eprintid: 10126943 rev_number: 23 eprint_status: archive userid: 608 dir: disk0/10/12/69/43 datestamp: 2021-04-30 06:32:50 lastmod: 2022-08-23 10:48:59 status_changed: 2021-04-30 06:32:50 type: article metadata_visibility: show creators_name: Papoutsaki, M-V creators_name: Allen, C creators_name: Giganti, F creators_name: Atkinson, D creators_name: Dickinson, L creators_name: Goodman, J creators_name: Saunders, H creators_name: Barrett, T creators_name: Punwani, S title: Standardisation of prostate multiparametric MRI across a hospital network: a London experience. ispublished: pub subjects: UCH divisions: UCL divisions: B02 divisions: C10 divisions: D17 divisions: FI6 divisions: D16 keywords: Clinical protocols, Contrast media, Diffusion, Multiparametric magnetic resonance imaging, Prostatic neoplasms note: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. abstract: OBJECTIVES: National guidelines recommend prostate multiparametric (mp) MRI in men with suspected prostate cancer before biopsy. In this study, we explore prostate mpMRI protocols across 14 London hospitals and determine whether standardisation improves diagnostic quality. METHODS: An MRI physicist facilitated mpMRI set-up across several regional hospitals, working together with experienced uroradiologists who judged diagnostic quality. Radiologists from the 14 hospitals participated in the assessment and optimisation of prostate mpMRI image quality, assessed according to both PiRADSv2 recommendations and on the ability to "rule in" and/or "rule out" prostate cancer. Image quality and sequence parameters of representative mpMRI scans were evaluated across 23 MR scanners. Optimisation visits were performed to improve image quality, and 2 radiologists scored the image quality pre- and post-optimisation. RESULTS: 20/23 mpMRI protocols, consisting of 111 sequences, were optimised by modifying their sequence parameters. Pre-optimisation, only 15% of T2W images were non-diagnostic, whereas 40% of ADC maps, 50% of high b-value DWI and 41% of DCE-MRI were considered non-diagnostic. Post-optimisation, the scores were increased with 80% of ADC maps, 74% of high b-value DWI and 88% of DCE-MRI to be partially or fully diagnostic. T2W sequences were not optimised, due to their higher baseline quality scores. CONCLUSIONS: Targeted intervention at a regional level can improve the diagnostic quality of prostate mpMRI protocols, with implications for improving prostate cancer detection rates and targeted biopsies. date: 2021-04-20 date_type: published official_url: https://doi.org/10.1186/s13244-021-00990-y oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1860446 doi: 10.1186/s13244-021-00990-y pii: 10.1186/s13244-021-00990-y lyricists_name: Atkinson, David lyricists_name: Giganti, Francesco lyricists_name: Papoutsaki, Marianthi-Vasiliki lyricists_name: Punwani, Shonit lyricists_id: DATKI13 lyricists_id: FGIGA51 lyricists_id: MPAPO79 lyricists_id: SPUNW14 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner full_text_status: public publication: Insights Imaging volume: 12 article_number: 52 event_location: Germany citation: Papoutsaki, M-V; Allen, C; Giganti, F; Atkinson, D; Dickinson, L; Goodman, J; Saunders, H; ... Punwani, S; + view all <#> Papoutsaki, M-V; Allen, C; Giganti, F; Atkinson, D; Dickinson, L; Goodman, J; Saunders, H; Barrett, T; Punwani, S; - view fewer <#> (2021) Standardisation of prostate multiparametric MRI across a hospital network: a London experience. Insights Imaging , 12 , Article 52. 10.1186/s13244-021-00990-y <https://doi.org/10.1186/s13244-021-00990-y>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10126943/1/s13244-021-00990-y.pdf