<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10128632> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/title> "Normal adrenal and thyroid function in patients who survive COVID-19 infection"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/abstract> "CONTEXT: The COVID-19 pandemic continues to exert an immense burden on global health services. Moreover, up to 63% of patients experience persistent symptoms, including fatigue, after acute illness. Endocrine systems are vulnerable to the effects of COVID-19 as many glands express the ACE2 receptor, used by the SARS-CoV-2 virion for cellular access. However, the effects of COVID-19 on adrenal and thyroid gland function after acute COVID-19 remain unknown. OBJECTIVES: Our objectives were to evaluate adrenal and thyroid gland function in COVID-19 survivors. DESIGN: A prospective, observational study was undertaken. SETTING: Clinical Research Facility, Imperial College NHS Healthcare Trust. PARTICIPANTS: Seventy patients ≥ 18 years at least 3 months after diagnosis of COVID-19 were included. INTERVENTION: Participants attended a research study visit (08:00-09:30), during which a short Synacthen test (250 µg IV bolus), and thyroid function assessments were performed. RESULTS: All patients had a peak cortisol ≥450 nmol/l after Synacthen, consistent with adequate adrenal reserve. Basal and peak serum cortisol did not differ according to disease severity or history of dexamethasone treatment during COVID-19. There was no difference in baseline or peak cortisol after Synacthen or in thyroid function tests, or thyroid status, in patients with fatigue (n=44) compared to those without (n=26). CONCLUSIONS: Adrenal and thyroid function ≥3 months after presentation with COVID-19 was preserved. Whilst a significant proportion of patients experienced persistent fatigue, their symptoms were not accounted for by alterations in adrenal or thyroid function. These findings have important implications for the clinical care of patients after COVID-19."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/date> "2021-05-19" .
<https://discovery.ucl.ac.uk/id/document/1320653> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/publication/ext-9ceab59279c3af95a499c8a7b00ea41b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-9ceab59279c3af95a499c8a7b00ea41b> <http://xmlns.com/foaf/0.1/name> "Journal of Clinical Endocrinology and Metabolism"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-9ceab59279c3af95a499c8a7b00ea41b> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/forthcoming> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-80ea6e4580e61a09d4b1101f2b2d5e48> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-80ea6e4580e61a09d4b1101f2b2d5e48> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f089e65aea2e9121da41721b2d447187> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-f089e65aea2e9121da41721b2d447187> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c80bd1fe9eb21d30102f14c8d1bd4356> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-c80bd1fe9eb21d30102f14c8d1bd4356> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f826f058e492c64a2d12b10bb9e9dc06> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-f826f058e492c64a2d12b10bb9e9dc06> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-948179d932b7e1d6c103c251d5f7a276> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-948179d932b7e1d6c103c251d5f7a276> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-714d9945505c484503cc7f437c5fffe4> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-714d9945505c484503cc7f437c5fffe4> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-018268e4feb2869e0d8fc89498939387> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-018268e4feb2869e0d8fc89498939387> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-de31cf71308fec6765c2f5d34b1dcaa4> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-de31cf71308fec6765c2f5d34b1dcaa4> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-88d695327a550a34453878ebb60bd1df> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-88d695327a550a34453878ebb60bd1df> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a880e78c3c575dd356dec8656404f71a> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-a880e78c3c575dd356dec8656404f71a> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-325143c5664fe3f5b4e82896c6ca823c> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-325143c5664fe3f5b4e82896c6ca823c> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-86e56f89ba3019196064bc027fcee9f9> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-86e56f89ba3019196064bc027fcee9f9> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d059726068ffa6dcd220f265c218fbc8> .
<https://discovery.ucl.ac.uk/id/eprint/10128632> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10128632#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10128632#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-d059726068ffa6dcd220f265c218fbc8> .
<https://discovery.ucl.ac.uk/id/person/ext-d059726068ffa6dcd220f265c218fbc8> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-d059726068ffa6dcd220f265c218fbc8> <http://xmlns.com/foaf/0.1/givenName> "WS"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d059726068ffa6dcd220f265c218fbc8> <http://xmlns.com/foaf/0.1/familyName> "Dhillo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d059726068ffa6dcd220f265c218fbc8> <http://xmlns.com/foaf/0.1/name> "WS Dhillo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-714d9945505c484503cc7f437c5fffe4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-714d9945505c484503cc7f437c5fffe4> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-714d9945505c484503cc7f437c5fffe4> <http://xmlns.com/foaf/0.1/familyName> "Izzi-Engbeaya"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-714d9945505c484503cc7f437c5fffe4> <http://xmlns.com/foaf/0.1/name> "C Izzi-Engbeaya"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f826f058e492c64a2d12b10bb9e9dc06> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f826f058e492c64a2d12b10bb9e9dc06> <http://xmlns.com/foaf/0.1/givenName> "EG"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f826f058e492c64a2d12b10bb9e9dc06> <http://xmlns.com/foaf/0.1/familyName> "Mills"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f826f058e492c64a2d12b10bb9e9dc06> <http://xmlns.com/foaf/0.1/name> "EG Mills"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-de31cf71308fec6765c2f5d34b1dcaa4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-de31cf71308fec6765c2f5d34b1dcaa4> <http://xmlns.com/foaf/0.1/givenName> "B"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-de31cf71308fec6765c2f5d34b1dcaa4> <http://xmlns.com/foaf/0.1/familyName> "Khoo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-de31cf71308fec6765c2f5d34b1dcaa4> <http://xmlns.com/foaf/0.1/name> "B Khoo"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c80bd1fe9eb21d30102f14c8d1bd4356> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-c80bd1fe9eb21d30102f14c8d1bd4356> <http://xmlns.com/foaf/0.1/givenName> "B"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c80bd1fe9eb21d30102f14c8d1bd4356> <http://xmlns.com/foaf/0.1/familyName> "Patel"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-c80bd1fe9eb21d30102f14c8d1bd4356> <http://xmlns.com/foaf/0.1/name> "B Patel"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f089e65aea2e9121da41721b2d447187> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f089e65aea2e9121da41721b2d447187> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f089e65aea2e9121da41721b2d447187> <http://xmlns.com/foaf/0.1/familyName> "Phylactou"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f089e65aea2e9121da41721b2d447187> <http://xmlns.com/foaf/0.1/name> "M Phylactou"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-948179d932b7e1d6c103c251d5f7a276> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-948179d932b7e1d6c103c251d5f7a276> <http://xmlns.com/foaf/0.1/givenName> "B"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-948179d932b7e1d6c103c251d5f7a276> <http://xmlns.com/foaf/0.1/familyName> "Muzi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-948179d932b7e1d6c103c251d5f7a276> <http://xmlns.com/foaf/0.1/name> "B Muzi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-86e56f89ba3019196064bc027fcee9f9> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-86e56f89ba3019196064bc027fcee9f9> <http://xmlns.com/foaf/0.1/givenName> "T"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-86e56f89ba3019196064bc027fcee9f9> <http://xmlns.com/foaf/0.1/familyName> "Tan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-86e56f89ba3019196064bc027fcee9f9> <http://xmlns.com/foaf/0.1/name> "T Tan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-325143c5664fe3f5b4e82896c6ca823c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-325143c5664fe3f5b4e82896c6ca823c> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-325143c5664fe3f5b4e82896c6ca823c> <http://xmlns.com/foaf/0.1/familyName> "Abbara"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-325143c5664fe3f5b4e82896c6ca823c> <http://xmlns.com/foaf/0.1/name> "A Abbara"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a880e78c3c575dd356dec8656404f71a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-a880e78c3c575dd356dec8656404f71a> <http://xmlns.com/foaf/0.1/givenName> "AN"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a880e78c3c575dd356dec8656404f71a> <http://xmlns.com/foaf/0.1/familyName> "Comninos"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a880e78c3c575dd356dec8656404f71a> <http://xmlns.com/foaf/0.1/name> "AN Comninos"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-88d695327a550a34453878ebb60bd1df> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-88d695327a550a34453878ebb60bd1df> <http://xmlns.com/foaf/0.1/givenName> "K"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-88d695327a550a34453878ebb60bd1df> <http://xmlns.com/foaf/0.1/familyName> "Meeran"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-88d695327a550a34453878ebb60bd1df> <http://xmlns.com/foaf/0.1/name> "K Meeran"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-018268e4feb2869e0d8fc89498939387> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-018268e4feb2869e0d8fc89498939387> <http://xmlns.com/foaf/0.1/givenName> "S"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-018268e4feb2869e0d8fc89498939387> <http://xmlns.com/foaf/0.1/familyName> "Choudhury"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-018268e4feb2869e0d8fc89498939387> <http://xmlns.com/foaf/0.1/name> "S Choudhury"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-80ea6e4580e61a09d4b1101f2b2d5e48> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-80ea6e4580e61a09d4b1101f2b2d5e48> <http://xmlns.com/foaf/0.1/givenName> "SA"^^<http://www.w3.org/2001/XMLSchema#string> .
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