eprintid: 10131360 rev_number: 26 eprint_status: archive userid: 608 dir: disk0/10/13/13/60 datestamp: 2021-07-19 13:09:57 lastmod: 2022-06-30 16:30:36 status_changed: 2021-07-19 13:09:57 type: article metadata_visibility: show creators_name: Appleyard, SE creators_name: Larkin, MJW creators_name: Stewart, EM creators_name: Minton, O creators_name: Gilbert, DC title: Digital Medicine in Men with Advanced Prostate Cancer – A Feasibility Study of Electronic Patient-reported Outcomes in Patients on Systemic Treatment ispublished: pub divisions: UCL divisions: B02 divisions: D65 divisions: J38 keywords: Electronic patient-reported outcome measures, patient-reported outcome measures, prostate cancer, quality of life note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: AIMS: Electronic patient-reported outcome (ePRO) measures have the potential to improve patient care, both at an individual level by detecting symptoms and at an organisational level to rationalise follow-up. The introduction of ePROs has many challenges, including funding, institutional rigidity and acceptability for both patients and clinicians. There are multiple examples of successful ePRO programmes but no specific feasibility studies in those who are less digitally engaged. Prostate cancer is predominantly a disease of older men and digital exclusion is associated with increased age. We assessed the feasibility of ePRO completion in older men receiving treatment for advanced prostate cancer both within the clinic and from home. MATERIALS AND METHODS: Men receiving palliative systemic treatment were asked to complete ePROs on a tablet computer in the outpatient department at 0 and 3 months. Participants were also offered optional completion from home. Feasibility was assessed via a mixed methods approach. RESULTS: On-site ePRO completion was acceptable to most patients, with 90% finding it easy or straightforward and 80% preferring electronic over paper. Remote completion was more challenging, even for those who accessed e-mail daily and owned a tablet, with only 20% of participants successfully completing ePROs. Barriers to electronic completion can be categorised as technical, attitudinal and medical. Quality of life and symptom ePRO results were comparable with published data. CONCLUSIONS: On-site completion is achievable in this population with limited staff support. However, remote completion requires further work to improve systems and acceptability for patients. Remote completion is critical to add significantly to current clinical care by detecting symptoms or stratifying follow-up. date: 2021-12-01 date_type: published official_url: https://doi.org/10.1016/j.clon.2021.04.008 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1872482 doi: 10.1016/j.clon.2021.04.008 pii: S0936-6555(21)00157-6 lyricists_name: Gilbert, Duncan lyricists_id: DGILB61 actors_name: Zahnhausen-Stuber, Petra actors_id: PMZAH20 actors_role: owner full_text_status: public publication: Clinical Oncology volume: 33 number: 12 pagerange: 751-760 event_location: England citation: Appleyard, SE; Larkin, MJW; Stewart, EM; Minton, O; Gilbert, DC; (2021) Digital Medicine in Men with Advanced Prostate Cancer – A Feasibility Study of Electronic Patient-reported Outcomes in Patients on Systemic Treatment. Clinical Oncology , 33 (12) pp. 751-760. 10.1016/j.clon.2021.04.008 <https://doi.org/10.1016/j.clon.2021.04.008>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10131360/3/Gilbert_Manuscript%20-%20Digital%20Medicine%20in%20Prostate%20Cancer%20-%20revision.pdf