%C Virtual conference %T How co-production underpinned the development of a logic model and testing of novel statistical methods for evidence synthesis %X Background: The CEPHI project sought to develop and test four methods for synthesizing evidence that better accounted for context than standard statistical meta-analysis approaches. To explore context, we had to understand what was important in different contexts. We identified co-production as an approach to achieve this. / Methods: Supported by the Co-Production Collective, we worked closely with an Advisory Group of people with lived, professional, and/or academic expertise. We held a series of workshops with others bringing lived, professional, and/or academic expertise, to co-produce a logic model that subsequently informed novel synthesis methods. Evaluation of the co-production element was through reflexive notes, feedback from participants, and discussions during and after the project. / Results: The impact of co-production was profound. It fundamentally redesigned the entire logic model. This enabled novel statistical methods to answer important questions about context and impact. There were emotional impacts (highs and lows) and resource implications. / Discussion: Co-production is a powerful way to develop logic models and to inform synthesis methods development, by focusing on what is important to the affected communities. We will discuss lessons learned, what we would do differently next time, and what might be some of the key conditions and mechanisms for meaningful co-production. %A Alison O'Mara-Eves %A Dylan Kneale %A Sandy Oliver %A Lizzie Cain %A Niccola Hutchinson Pascal %A Jessica Catchpole %A Angela Chesworth %A Bridget Candy %A Katy Sutcliffe %A James Thomas %D 2022 %K co-production, logic model, evidence synthesis, systematic review, meta-analysis %L discovery10158002