eprintid: 10158003 rev_number: 8 eprint_status: archive userid: 699 dir: disk0/10/15/80/03 datestamp: 2023-05-11 15:56:15 lastmod: 2023-05-11 15:56:15 status_changed: 2023-05-11 15:56:15 type: conference_item metadata_visibility: show sword_depositor: 699 creators_name: O'Mara-Eves, Alison creators_name: Kneale, Dylan creators_name: Candy, Bridget creators_name: Sutcliffe, Katy creators_name: Oliver, Sandy creators_name: Cain, Lizzie creators_name: Hutchinson Pascal, Niccola creators_name: Thomas, James title: Recalibration as an approach to context in statistical meta-analyses ispublished: pub divisions: B14 divisions: J81 divisions: B16 divisions: UCL keywords: Statistical meta-analysis, evidence synthesis, systematic review, context, generaliability, secondary data sources abstract: Background: Using evidence from meta-analyses for local decision-making is hampered by the lack of explicit connection between the contexts in which interventions were evaluated and the context in which the evidence is to be applied. New methods are needed to address the question, ‘is there any evidence that the intervention will work differently in an area like mine?’ / Methods: We reanalyzed a meta-analysis of school-based interventions to reduce fat intake. Using observational data, effect sizes were reweighted to reflect the contextual similarity of studies to four UK Local Authorities. Studies that were more like Local Authorities contributed more towards the pooled effect size. / Results: The original meta-analysis found that the intervention was not effective in reducing fat intake. In the recalibration analyses, because contextually relevant studies showed greater effects, the recalibrated pooled effect sizes indicated a larger effect with a narrower confidence interval in three Local Authorities, but the interpretation remained unchanged in a fourth. The findings held under both fixed effect and random effects specifications. / Discussion: For three of the local authorities examined, we have greater confidence that school-based interventions will have an impact on reducing fat intake. Recalibration may give a contextually-nuanced estimate for a given local context. date: 2022-10-18 date_type: published official_url: https://wwgs2022.mailchimpsites.com/ oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1984257 lyricists_name: O'Mara-Eves, Alison lyricists_id: AJOMA15 actors_name: O'Mara-Eves, Alison actors_id: AJOMA15 actors_role: owner full_text_status: public pres_type: presentation event_title: 2022 What Works Global Summit (WWGS) event_location: Virtual conference event_dates: 18 - 20 October 2022 citation: O'Mara-Eves, Alison; Kneale, Dylan; Candy, Bridget; Sutcliffe, Katy; Oliver, Sandy; Cain, Lizzie; Hutchinson Pascal, Niccola; O'Mara-Eves, Alison; Kneale, Dylan; Candy, Bridget; Sutcliffe, Katy; Oliver, Sandy; Cain, Lizzie; Hutchinson Pascal, Niccola; Thomas, James; - view fewer <#> (2022) Recalibration as an approach to context in statistical meta-analyses. Presented at: 2022 What Works Global Summit (WWGS), Virtual conference. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10158003/1/221018%20WWGS%20Recalibration%20as%20an%20Approach%20to%20Context%20in%20Statistical%20Meta-analyses_final.pdf