TY  - JOUR
N1  - © 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
PB  - Elsevier BV
TI  - Microwave-assisted flow synthesis of multicore iron oxide nanoparticles
Y1  - 2022/12//
SN  - 0255-2701
A1  - Panariello, L
A1  - Besenhard, MO
A1  - Damilos, S
A1  - Sergides, A
A1  - Sebastian, V
A1  - Irusta, S
A1  - Tang, J
A1  - Thanh, Nguyen Thi Kim
A1  - Gavriilidis, A
UR  - https://doi.org/10.1016/j.cep.2022.109198
VL  - 182
JF  - Chemical Engineering and Processing - Process Intensification
AV  - public
N2  - Coprecipitation is by far the most common synthesis method for iron oxide nanoparticles (IONPs). However, reproducibility and scalability represent a major challenge. Therefore, innovative processes for scalable production of IONPs are highly sought after. Here, we explored the combination of microwave heating with a flow reactor producing IONPs through coprecipitation. The synthesis was initially studied in a well-characterised microwave-heated flow system, enabling the synthesis of multicore IONPs, with control over both the single core size and the multicore hydrodynamic diameter. The effect of residence time and microwave power was investigated, enabling the synthesis of multicore nanostructures with hydrodynamic diameter between ?35 and 70 nm, with single core size of 3?5 nm. Compared to particles produced under conventional heating, similar single core sizes were observed, though with smaller hydrodynamic diameters. The process comprised of the initial IONP coprecipitation followed by the addition of the stabiliser (citric acid and dextran). The ability of precisely controlling the stabiliser addition time (distinctive of flow reactors), contributed to the synthesis reproducibility. Finally, scale-up by increasing the reactor length and using a different microwave cavity was demonstrated, producing particles of similar structure as those from the small scale system, with a throughput of 3.3 g/h.
KW  - Magnetic nanomaterials
KW  -  Flow chemistry
KW  -  Microwave heating
ID  - discovery10159621
ER  -