TY  - JOUR
PB  - BMJ PUBLISHING GROUP
VL  - 12
IS  - 5
JF  - BMJ Open
TI  - Youth Culturally adapted Manual Assisted Problem Solving Training (YCMAP) in Pakistani adolescent with a history of self-harm: protocol for multicentre clinical and cost-effectiveness randomised controlled trial
EP  - 8
UR  - http://dx.doi.org/10.1136/bmjopen-2021-056301
N1  - © Author(s) (or their employer[s]) 2022. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/).
Y1  - 2022/05//
A1  - Husain, Nusrat
A1  - Tofique, Sehrish
A1  - Chaudhry, Imran B
A1  - Kiran, Tayyeba
A1  - Taylor, Peter
A1  - Williams, Christopher
A1  - Memon, Rakhshi
A1  - Aggarwal, Shilpa
A1  - Alvi, Mohsin Hassan
A1  - Ananiadou, S
A1  - Ansari, Moin Ahmad
A1  - Aseem, Saadia
A1  - Beck, Andrew
A1  - Alam, Sumira
A1  - Colucci, Erminia
A1  - Davidson, Kate
A1  - Edwards, Sarah
A1  - Emsley, Richard
A1  - Green, Jonathan
A1  - Gumber, Anil
A1  - Hawton, Keith
A1  - Jafri, Farhat
A1  - Khaliq, Ayesha
A1  - Mason, Thomas
A1  - Mcreath, Ann
A1  - Minhas, Ayesha
A1  - Naeem, Farooq
A1  - Naqvi, Haider Ali
A1  - Noureen, Amna
A1  - Panagioti, Maria
A1  - Patel, Anita
A1  - Poppleton, Aaron
A1  - Shiri, Tinevimbo
A1  - Simic, Mima
A1  - Sultan, Sarwat
A1  - Nizami, Asad Tamizuddin
A1  - Zadeh, Zainab
A1  - Zafar, Shehla Naeem
A1  - Chaudhry, Nasim
AV  - public
ID  - discovery10154454
N2  - INTRODUCTION: Suicide is a global health concern. Sociocultural factors have an impact on self-harm and suicide rates. In Pakistan, both self-harm and suicide are considered as criminal offence's and are condemned on both religious and social grounds. The proposed intervention 'Youth Culturally Adapted Manual Assisted Problem Solving Training (YCMAP)' is based on principles of problem-solving and cognitive-behavioural therapy. YCMAP is a brief, culturally relevant, scalable intervention that can be implemented in routine clinical practice if found to be effective. METHOD AND ANALYSIS: A multicentre rater blind randomised controlled trial to evaluate the clinical and cost-effectiveness of YCMAP including a sample of 652 participants, aged 12-18 years, presenting to general physicians/clinicians, emergency room after self harm or self referrals. We will test the effectiveness of 8-10 individual sessions of YCMAP delivered over 3?months compared with treatment as usual. Primary outcome measure is repetition of self-harm at 12 months. The seconday outcomes include reduction in suicidal ideation, hopelessness and distress and improvement in health related quality of life. Assessments will be completed at baseline, 3, 6, 9 and 12?months postrandomisation. The nested qualitative component will explore perceptions about management of self-harm and suicide prevention among adolescents and investigate participants' experiences with YCMAP. The study will be guided by the theory of change approach to ensure that the whole trial is centred around needs of the end beneficiaries as key stakeholders in the process. ETHICS AND DISSEMINATION: Ethics approval has been obtained from the Ethics Committee of University of Manchester, the National Bioethics Committee in Pakistan. The findings of this study will be disseminated through community workshops, social media, conference presentations and peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT04131179.
ER  -