%0 Journal Article %A Hitchcock, C %A Rudokaite, J %A Haag, C %A Patel, SD %A Smith, AJ %A Kuhn, I %A Jermann, F %A Ma, SH %A Kuyken, W %A Williams, JMG %A Watkins, E %A Bockting, CLH %A Crane, C %A Fisher, D %A Dalgleish, T %D 2022 %F discovery:10143484 %I Elsevier BV %J Behaviour Research and Therapy %K Autobiographical memory, Cogntive therapy, Individual patient data meta-analysis, Mindfulness, Treatment response %T Autobiographical memory style and clinical outcomes following mindfulness-based cognitive therapy (MBCT): An individual patient data meta-analysis %U https://discovery.ucl.ac.uk/id/eprint/10143484/ %V 151 %X The ability to retrieve specific, single-incident autobiographical memories has been consistently posited as a predictor of recurrent depression. Elucidating the role of autobiographical memory specificity in patient-response to depressive treatments may improve treatment efficacy and facilitate use of science-driven interventions. We used recent methodological advances in individual patient data meta-analysis to determine a) whether memory specificity is improved following mindfulness-based cognitive therapy (MBCT), relative to control interventions, and b) whether pre-treatment memory specificity moderates treatment response. All bar one study evaluated MBCT for relapse prevention for depression. Our initial analysis therefore focussed on MBCT datasets only(n = 708), then were repeated including the additional dataset(n = 880). Memory specificity did not significantly differ from baseline to post-treatment for either MBCT and Control interventions. There was no evidence that baseline memory specificity predicted treatment response in terms of symptom-levels, or risk of relapse. Findings raise important questions regarding the role of memory specificity in depressive treatments. %Z Copyright © 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).