?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Internal+invention%2C+external+development&rft.creator=Emes%2C+MR&rft.creator=Smith%2C+A&rft.creator=Hughes%2C+I&rft.description=The+success+of+GlaxoSmithKline%E2%80%99s+(GSK%E2%80%99s)+business+relies+on+the+continual+identification+of+differentiated+and+innovative+drugs+that+can+be+protected+under+patent+for+twenty+years.+Advances+that+can+increase+the+number+of+new+drugs+successfully+introduced+to+the+marketplace+or+that+can+reduce+the+amount+of+time+spent+in+the+product+pipeline+(between+identifying+a+potential+new+drug+and+releasing+it+in+the+marketplace)+will+be+of+great+value+to+GSK.+One+way+to+increase+the+throughput+of+successful+drugs+is+to+increase+the+number+of+potential+target+compounds+that+enter+the+product+pipeline.+GSK+has+achieved+this+by+developing+a+%E2%80%98high-throughput+chemistry+facility%E2%80%99%2C+which+uses+advanced+automation+systems+to+perform+tasks+that+would+previously+have+been+performed+manually+by+chemists%3B+this+facility+now+plays+a+key+role+in+the+drug+discovery+process.+%09%09During+a+three-year+research+project%2C+and+with+a+primary+focus+on+this+new+facility%2C+University+College+London+has+investigated+GSK%E2%80%99s+relationship+with+its+suppliers+of+automation+instrumentation.+We+have+discovered+that+GSK+often+provides+the+ideas+for+new+systems+to+its+suppliers%2C+who+then+develop+the+products+commercially+and+sell+them+in+the+marketplace.+Interestingly%2C+so+as+to+encourage+continuity+of+the+supply+chain%2C+GSK+generally+allows+its+suppliers+to+sell+instrumentation+produced+from+GSK+ideas+to+GSK%E2%80%99s+competitors.+This+paper+is+a+case+study+investigating+how+GSK+works+with+suppliers+of+equipment+essential+for+its+Research+and+Development+process%2C+and+why+this+structure+proves+mutually+beneficial.&rft.publisher=RADMA&rft.date=2005&rft.type=Proceedings+paper&rft.language=eng&rft.source=+++++In%3A++Proceedings+of+the+R%26D+Management+Conference+2005%3A+Organising+R%26D+activities%3A+a+Balancing+Act.++++RADMA%3A+Pisa%2C+Italy.+(2005)+++++&rft.format=text&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F10172395%2F1%2FEmes_EmesHughesSmith_InternalInventionExternalDevelopment.pdf&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F10172395%2F&rft.rights=open