eprintid: 10160415 rev_number: 8 eprint_status: archive userid: 699 dir: disk0/10/16/04/15 datestamp: 2022-11-24 10:29:50 lastmod: 2022-11-24 10:29:50 status_changed: 2022-11-24 10:29:50 type: article metadata_visibility: show sword_depositor: 699 creators_name: Radford, Shellie Jean creators_name: Clarke, Chris creators_name: Shinkins, Bethany creators_name: Leighton, Paul creators_name: Taylor, Stuart creators_name: Moran, Gordon title: Clinical utility of small bowel ultrasound assessment of Crohn's disease in adults: a systematic scoping review ispublished: pub divisions: UCL divisions: B02 divisions: C10 divisions: D17 divisions: FI6 keywords: Crohn's disease, IBD clinical, clinical decision making, inflammatory bowel disease, ultrasonography note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions. abstract: BACKGROUND: Ultrasound (US) is an alternative to magnetic resonance enterography, and has the potential to significantly reduce waiting times, expedite clinical decision-making and improve patient experience. Point of care US is an advantage of the US imaging modality, where same day scanning, interpretation and treatment decisions can be made. AIM: To systematically scope the literature on point of care US use in small bowel Crohn’s disease, generating a comprehensive list of factors relating to the current understanding of clinical utility of this imaging modality. METHODS: Searches included MEDLINE, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, clinicaltrial.gov,‘TRIP’ and Epistemonikos. Reference lists of included studies were hand searched. Search terms were searched for as both keywords and subject headings (MeSH) as appropriate. Searches were performed with the ‘suggested search terms’ and ‘explode’ selection, and restricted to ‘human’, ‘adult’ and ‘English language’ publications. No date limits were applied to be as inclusive as possible. Two investigators conducted abstract and full-text review. No formal quality appraisal process was undertaken; however, quality of sources was considered when reporting findings. A narrative synthesis was conducted. RESULTS: The review included 42 sources from the UK, Europe, Japan, Canada and the USA. Small bowel ultrasound (SBUS) has been shown to be as accurate in detecting the presence of small bowel Crohn’s disease, is quicker, safer and more acceptable to patients, compared with magnetic resonance enterography. SBUS is used widely in central Europe and Canada but has not been embraced in the UK. Further research considering economic evaluation, clinical decision-making and exploration of perceived barriers to future implementation of SBUSs is required. date: 2021-07 date_type: published publisher: BMJ official_url: http://dx.doi.org/10.1136/flgastro-2021-101897 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1963032 doi: 10.1136/flgastro-2021-101897 medium: Electronic-eCollection pii: flgastro-2021-101897 lyricists_name: Taylor, Stuart lyricists_id: STAYL70 actors_name: Taylor, Stuart actors_name: Kalinowski, Damian actors_id: STAYL70 actors_id: DKALI47 actors_role: owner actors_role: impersonator full_text_status: public publication: Frontline Gastroenterology volume: 13 number: 4 pagerange: 280-286 event_location: England citation: Radford, Shellie Jean; Clarke, Chris; Shinkins, Bethany; Leighton, Paul; Taylor, Stuart; Moran, Gordon; (2021) Clinical utility of small bowel ultrasound assessment of Crohn's disease in adults: a systematic scoping review. Frontline Gastroenterology , 13 (4) pp. 280-286. 10.1136/flgastro-2021-101897 <https://doi.org/10.1136/flgastro-2021-101897>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10160415/1/Taylor_Clinical%20utility%20of%20small%20bowel%20ultrasound%20assessment%20of%20Crohns%20disease%20in%20adults_AAM.pdf document_url: https://discovery.ucl.ac.uk/id/eprint/10160415/2/Taylor_Clinical%20utility%20of%20small%20bowel%20ultrasound%20assessment%20of%20Crohns%20disease%20in%20adults_Supplements_AAM.pdf