@article{discovery10165159,
           month = {January},
       publisher = {MASSACHUSETTS MEDICAL SOC},
           title = {New Approaches to Chronic Hepatitis B},
            year = {2023},
         journal = {New England Journal of Medicine},
          volume = {388},
            note = {This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions.},
           pages = {55--69},
          author = {Dusheiko, Geoffrey and Agarwal, Kosh and Maini, Mala K},
        abstract = {Chronic hepatitis B is caused by the hepatitis B virus (HBV), a hepatotropic DNA virus that can replicate at high levels and cause minimal disease or severe liver injury. The clinical spectrum of chronic hepatitis B ranges from no symptoms to progressive hepatic fibrosis, advanced cirrhosis, and hepatocellular carcinoma. An estimated 296 million people have chronic hepatitis B, of whom 221 million live in low- and middle-income countries. Without intervention, deaths from HBV are expected to peak at 1.14 million by 2035.},
             url = {http://doi.org/10.1056/NEJMra2211764}
}