<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10133175> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/title> "Genetic Polymorphisms Related to VO2max Adaptation Are Associated With Elite Rugby Union Status and Competitive Marathon Performance"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/abstract> "PURPOSE: Genetic polymorphisms have been associated with the adaptation to training in maximal oxygen uptake (V˙O2max). However, the genotype distribution of selected polymorphisms in athletic cohorts is unknown, with their influence on performance characteristics also undetermined. This study investigated whether the genotype distributions of 3 polymorphisms previously associated with V˙O2max training adaptation are associated with elite athlete status and performance characteristics in runners and rugby athletes, competitors for whom aerobic metabolism is important. METHODS: Genomic DNA was collected from 732 men including 165 long-distance runners, 212 elite rugby union athletes, and 355 nonathletes. Genotype and allele frequencies of PRDM1 rs10499043 C/T, GRIN3A rs1535628 G/A, and KCNH8 rs4973706 T/C were compared between athletes and nonathletes. Personal-best marathon times in runners, as well as in-game performance variables and playing position, of rugby athletes were analyzed according to genotype. RESULTS: Runners with PRDM1 T alleles recorded marathon times ∼3 minutes faster than CC homozygotes (02:27:55 [00:07:32] h vs 02:31:03 [00:08:24] h, P = .023). Rugby athletes had 1.57 times greater odds of possessing the KCNH8 TT genotype than nonathletes (65.5% vs 54.7%, χ2 = 6.494, P = .013). No other associations were identified. CONCLUSIONS: This study is the first to demonstrate that polymorphisms previously associated with V˙O2max training adaptations in nonathletes are also associated with marathon performance (PRDM1) and elite rugby union status (KCNH8). The genotypes and alleles previously associated with superior endurance-training adaptation appear to be advantageous in long-distance running and achieving elite status in rugby union."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/date> "2021-06-04" .
<https://discovery.ucl.ac.uk/id/document/1358901> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
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<https://discovery.ucl.ac.uk/id/publication/ext-eb9c4beece9a8aec585156e50c2d5b1f> <http://xmlns.com/foaf/0.1/name> "International Journal of Sports Physiology and Performance"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-eb9c4beece9a8aec585156e50c2d5b1f> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/forthcoming> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4e971a55e6ea74a7f852d9202ec27f8d> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-4e971a55e6ea74a7f852d9202ec27f8d> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-16eb4910b5a7a65332a35b9f804d684f> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
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<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-668359721db5a30e895909639b037b1f> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-668359721db5a30e895909639b037b1f> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-453acaf010c2184f7936959d28337e75> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-453acaf010c2184f7936959d28337e75> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ae20babb69a83f81a18eb15f7730c4bb> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-ae20babb69a83f81a18eb15f7730c4bb> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-72f63d19b40ee9c03a78e90630c9a29c> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-72f63d19b40ee9c03a78e90630c9a29c> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7cf921caa1232764c3d799bb03d46f84> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-7cf921caa1232764c3d799bb03d46f84> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-231564d24685143db2a6d09ac0276e32> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-231564d24685143db2a6d09ac0276e32> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ecce86e826bb93071973086c374f6525> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-ecce86e826bb93071973086c374f6525> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-336590bad7e39eb3ce12636404c042b5> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-336590bad7e39eb3ce12636404c042b5> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9c3b64e96abfba1892f11bca334018ba> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-9c3b64e96abfba1892f11bca334018ba> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b6806bdd43628f8dcfbba7d926a016d1> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-b6806bdd43628f8dcfbba7d926a016d1> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7ddc93940da3de07ac501abe68408bcb> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-7ddc93940da3de07ac501abe68408bcb> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3d080cfa58fc1dc9965149f51e998bfe> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_14> <https://discovery.ucl.ac.uk/id/person/ext-3d080cfa58fc1dc9965149f51e998bfe> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e2debc1489e1e47b6b97541420a53142> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_15> <https://discovery.ucl.ac.uk/id/person/ext-e2debc1489e1e47b6b97541420a53142> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-bba01a77f96697944da1969204d6fda0> .
<https://discovery.ucl.ac.uk/id/eprint/10133175> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10133175#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10133175#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_16> <https://discovery.ucl.ac.uk/id/person/ext-bba01a77f96697944da1969204d6fda0> .
<https://discovery.ucl.ac.uk/id/person/ext-7ddc93940da3de07ac501abe68408bcb> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-7ddc93940da3de07ac501abe68408bcb> <http://xmlns.com/foaf/0.1/givenName> "LP"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7ddc93940da3de07ac501abe68408bcb> <http://xmlns.com/foaf/0.1/familyName> "Kilduff"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7ddc93940da3de07ac501abe68408bcb> <http://xmlns.com/foaf/0.1/name> "LP Kilduff"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-453acaf010c2184f7936959d28337e75> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-453acaf010c2184f7936959d28337e75> <http://xmlns.com/foaf/0.1/givenName> "SJ"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-453acaf010c2184f7936959d28337e75> <http://xmlns.com/foaf/0.1/familyName> "Lockey"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-453acaf010c2184f7936959d28337e75> <http://xmlns.com/foaf/0.1/name> "SJ Lockey"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7cf921caa1232764c3d799bb03d46f84> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-7cf921caa1232764c3d799bb03d46f84> <http://xmlns.com/foaf/0.1/givenName> "SH"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7cf921caa1232764c3d799bb03d46f84> <http://xmlns.com/foaf/0.1/familyName> "Day"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7cf921caa1232764c3d799bb03d46f84> <http://xmlns.com/foaf/0.1/name> "SH Day"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9c3b64e96abfba1892f11bca334018ba> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-9c3b64e96abfba1892f11bca334018ba> <http://xmlns.com/foaf/0.1/givenName> "YP"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9c3b64e96abfba1892f11bca334018ba> <http://xmlns.com/foaf/0.1/familyName> "Pitsiladis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9c3b64e96abfba1892f11bca334018ba> <http://xmlns.com/foaf/0.1/name> "YP Pitsiladis"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-72f63d19b40ee9c03a78e90630c9a29c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-72f63d19b40ee9c03a78e90630c9a29c> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-72f63d19b40ee9c03a78e90630c9a29c> <http://xmlns.com/foaf/0.1/familyName> "Callus"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-72f63d19b40ee9c03a78e90630c9a29c> <http://xmlns.com/foaf/0.1/name> "P Callus"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b6806bdd43628f8dcfbba7d926a016d1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-b6806bdd43628f8dcfbba7d926a016d1> <http://xmlns.com/foaf/0.1/givenName> "MA"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b6806bdd43628f8dcfbba7d926a016d1> <http://xmlns.com/foaf/0.1/familyName> "Bennett"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b6806bdd43628f8dcfbba7d926a016d1> <http://xmlns.com/foaf/0.1/name> "MA Bennett"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ecce86e826bb93071973086c374f6525> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ecce86e826bb93071973086c374f6525> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ecce86e826bb93071973086c374f6525> <http://xmlns.com/foaf/0.1/familyName> "Kipps"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ecce86e826bb93071973086c374f6525> <http://xmlns.com/foaf/0.1/name> "C Kipps"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-336590bad7e39eb3ce12636404c042b5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-336590bad7e39eb3ce12636404c042b5> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-336590bad7e39eb3ce12636404c042b5> <http://xmlns.com/foaf/0.1/familyName> "Collins"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-336590bad7e39eb3ce12636404c042b5> <http://xmlns.com/foaf/0.1/name> "M Collins"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e971a55e6ea74a7f852d9202ec27f8d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-4e971a55e6ea74a7f852d9202ec27f8d> <http://xmlns.com/foaf/0.1/givenName> "ECR"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e971a55e6ea74a7f852d9202ec27f8d> <http://xmlns.com/foaf/0.1/familyName> "Hall"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-4e971a55e6ea74a7f852d9202ec27f8d> <http://xmlns.com/foaf/0.1/name> "ECR Hall"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16eb4910b5a7a65332a35b9f804d684f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-16eb4910b5a7a65332a35b9f804d684f> <http://xmlns.com/foaf/0.1/givenName> "SS"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16eb4910b5a7a65332a35b9f804d684f> <http://xmlns.com/foaf/0.1/familyName> "Almeida"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-16eb4910b5a7a65332a35b9f804d684f> <http://xmlns.com/foaf/0.1/name> "SS Almeida"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ae20babb69a83f81a18eb15f7730c4bb> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
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<https://discovery.ucl.ac.uk/id/person/ext-e2debc1489e1e47b6b97541420a53142> <http://xmlns.com/foaf/0.1/givenName> "RM"^^<http://www.w3.org/2001/XMLSchema#string> .
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