%P L41-L44 %D 2006 %X We present new observations of the Cep A East region of massive star formation and describe an extended and dynamically distinct feature not previously recognized. This feature is present in emission from H2CS, OCS, CH3OH, and HDO at −5.5 km s−1 but is not traced by the conventional tracers of star-forming regions, H2S, SO2, SO, and CS. The feature is extended up to at least 0.1 pc. We show that the feature is neither a hot core nor a shocked outflow. However, the chemistry of the feature is consistent with predictions from a model of an eroding interface between a fast wind and a dense core; mixing between the two media occurs in the interface on a timescale of 10–50 yr. If these observations are confirmed by detailed maps and by detections in species also predicted to be abundant (e.g., HCO+, H2CO, and NH3), this feature would be the first detection of such an interface in regions of massive star formation. An important implication of the model is that a significant reservoir of sulfur in grain mantles is required to be in the form of OCS. %A C. Codella %A S. Viti %A D.A. Williams %A R. Bachiller %J The Astrophysical Journal %N 1 %V 644 %L discovery10142 %T First evidence for molecular interfaces between outflows and ambient clouds in high-mass star-forming regions?