?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Array-Based+Beamforming+to+the+Vertebral+Canal%3A+Demonstration+of+Feasibility&rft.creator=Xu%2C+Rui&rft.creator=O'Reilly%2C+Meaghan+Anne&rft.description=Focused+ultrasound+blood-spinal+cord+barrier+opening+is+a+promising+new+method+for+improving+the+non-invasive+delivery+of+therapeutic+agents+to+the+spinal+cord.+A+custom+64-element+phased+array+was+built%2C+based+on+the+design+of+a+component+of+a+spine-specific+array+for+focusing+ultrasound+through+vertebral+laminae+and+correcting+vertebra-induced+distortions.+Geometric+and+hydrophone+delays+were+tested+in+each+thoracic+vertebra+in+an+ex+vivo+spine+(n%3D12).+Pressure+fields+were+measured+in+each+canal+to+measure+focal+aberrations.+Geometric+delays+produced+foci+shifted+by+2.4%C2%B11.7+mm+from+the+target%2C+while+hydrophone+delays+produced+foci+1.3%C2%B11.1+mm+from+the+target.+Simulation+showed+good+correlation+with+hydrophone+delays+and+may+be+a+viable+non-invasive+method+for+phase+corrections.+This+work+demonstrates+the+feasibility+of+transvertebral+ultrasound+beamforming+with+a+phased-array.&rft.publisher=IEEE&rft.date=2021-11-15&rft.type=Proceedings+paper&rft.language=eng&rft.source=+++++In%3A++IEEE+International+Ultrasonics+Symposium%2C+IUS.++++IEEE+(2021)++++(In+press).++&rft.format=text&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F10143014%2F1%2FIEEE_IUS_Array_Based_Beamforming%2520copy.pdf&rft.identifier=https%3A%2F%2Fdiscovery.ucl.ac.uk%2Fid%2Feprint%2F10143014%2F&rft.rights=open