TY  - JOUR
TI  - Admixture of evolutionary rates across a butterfly hybrid zone
PB  - eLIFE SCIENCES PUBL LTD
Y1  - 2022/06/15/
N1  - Copyright © et al. This
article is distributed under the
terms of the Creative Commons
Attribution License, which
permits unrestricted use and
redistribution provided that the
original author and source are
credited.
ID  - discovery10165520
JF  - eLife
SN  - 2050-084X
UR  - https://doi.org/10.7554/eLife.78135
A1  - Xiong, Tianzhu
A1  - Li, Xueyan
A1  - Yago, Masaya
A1  - Mallet, James
KW  - Science & Technology
KW  -  Life Sciences & Biomedicine
KW  -  Biology
KW  -  Life Sciences & Biomedicine - Other Topics
KW  -  hybridization
KW  -  reproductive isolation
KW  -  molecular clock
KW  -  gene flow
KW  -  Other
KW  -  DIVERGENT SELECTION
KW  -  MUTATION-RATE
KW  -  GENE FLOW
KW  -  HYBRIDIZATION
KW  -  POPULATION
KW  -  SPECIATION
KW  -  REVEALS
KW  -  ROAD
N2  - Hybridization is a major evolutionary force that can erode genetic differentiation between species, whereas reproductive isolation maintains such differentiation. In studying a hybrid zone between the swallowtail butterflies Papilio syfanius and Papilio maackii (Lepidoptera: Papilionidae), we made the unexpected discovery that genomic substitution rates are unequal between the parental species. This phenomenon creates a novel process in hybridization, where genomic regions most affected by gene flow evolve at similar rates between species, while genomic regions with strong reproductive isolation evolve at species-specific rates. Thus, hybridization mixes evolutionary rates in a way similar to its effect on genetic ancestry. Using coalescent theory, we show that the rate-mixing process provides distinct information about levels of gene flow across different parts of genomes, and the degree of rate-mixing can be predicted quantitatively from relative sequence divergence (FST ) between the hybridizing species at equilibrium. Overall, we demonstrate that reproductive isolation maintains not only genomic differentiation, but also the rate at which differentiation accumulates. Thus, asymmetric rates of evolution provide an additional signature of loci involved in reproductive isolation.
VL  - 11
EP  - 31
AV  - public
ER  -