eprintid: 10133535
rev_number: 26
eprint_status: archive
userid: 608
dir: disk0/10/13/35/35
datestamp: 2021-08-27 09:48:48
lastmod: 2022-05-06 09:57:17
status_changed: 2021-08-27 09:48:48
type: article
metadata_visibility: show
creators_name: Saville, NM
creators_name: Cortina-Borja, M
creators_name: De Stavola, BL
creators_name: Pomeroy, E
creators_name: Marphatia, A
creators_name: Reid, A
creators_name: Manandhar, DS
creators_name: Wells, JCK
title: Comprehensive analysis of the association of seasonal variability with maternal and neonatal nutrition in lowland Nepal
ispublished: inpress
divisions: UCL
divisions: B02
divisions: D01
divisions: D13
divisions: G25
keywords: seasonality, cosinor models, Nepal, newborn anthropometry,
nutrition in pregnancy
note: Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of The Nutrition Society. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
abstract: Objective:
to provide a comprehensive seasonal analysis of pregnant mothers’ eating behaviour and maternal/newborn nutritional status in an undernourished population from lowland rural Nepal, where weather patterns, agricultural labour, food availability and disease prevalence vary seasonally. /

Design:
Secondary analysis of cluster-randomized Low Birth Weight South Asia Trial data, applying cosinor analysis to predict seasonal patterns. /

Outcomes: maternal mid-upper arm circumference (MUAC), body mass index (BMI), dietary diversity, meals per day, eating down and food aversion in pregnancy (≥31 weeks’ gestation), and neonatal z-scores of length- (LAZ), weight- (WAZ) and head circumference-for-age (HCAZ) and weight-for-length (WLZ). /

Setting:
rural areas of Dhanusha and Mahottari districts in plains Nepal. /

Participants:
2831 mothers aged 13 to 50 and 3330 neonates. /

Results:
We found seasonal patterns in newborn anthropometry and pregnant mothers’ anthropometry, meal frequency, dietary diversity, food aversion, and eating down. Seasonality in intake varied by food group. Offspring anthropometry broadly tracked mothers’. Annual amplitudes in mothers’ MUAC and BMI were 0.27kg/m2 and 0.22cm, with peaks post-harvest and nadirs in October when food insecurity peaked. Annual LAZ, WAZ and WLZ amplitudes were 0.125, 0.159 and 0.411 z-scores. Neonates were shortest but least thin (higher WLZ) in winter (December/January). In the hot season, WLZ was lowest (May/June) while LAZ was highest (March and August). HCAZ did not vary significantly. Food aversion and eating down peaked pre-monsoon (April/May). /

Conclusions:
Our analyses revealed complex seasonal patterns in maternal nutrition and neonatal size. Seasonality should be accounted for when designing and evaluating public heath nutrition interventions.
date: 2021-08-23
date_type: published
publisher: Cambridge University Press (CUP)
official_url: https://doi.org/10.1017/s1368980021003633
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1883615
doi: 10.1017/s1368980021003633
lyricists_name: Cortina Borja, Mario
lyricists_name: De Stavola, Bianca
lyricists_name: Saville, Naomi
lyricists_name: Wells, Jonathan
lyricists_id: MCORT36
lyricists_id: BLDES34
lyricists_id: NMSAV73
lyricists_id: JWELL04
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
full_text_status: public
publication: Public Health Nutrition
issn: 1475-2727
citation:        Saville, NM;    Cortina-Borja, M;    De Stavola, BL;    Pomeroy, E;    Marphatia, A;    Reid, A;    Manandhar, DS;           Saville, NM;  Cortina-Borja, M;  De Stavola, BL;  Pomeroy, E;  Marphatia, A;  Reid, A;  Manandhar, DS;  Wells, JCK;   - view fewer <#>    (2021)    Comprehensive analysis of the association of seasonal variability with maternal and neonatal nutrition in lowland Nepal.                   Public Health Nutrition        10.1017/s1368980021003633 <https://doi.org/10.1017/s1368980021003633>.    (In press).    Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10133535/7/Saville_div-class-title-comprehensive-analysis-of-the-association-of-seasonal-variability-with-maternal-and-neonatal-nutrition-in-lowland-nepal-div.pdf