TY - JOUR N2 - The evaluation of body composition (BC) is relevant in the evaluation of children's health-disease states. Different methods and devices are used to estimate BC. The availability of methods and the clinical condition of the patient usually defines the ideal approach to be used. In this cross-sectional study, we evaluate the accuracy of different methods to estimate BC in Mexican children and adolescents, using the 4-C model as the reference. In a sample of 288 Mexican children and adolescents, 4-C body composition assessment, skinfold-thickness (SF), dual-energy X-ray absorptiometry (DXA), air displacement plethysmography (ADP), and deuterium dilution (D2O) were performed, along with MRI in a subsample (52 participants). The analysis of validity was performed by correlation analysis, linear regression, and the Bland-Altman method. All methods analyzed showed strong correlations for FM with 4-C values and between each other; however, DXA and MRI overestimated FM, whereas skinfolds and ADP under-estimated FM. Conclusion: The clinical assessment of BC by means of SF, ADP, DXA, MRI and D2O correlated well with the 4-C model and between them, providing evidence of their clinical validity and utility. The results from different methods are not interchangeable. Preference between methods may depend on their availability and the specific clinical setting. ID - discovery10145205 PB - MDPI AG UR - https://doi.org/10.3390/nu14051073 JF - Nutrients A1 - Lopez-Gonzalez, Desiree A1 - Wells, Jonathan CK A1 - Parra-Carriedo, Alicia A1 - Bilbao, Gladys A1 - Mendez, Martín A1 - Clark, Patricia KW - MRI 6 KW - air-displacement plethysmography (ADP) KW - body composition KW - children and adolescents KW - deuterium dilution KW - dual X-ray absorptiometry (DXA) KW - skinfold-thickness TI - Body Composition Assessment in Mexican Children and Adolescents. Part 1: Comparisons between Skinfold-Thickness, Dual X-ray Absorptiometry, Air-Displacement Plethysmography, Deuterium Oxide Dilution, and Magnetic Resonance Imaging with the 4-C Model AV - public VL - 14 Y1 - 2022/03// IS - 5 N1 - © 2022 MDPI. This is an open access article distributed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). ER -