<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10129328> .
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<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/title> "Seven day pre-analytical stability of serum and plasma neurofilament light chain."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/abstract> "Neurofilament light chain (NfL) has emerged as a biomarker of neuroaxonal damage in several neurologic conditions. With increasing availability of fourth-generation immunoassays detecting NfL in blood, aspects of pre-analytical stability of this biomarker remain unanswered. This study investigated NfL concentrations in serum and plasma samples of 32 patients with neurological diagnoses using state of the art Simoa technology. We tested the effect of delayed freezing of up to 7 days and statistically determined stability and validity of measured concentrations. We found concentrations of NfL in serum and plasma to remain stable at room temperature when processing of samples is delayed up to 7 days (serum: mean absolute difference 0.9 pg/mL, intraindividual variation 1.2%; plasma: mean absolute difference 0.5 pg/mL, intraindividual variation 1.3%). Consistency of these results was nearly perfect for serum and excellent for plasma (intraclass correlation coefficients 0.99 and 0.94, respectively). In conclusion, the soluble serum and plasma NfL concentration remains stable when unprocessed blood samples are stored up to 7 days at room temperature. This information is essential for ensuring reliable study protocols, for example, when shipment of fresh samples is needed."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/date> "2021-05-26" .
<https://discovery.ucl.ac.uk/id/document/1326118> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/volume> "11" .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/issue> "1" .
<https://discovery.ucl.ac.uk/id/publication/ext-cadda8e76e894158e6af9ee5a82f3e8a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-cadda8e76e894158e6af9ee5a82f3e8a> <http://xmlns.com/foaf/0.1/name> "Scientific Reports"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-cadda8e76e894158e6af9ee5a82f3e8a> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f56b21fb21ff26c36589f8b53e63a524> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-f56b21fb21ff26c36589f8b53e63a524> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-101413f11ec73961b27bd3ca0d603716> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-101413f11ec73961b27bd3ca0d603716> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-61c59d60791a71f282a7c69287d96b7f> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-61c59d60791a71f282a7c69287d96b7f> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-478e3230ef034536b23f76e1743f2f02> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-478e3230ef034536b23f76e1743f2f02> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-0dc649fe8036816b074cdfd4dfebf79d> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-0dc649fe8036816b074cdfd4dfebf79d> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c4b196bdd234c39240b6bc5e2579efba> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-c4b196bdd234c39240b6bc5e2579efba> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-8705d8c092a357c3e6e6d455df6f5c4e> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-8705d8c092a357c3e6e6d455df6f5c4e> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ef164b6d22c62698499282fa949042d0> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-ef164b6d22c62698499282fa949042d0> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ad65448fa92468a60da0f255ae90a2a2> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-ad65448fa92468a60da0f255ae90a2a2> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9a12d206833436049b17f1dfa014ecab> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-9a12d206833436049b17f1dfa014ecab> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-068779e03abb9a13503e390ebaf5a8e0> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-068779e03abb9a13503e390ebaf5a8e0> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e965dec47fe39e8c8d913f3ecb1e066a> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10129328#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10129328#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-e965dec47fe39e8c8d913f3ecb1e066a> .
<https://discovery.ucl.ac.uk/id/person/ext-478e3230ef034536b23f76e1743f2f02> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-478e3230ef034536b23f76e1743f2f02> <http://xmlns.com/foaf/0.1/givenName> "H"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-478e3230ef034536b23f76e1743f2f02> <http://xmlns.com/foaf/0.1/familyName> "Haslacher"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-478e3230ef034536b23f76e1743f2f02> <http://xmlns.com/foaf/0.1/name> "H Haslacher"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-101413f11ec73961b27bd3ca0d603716> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-101413f11ec73961b27bd3ca0d603716> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-101413f11ec73961b27bd3ca0d603716> <http://xmlns.com/foaf/0.1/familyName> "Ponleitner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-101413f11ec73961b27bd3ca0d603716> <http://xmlns.com/foaf/0.1/name> "M Ponleitner"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c4b196bdd234c39240b6bc5e2579efba> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-c4b196bdd234c39240b6bc5e2579efba> <http://xmlns.com/foaf/0.1/givenName> "F"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c4b196bdd234c39240b6bc5e2579efba> <http://xmlns.com/foaf/0.1/familyName> "Leutmezer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c4b196bdd234c39240b6bc5e2579efba> <http://xmlns.com/foaf/0.1/name> "F Leutmezer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-068779e03abb9a13503e390ebaf5a8e0> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-068779e03abb9a13503e390ebaf5a8e0> <http://xmlns.com/foaf/0.1/givenName> "H"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-068779e03abb9a13503e390ebaf5a8e0> <http://xmlns.com/foaf/0.1/familyName> "Zetterberg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-068779e03abb9a13503e390ebaf5a8e0> <http://xmlns.com/foaf/0.1/name> "H Zetterberg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f56b21fb21ff26c36589f8b53e63a524> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f56b21fb21ff26c36589f8b53e63a524> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f56b21fb21ff26c36589f8b53e63a524> <http://xmlns.com/foaf/0.1/familyName> "Altmann"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f56b21fb21ff26c36589f8b53e63a524> <http://xmlns.com/foaf/0.1/name> "P Altmann"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-61c59d60791a71f282a7c69287d96b7f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-61c59d60791a71f282a7c69287d96b7f> <http://xmlns.com/foaf/0.1/givenName> "PS"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-61c59d60791a71f282a7c69287d96b7f> <http://xmlns.com/foaf/0.1/familyName> "Rommer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-61c59d60791a71f282a7c69287d96b7f> <http://xmlns.com/foaf/0.1/name> "PS Rommer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9a12d206833436049b17f1dfa014ecab> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-9a12d206833436049b17f1dfa014ecab> <http://xmlns.com/foaf/0.1/givenName> "T"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9a12d206833436049b17f1dfa014ecab> <http://xmlns.com/foaf/0.1/familyName> "Berger"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-9a12d206833436049b17f1dfa014ecab> <http://xmlns.com/foaf/0.1/name> "T Berger"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8705d8c092a357c3e6e6d455df6f5c4e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-8705d8c092a357c3e6e6d455df6f5c4e> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8705d8c092a357c3e6e6d455df6f5c4e> <http://xmlns.com/foaf/0.1/familyName> "Petzold"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-8705d8c092a357c3e6e6d455df6f5c4e> <http://xmlns.com/foaf/0.1/name> "A Petzold"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e965dec47fe39e8c8d913f3ecb1e066a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-e965dec47fe39e8c8d913f3ecb1e066a> <http://xmlns.com/foaf/0.1/givenName> "G"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e965dec47fe39e8c8d913f3ecb1e066a> <http://xmlns.com/foaf/0.1/familyName> "Bsteh"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e965dec47fe39e8c8d913f3ecb1e066a> <http://xmlns.com/foaf/0.1/name> "G Bsteh"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ef164b6d22c62698499282fa949042d0> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ef164b6d22c62698499282fa949042d0> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ef164b6d22c62698499282fa949042d0> <http://xmlns.com/foaf/0.1/familyName> "Wotawa"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ef164b6d22c62698499282fa949042d0> <http://xmlns.com/foaf/0.1/name> "C Wotawa"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ad65448fa92468a60da0f255ae90a2a2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ad65448fa92468a60da0f255ae90a2a2> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ad65448fa92468a60da0f255ae90a2a2> <http://xmlns.com/foaf/0.1/familyName> "Lanzenberger"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ad65448fa92468a60da0f255ae90a2a2> <http://xmlns.com/foaf/0.1/name> "R Lanzenberger"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0dc649fe8036816b074cdfd4dfebf79d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-0dc649fe8036816b074cdfd4dfebf79d> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0dc649fe8036816b074cdfd4dfebf79d> <http://xmlns.com/foaf/0.1/familyName> "Mucher"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-0dc649fe8036816b074cdfd4dfebf79d> <http://xmlns.com/foaf/0.1/name> "P Mucher"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/repository> .
<https://discovery.ucl.ac.uk/id/eprint/10129328> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1326118> .
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