@article{discovery10147804,
       publisher = {Royal Society of Chemistry (RSC)},
           month = {April},
            year = {2022},
           title = {Mechanoenzymatic reactions with whole cell transaminases: shaken, not stirred},
         journal = {Green Chemistry},
            note = {This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/).},
        abstract = {Mechanochemical reactions have emerged in recent years as a green synthetic method because reactions can be performed more rapidly and using less solvent than traditional synthetic approaches. To date, very few mechanoenzymatic reactions have been described. For the first time, transaminases, which are widely used for the amination of aldehydes and ketones, have been used here under mechanoenzymatic conditions to produce amines using significantly less aqueous medium than conventional biocatalytic reactions. The direct use of whole cells was also possible and shorter reaction times could be used to provide amines efficiently with high yields and stereoselectivities.},
             url = {https://doi.org/10.1039/d2gc01006b},
          author = {Hailes, Helen and Carter, Eve and Ambrose-Dempster, Esther and Ward, John M and Sheppard, Tom}
}