricists_name: Smith, Alan lyricists_id: MREME29 lyricists_id: ASMIT51 actors_name: Jayawardana, Anusha actors_id: AJAYA51 actors_role: owner full_text_status: public pres_type: paper place_of_pub: Pisa, Italy event_title: R&D Management Conference 2005 event_location: Pisa, Italy event_dates: 6 Jul 2005 - 8 Jul 2005 book_title: Proceedings of the R&D Management Conference 2005: Organising R&D activities: a Balancing Act citation: Emes, MR; Smith, A; Hughes, I; (2005) Internal invention, external development. In: Proceedings of the R&D Management Conference 2005: Organising R&D activities: a Balancing Act. RADMA: Pisa, Italy. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10172395/1/Emes_EmesHughesSmith_InternalInventionExternalDevelopment.pdf