TY  - JOUR
TI  - New Approaches to Chronic Hepatitis B
AV  - public
Y1  - 2023/01/05/
VL  - 388
SP  - 55
EP  - 69
N1  - This version is the version of record. For information on re-use, please refer to the publisher?s terms and conditions.
N2  - Chronic hepatitis B is caused by the hepatitis B virus (HBV), a hepatotropic DNA virus that can replicate at high levels and cause minimal disease or severe liver injury. The clinical spectrum of chronic hepatitis B ranges from no symptoms to progressive hepatic fibrosis, advanced cirrhosis, and hepatocellular carcinoma. An estimated 296 million people have chronic hepatitis B, of whom 221 million live in low- and middle-income countries. Without intervention, deaths from HBV are expected to peak at 1.14 million by 2035.
ID  - discovery10165159
PB  - MASSACHUSETTS MEDICAL SOC
UR  - http://doi.org/10.1056/NEJMra2211764
JF  - New England Journal of Medicine
A1  - Dusheiko, Geoffrey
A1  - Agarwal, Kosh
A1  - Maini, Mala K
ER  -