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<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/dc/terms/title> "Phase 1, dose-escalation study of guadecitabine (SGI-110) in combination with pembrolizumab in patients with solid tumors"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/ontology/bibo/abstract> "Background: Data suggest that immunomodulation induced by DNA hypomethylating agents can sensitize tumors to immune checkpoint inhibitors. We conducted a phase 1 dose-escalation trial (NCT02998567) of guadecitabine and pembrolizumab in patients with advanced solid tumors. We hypothesized that guadecitabine will overcome pembrolizumab resistance. Methods: Patients received guadecitabine (45 mg/m 2 or 30 mg/m 2, administered subcutaneously on days 1-4), with pembrolizumab (200 mg administered intravenously starting from cycle 2 onwards) every 3 weeks. Primary endpoints were safety, tolerability and maximum tolerated dose; secondary and exploratory endpoints included objective response rate (ORR), changes in methylome, transcriptome, immune contextures in pre-treatment and on-treatment tumor biopsies. Results: Between January 2017 and January 2020, 34 patients were enrolled. The recommended phase II dose was guadecitabine 30 mg/m 2, days 1-4, and pembrolizumab 200 mg on day 1 every 3 weeks. Two dose-limiting toxicities (neutropenia, febrile neutropenia) were reported at guadecitabine 45 mg/m 2 with none reported at guadecitabine 30 mg/m 2. The most common treatment-related adverse events (TRAEs) were neutropenia (58.8%), fatigue (17.6%), febrile neutropenia (11.8%) and nausea (11.8%). Common, grade 3+ TRAEs were neutropaenia (38.2%) and febrile neutropaenia (11.8%). There were no treatment-related deaths. Overall, 30 patients were evaluable for antitumor activity; ORR was 7% with 37% achieving disease control (progression-free survival) for ≥24 weeks. Of 12 evaluable patients with non-small cell lung cancer, 10 had been previously treated with immune checkpoint inhibitors with 5 (42%) having disease control ≥24 weeks (clinical benefit). Reduction in LINE-1 DNA methylation following treatment in blood (peripheral blood mononuclear cells) and tissue samples was demonstrated and methylation at transcriptional start site and 5' untranslated region gene regions showed enriched negative correlation with gene expression. Increases in intra-tumoural effector T-cells were seen in some responding patients. Patients having clinical benefit had high baseline inflammatory signature on RNAseq analyses. Conclusions: Guadecitabine in combination with pembrolizumab is tolerable with biological and anticancer activity. Reversal of previous resistance to immune checkpoint inhibitors is demonstrated."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/dc/terms/date> "2022-06-18" .
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<https://discovery.ucl.ac.uk/id/eprint/10152373#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_28> <https://discovery.ucl.ac.uk/id/person/ext-422eea5894f6ff343de00d364f1fe6df> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-abe871b5f9673e9598ed442b180a17fe> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10152373#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10152373#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_29> <https://discovery.ucl.ac.uk/id/person/ext-abe871b5f9673e9598ed442b180a17fe> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4e6ce74a40a1274ab791e5be8dc813ce> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10152373#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10152373#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_30> <https://discovery.ucl.ac.uk/id/person/ext-4e6ce74a40a1274ab791e5be8dc813ce> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-378a13574e2766dfa14c17f137a730d3> .
<https://discovery.ucl.ac.uk/id/eprint/10152373> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10152373#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10152373#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_31> <https://discovery.ucl.ac.uk/id/person/ext-378a13574e2766dfa14c17f137a730d3> .
<https://discovery.ucl.ac.uk/id/person/ext-422eea5894f6ff343de00d364f1fe6df> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-422eea5894f6ff343de00d364f1fe6df> <http://xmlns.com/foaf/0.1/givenName> "U"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-422eea5894f6ff343de00d364f1fe6df> <http://xmlns.com/foaf/0.1/familyName> "Banerji"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-422eea5894f6ff343de00d364f1fe6df> <http://xmlns.com/foaf/0.1/name> "U Banerji"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3d38fd4b3ee89ad5ebe051c24e39364a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-3d38fd4b3ee89ad5ebe051c24e39364a> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3d38fd4b3ee89ad5ebe051c24e39364a> <http://xmlns.com/foaf/0.1/familyName> "Pal"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3d38fd4b3ee89ad5ebe051c24e39364a> <http://xmlns.com/foaf/0.1/name> "A Pal"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-98ae760866e1f341c8c9cea223fbc050> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-98ae760866e1f341c8c9cea223fbc050> <http://xmlns.com/foaf/0.1/givenName> "W"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-98ae760866e1f341c8c9cea223fbc050> <http://xmlns.com/foaf/0.1/familyName> "Chen"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-98ae760866e1f341c8c9cea223fbc050> <http://xmlns.com/foaf/0.1/name> "W Chen"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1a2b62b3c17d1735effbd567071c48db> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-1a2b62b3c17d1735effbd567071c48db> <http://xmlns.com/foaf/0.1/givenName> "I"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1a2b62b3c17d1735effbd567071c48db> <http://xmlns.com/foaf/0.1/familyName> "Figueiredo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1a2b62b3c17d1735effbd567071c48db> <http://xmlns.com/foaf/0.1/name> "I Figueiredo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2fd2b2c8dd79746ed6d78c14548b0753> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-2fd2b2c8dd79746ed6d78c14548b0753> <http://xmlns.com/foaf/0.1/givenName> "T"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2fd2b2c8dd79746ed6d78c14548b0753> <http://xmlns.com/foaf/0.1/familyName> "Prout"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-2fd2b2c8dd79746ed6d78c14548b0753> <http://xmlns.com/foaf/0.1/name> "T Prout"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-96828067a079dfa433d486127ed1ad92> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-96828067a079dfa433d486127ed1ad92> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-96828067a079dfa433d486127ed1ad92> <http://xmlns.com/foaf/0.1/familyName> "Chénard-Poirier"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-96828067a079dfa433d486127ed1ad92> <http://xmlns.com/foaf/0.1/name> "M Chénard-Poirier"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-62a1d8af50ec8a3bb9bef1a1ea944d1f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-62a1d8af50ec8a3bb9bef1a1ea944d1f> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-62a1d8af50ec8a3bb9bef1a1ea944d1f> <http://xmlns.com/foaf/0.1/familyName> "Riisnaes"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-62a1d8af50ec8a3bb9bef1a1ea944d1f> <http://xmlns.com/foaf/0.1/name> "R Riisnaes"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e6ce74a40a1274ab791e5be8dc813ce> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-4e6ce74a40a1274ab791e5be8dc813ce> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e6ce74a40a1274ab791e5be8dc813ce> <http://xmlns.com/foaf/0.1/familyName> "De Bono"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e6ce74a40a1274ab791e5be8dc813ce> <http://xmlns.com/foaf/0.1/name> "J De Bono"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4081a2c44cfc340acd3b386ae6777e37> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-4081a2c44cfc340acd3b386ae6777e37> <http://xmlns.com/foaf/0.1/givenName> "B"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4081a2c44cfc340acd3b386ae6777e37> <http://xmlns.com/foaf/0.1/familyName> "Jenkins"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4081a2c44cfc340acd3b386ae6777e37> <http://xmlns.com/foaf/0.1/name> "B Jenkins"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d4411b2c024870be3c7b784f87d249fe> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-d4411b2c024870be3c7b784f87d249fe> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d4411b2c024870be3c7b784f87d249fe> <http://xmlns.com/foaf/0.1/familyName> "Parmar"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d4411b2c024870be3c7b784f87d249fe> <http://xmlns.com/foaf/0.1/name> "M Parmar"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-5c9ec90820897904607e22475ded79ac> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-5c9ec90820897904607e22475ded79ac> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-5c9ec90820897904607e22475ded79ac> <http://xmlns.com/foaf/0.1/familyName> "Ameratunga"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-5c9ec90820897904607e22475ded79ac> <http://xmlns.com/foaf/0.1/name> "M Ameratunga"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfba77236153dda8ce6383d23207990> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfba77236153dda8ce6383d23207990> <http://xmlns.com/foaf/0.1/givenName> "W"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfba77236153dda8ce6383d23207990> <http://xmlns.com/foaf/0.1/familyName> "Yuan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfba77236153dda8ce6383d23207990> <http://xmlns.com/foaf/0.1/name> "W Yuan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-873da34ad372cc2c75fdeb1a03cfa7cd> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-873da34ad372cc2c75fdeb1a03cfa7cd> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-873da34ad372cc2c75fdeb1a03cfa7cd> <http://xmlns.com/foaf/0.1/familyName> "Bertan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-873da34ad372cc2c75fdeb1a03cfa7cd> <http://xmlns.com/foaf/0.1/name> "C Bertan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-abe871b5f9673e9598ed442b180a17fe> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-abe871b5f9673e9598ed442b180a17fe> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-abe871b5f9673e9598ed442b180a17fe> <http://xmlns.com/foaf/0.1/familyName> "Lopez"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-abe871b5f9673e9598ed442b180a17fe> <http://xmlns.com/foaf/0.1/name> "J Lopez"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8a72d9b54aa34caf3344fa6eacda3cf7> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-8a72d9b54aa34caf3344fa6eacda3cf7> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8a72d9b54aa34caf3344fa6eacda3cf7> <http://xmlns.com/foaf/0.1/familyName> "Carreira"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8a72d9b54aa34caf3344fa6eacda3cf7> <http://xmlns.com/foaf/0.1/name> "S Carreira"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-cd33ac5cb8dbb895325671d9d5c879e2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-cd33ac5cb8dbb895325671d9d5c879e2> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-cd33ac5cb8dbb895325671d9d5c879e2> <http://xmlns.com/foaf/0.1/familyName> "Curcean"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-cd33ac5cb8dbb895325671d9d5c879e2> <http://xmlns.com/foaf/0.1/name> "A Curcean"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d1913c24b0547d9953ff7ea923aa5081> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-d1913c24b0547d9953ff7ea923aa5081> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d1913c24b0547d9953ff7ea923aa5081> <http://xmlns.com/foaf/0.1/familyName> "Crespo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d1913c24b0547d9953ff7ea923aa5081> <http://xmlns.com/foaf/0.1/name> "M Crespo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16da47a2ad9689e5e3c7b4130c88f0b0> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-16da47a2ad9689e5e3c7b4130c88f0b0> <http://xmlns.com/foaf/0.1/givenName> "B"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16da47a2ad9689e5e3c7b4130c88f0b0> <http://xmlns.com/foaf/0.1/familyName> "Gurel"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16da47a2ad9689e5e3c7b4130c88f0b0> <http://xmlns.com/foaf/0.1/name> "B Gurel"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-07808f4967dca119ec1f0482f641d284> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-07808f4967dca119ec1f0482f641d284> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-07808f4967dca119ec1f0482f641d284> <http://xmlns.com/foaf/0.1/familyName> "Pereira"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-07808f4967dca119ec1f0482f641d284> <http://xmlns.com/foaf/0.1/name> "R Pereira"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-90c8993fbc897aafeadd2e6cb845ded3> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-90c8993fbc897aafeadd2e6cb845ded3> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-90c8993fbc897aafeadd2e6cb845ded3> <http://xmlns.com/foaf/0.1/familyName> "Baker"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-90c8993fbc897aafeadd2e6cb845ded3> <http://xmlns.com/foaf/0.1/name> "C Baker"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d51984bb686a922a9ccd59937c5f8b65> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-d51984bb686a922a9ccd59937c5f8b65> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d51984bb686a922a9ccd59937c5f8b65> <http://xmlns.com/foaf/0.1/familyName> "Turner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d51984bb686a922a9ccd59937c5f8b65> <http://xmlns.com/foaf/0.1/name> "A Turner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-953353cb1a02196f2178023c6f614fbc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-953353cb1a02196f2178023c6f614fbc> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-953353cb1a02196f2178023c6f614fbc> <http://xmlns.com/foaf/0.1/familyName> "Morilla"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-953353cb1a02196f2178023c6f614fbc> <http://xmlns.com/foaf/0.1/name> "R Morilla"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-21be7b67b4d3ed4c93417e3e66535b8a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-21be7b67b4d3ed4c93417e3e66535b8a> <http://xmlns.com/foaf/0.1/givenName> "D"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-21be7b67b4d3ed4c93417e3e66535b8a> <http://xmlns.com/foaf/0.1/familyName> "Papadatos-Pastos"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/person/ext-9ed1e88bc9e80e82f246cee2c0f601a6> <http://xmlns.com/foaf/0.1/familyName> "Masrour"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9ed1e88bc9e80e82f246cee2c0f601a6> <http://xmlns.com/foaf/0.1/name> "N Masrour"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3d4c762a925eebc39f6bc0a5465dee2d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-3d4c762a925eebc39f6bc0a5465dee2d> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3d4c762a925eebc39f6bc0a5465dee2d> <http://xmlns.com/foaf/0.1/familyName> "Yap"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3d4c762a925eebc39f6bc0a5465dee2d> <http://xmlns.com/foaf/0.1/name> "C Yap"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0ec808059b541075fd0bc648d1b1b700> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-0ec808059b541075fd0bc648d1b1b700> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0ec808059b541075fd0bc648d1b1b700> <http://xmlns.com/foaf/0.1/familyName> "Brown"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0ec808059b541075fd0bc648d1b1b700> <http://xmlns.com/foaf/0.1/name> "R Brown"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/person/ext-a68de30add2a32c6671ebd997cee8894> <http://xmlns.com/foaf/0.1/familyName> "Zachariou"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a68de30add2a32c6671ebd997cee8894> <http://xmlns.com/foaf/0.1/name> "A Zachariou"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/person/ext-cd16fa11d235e7c04c87f230407bb9a0> <http://xmlns.com/foaf/0.1/familyName> "Ferreira"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-cd16fa11d235e7c04c87f230407bb9a0> <http://xmlns.com/foaf/0.1/name> "A Ferreira"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/person/ext-378a13574e2766dfa14c17f137a730d3> <http://xmlns.com/foaf/0.1/familyName> "Minchom"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-378a13574e2766dfa14c17f137a730d3> <http://xmlns.com/foaf/0.1/name> "A Minchom"^^<http://www.w3.org/2001/XMLSchema#string> .
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<https://discovery.ucl.ac.uk/id/person/ext-18dda69308ff5942f04dfd3ae1cc615d> <http://xmlns.com/foaf/0.1/familyName> "Miranda"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-18dda69308ff5942f04dfd3ae1cc615d> <http://xmlns.com/foaf/0.1/name> "S Miranda"^^<http://www.w3.org/2001/XMLSchema#string> .
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