eprintid: 10145205 rev_number: 7 eprint_status: archive userid: 699 dir: disk0/10/14/52/05 datestamp: 2022-03-16 16:15:58 lastmod: 2022-03-16 16:15:58 status_changed: 2022-03-16 16:15:58 type: article metadata_visibility: show sword_depositor: 699 creators_name: Lopez-Gonzalez, Desiree creators_name: Wells, Jonathan CK creators_name: Parra-Carriedo, Alicia creators_name: Bilbao, Gladys creators_name: Mendez, Martín creators_name: Clark, Patricia title: Body Composition Assessment in Mexican Children and Adolescents. Part 1: Comparisons between Skinfold-Thickness, Dual X-ray Absorptiometry, Air-Displacement Plethysmography, Deuterium Oxide Dilution, and Magnetic Resonance Imaging with the 4-C Model ispublished: pub divisions: UCL divisions: G25 divisions: D13 divisions: B02 keywords: MRI 6, air-displacement plethysmography (ADP), body composition, children and adolescents, deuterium dilution, dual X-ray absorptiometry (DXA), skinfold-thickness note: © 2022 MDPI. This is an open access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). abstract: The evaluation of body composition (BC) is relevant in the evaluation of children's health-disease states. Different methods and devices are used to estimate BC. The availability of methods and the clinical condition of the patient usually defines the ideal approach to be used. In this cross-sectional study, we evaluate the accuracy of different methods to estimate BC in Mexican children and adolescents, using the 4-C model as the reference. In a sample of 288 Mexican children and adolescents, 4-C body composition assessment, skinfold-thickness (SF), dual-energy X-ray absorptiometry (DXA), air displacement plethysmography (ADP), and deuterium dilution (D2O) were performed, along with MRI in a subsample (52 participants). The analysis of validity was performed by correlation analysis, linear regression, and the Bland-Altman method. All methods analyzed showed strong correlations for FM with 4-C values and between each other; however, DXA and MRI overestimated FM, whereas skinfolds and ADP under-estimated FM. Conclusion: The clinical assessment of BC by means of SF, ADP, DXA, MRI and D2O correlated well with the 4-C model and between them, providing evidence of their clinical validity and utility. The results from different methods are not interchangeable. Preference between methods may depend on their availability and the specific clinical setting. date: 2022-03 date_type: published publisher: MDPI AG official_url: https://doi.org/10.3390/nu14051073 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1944517 doi: 10.3390/nu14051073 medium: Electronic pii: nu14051073 lyricists_name: Wells, Jonathan lyricists_id: JWELL04 actors_name: Barczynska, Patrycja actors_id: PBARC91 actors_role: owner funding_acknowledgements: 2015-2 261682 [Consejo Nacional de Ciencia y Tecnología]; 055 [seca gmbh & co. kg Hammer Steindamm 3-25 22089 Hamburg | Germany] full_text_status: public publication: Nutrients volume: 14 number: 5 article_number: 1073 event_location: Switzerland citation: Lopez-Gonzalez, Desiree; Wells, Jonathan CK; Parra-Carriedo, Alicia; Bilbao, Gladys; Mendez, Martín; Clark, Patricia; (2022) Body Composition Assessment in Mexican Children and Adolescents. Part 1: Comparisons between Skinfold-Thickness, Dual X-ray Absorptiometry, Air-Displacement Plethysmography, Deuterium Oxide Dilution, and Magnetic Resonance Imaging with the 4-C Model. Nutrients , 14 (5) , Article 1073. 10.3390/nu14051073 <https://doi.org/10.3390/nu14051073>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10145205/1/Wells_nutrients-14-01073.pdf