eprintid: 10166862 rev_number: 7 eprint_status: archive userid: 699 dir: disk0/10/16/68/62 datestamp: 2023-03-22 10:03:14 lastmod: 2023-03-22 10:03:14 status_changed: 2023-03-22 10:03:14 type: article metadata_visibility: show sword_depositor: 699 creators_name: Delvi, Afraa creators_name: Wilson, Claire A creators_name: Jasani, Iman creators_name: Guliani, Joshana creators_name: Rao, Ranga creators_name: Seneviratne, Gertrude creators_name: Rogers, Jonathan P title: Catatonia in the peripartum: A cohort study using electronic health records ispublished: inpress divisions: UCL divisions: B02 divisions: C07 divisions: D79 divisions: FH8 keywords: Catatonia, Electroconvulsive therapy, Perinatal, Peripartum, Postnatal, Postpartum note: © 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/) abstract: BACKGROUND: Due to limited existing literature available on the presentation and treatment of catatonia in the peripartum, this retrospective descriptive cohort study aimed to examine demographic data, catatonic features, diagnoses pre- and post-catatonic episodes, treatment and the presence of obstetric complications. METHODS: Individuals with catatonia were identified in a previous study using anonymised electronic healthcare records from a large mental health trust in South-East London. The presence of features from the Bush-Francis Catatonia Screening Instrument was coded by the investigators and longitudinal data were extracted from structured fields and free text. RESULTS: 21 individuals were identified from the larger cohort, each of whom experienced one episode of catatonia in the postpartum period, and all had had an inpatient psychiatric admission. 13 patients (62 %) presented after their first pregnancy and 12 (57 %) experienced obstetric complications. 11 (53 %) attempted breastfeeding and 10 (48 %) received a diagnosis of a depressive disorder following the episode of catatonia. The majority presented with immobility or stupor, mutism, staring and withdrawal. All were treated with antipsychotics and 19 (90 %) received benzodiazepines. CONCLUSIONS: This study suggests that signs and symptoms of catatonia during the peripartum are similar to other catatonic presentations. However, the postpartum may be a period of high risk for catatonia and obstetric factors, such as birth complications, may be relevant. date: 2023-03-03 date_type: published publisher: Elsevier BV official_url: https://doi.org/10.1016/j.schres.2023.02.022 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 2011128 doi: 10.1016/j.schres.2023.02.022 medium: Print-Electronic pii: S0920-9964(23)00074-9 lyricists_name: Rogers, Jonathan lyricists_id: JPROG48 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner full_text_status: public publication: Schizophrenia Research event_location: Netherlands issn: 0920-9964 citation: Delvi, Afraa; Wilson, Claire A; Jasani, Iman; Guliani, Joshana; Rao, Ranga; Seneviratne, Gertrude; Rogers, Jonathan P; (2023) Catatonia in the peripartum: A cohort study using electronic health records. Schizophrenia Research 10.1016/j.schres.2023.02.022 <https://doi.org/10.1016/j.schres.2023.02.022>. (In press). Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10166862/1/1-s2.0-S0920996423000749-main.pdf