eprintid: 10165159
rev_number: 10
eprint_status: archive
userid: 699
dir: disk0/10/16/51/59
datestamp: 2023-02-20 12:45:38
lastmod: 2023-07-06 06:10:53
status_changed: 2023-02-20 12:45:38
type: article
metadata_visibility: show
sword_depositor: 699
creators_name: Dusheiko, Geoffrey
creators_name: Agarwal, Kosh
creators_name: Maini, Mala K
title: New Approaches to Chronic Hepatitis B
ispublished: pub
divisions: UCL
divisions: B02
divisions: C10
divisions: D15
divisions: D17
note: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: Chronic hepatitis B is caused by the hepatitis B virus (HBV), a hepatotropic DNA virus that can replicate at high levels and cause minimal disease or severe liver injury. The clinical spectrum of chronic hepatitis B ranges from no symptoms to progressive hepatic fibrosis, advanced cirrhosis, and hepatocellular carcinoma. An estimated 296 million people have chronic hepatitis B, of whom 221 million live in low- and middle-income countries. Without intervention, deaths from HBV are expected to peak at 1.14 million by 2035.
date: 2023-01-05
date_type: published
publisher: MASSACHUSETTS MEDICAL SOC
official_url: http://doi.org/10.1056/NEJMra2211764
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1999658
doi: 10.1056/NEJMra2211764
medium: Print
lyricists_name: Maini, Mala
lyricists_name: Dusheiko, Geoffrey
lyricists_id: KMMAI99
lyricists_id: GDUSH53
actors_name: Maini, Mala
actors_id: KMMAI99
actors_role: owner
full_text_status: public
publication: New England Journal of Medicine
volume: 388
pagerange: 55-69
pages: 15
event_location: United States
citation:        Dusheiko, Geoffrey;    Agarwal, Kosh;    Maini, Mala K;      (2023)    New Approaches to Chronic Hepatitis B.                   New England Journal of Medicine , 388    pp. 55-69.    10.1056/NEJMra2211764 <https://doi.org/10.1056/NEJMra2211764>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10165159/2/Maini_nejmra2211764.pdf