eprintid: 10166862
rev_number: 7
eprint_status: archive
userid: 699
dir: disk0/10/16/68/62
datestamp: 2023-03-22 10:03:14
lastmod: 2023-03-22 10:03:14
status_changed: 2023-03-22 10:03:14
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Delvi, Afraa
creators_name: Wilson, Claire A
creators_name: Jasani, Iman
creators_name: Guliani, Joshana
creators_name: Rao, Ranga
creators_name: Seneviratne, Gertrude
creators_name: Rogers, Jonathan P
title: Catatonia in the peripartum: A cohort study using electronic health records
ispublished: inpress
divisions: UCL
divisions: B02
divisions: C07
divisions: D79
divisions: FH8
keywords: Catatonia, Electroconvulsive therapy, Perinatal, Peripartum, Postnatal, Postpartum
note: © 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
abstract: BACKGROUND: Due to limited existing literature available on the presentation and treatment of catatonia in the peripartum, this retrospective descriptive cohort study aimed to examine demographic data, catatonic features, diagnoses pre- and post-catatonic episodes, treatment and the presence of obstetric complications. METHODS: Individuals with catatonia were identified in a previous study using anonymised electronic healthcare records from a large mental health trust in South-East London. The presence of features from the Bush-Francis Catatonia Screening Instrument was coded by the investigators and longitudinal data were extracted from structured fields and free text. 

RESULTS: 21 individuals were identified from the larger cohort, each of whom experienced one episode of catatonia in the postpartum period, and all had had an inpatient psychiatric admission. 13 patients (62 %) presented after their first pregnancy and 12 (57 %) experienced obstetric complications. 11 (53 %) attempted breastfeeding and 10 (48 %) received a diagnosis of a depressive disorder following the episode of catatonia. The majority presented with immobility or stupor, mutism, staring and withdrawal. All were treated with antipsychotics and 19 (90 %) received benzodiazepines. 

CONCLUSIONS: This study suggests that signs and symptoms of catatonia during the peripartum are similar to other catatonic presentations. However, the postpartum may be a period of high risk for catatonia and obstetric factors, such as birth complications, may be relevant.
date: 2023-03-03
date_type: published
publisher: Elsevier BV
official_url: https://doi.org/10.1016/j.schres.2023.02.022
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 2011128
doi: 10.1016/j.schres.2023.02.022
medium: Print-Electronic
pii: S0920-9964(23)00074-9
lyricists_name: Rogers, Jonathan
lyricists_id: JPROG48
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
full_text_status: public
publication: Schizophrenia Research
event_location: Netherlands
issn: 0920-9964
citation:        Delvi, Afraa;    Wilson, Claire A;    Jasani, Iman;    Guliani, Joshana;    Rao, Ranga;    Seneviratne, Gertrude;    Rogers, Jonathan P;      (2023)    Catatonia in the peripartum: A cohort study using electronic health records.                   Schizophrenia Research        10.1016/j.schres.2023.02.022 <https://doi.org/10.1016/j.schres.2023.02.022>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10166862/1/1-s2.0-S0920996423000749-main.pdf