eprintid: 10121838
rev_number: 20
eprint_status: archive
userid: 608
dir: disk0/10/12/18/38
datestamp: 2021-02-17 09:29:32
lastmod: 2021-11-30 23:20:40
status_changed: 2021-02-17 09:29:32
type: article
metadata_visibility: show
creators_name: Picone, DS
creators_name: Schultz, MG
creators_name: Armstrong, MK
creators_name: Black, JA
creators_name: Bos, WJW
creators_name: Chen, C-H
creators_name: Cheng, H-M
creators_name: Cremer, A
creators_name: Dwyer, N
creators_name: Hughes, AD
creators_name: Kim, H-L
creators_name: Lacy, PS
creators_name: Laugesen, E
creators_name: Liang, F
creators_name: Ohte, N
creators_name: Okada, S
creators_name: Omboni, S
creators_name: Ott, C
creators_name: Pereira, T
creators_name: Pucci, G
creators_name: Schmieder, RE
creators_name: Sinha, MD
creators_name: Stouffer, GA
creators_name: Takazawa, K
creators_name: Roberts-Thomson, P
creators_name: Wang, J-G
creators_name: Weber, T
creators_name: Westerhof, BE
creators_name: Williams, B
creators_name: Sharman, JE
creators_name: Invasive Blood Pressure Consortium, 
title: Identifying Isolated Systolic Hypertension From Upper-Arm Cuff Blood Pressure Compared With Invasive Measurements
ispublished: pub
divisions: UCL
divisions: B02
divisions: D14
divisions: GA3
keywords: aorta, blood pressure, coronary angiography, hypertension, prevalence
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: Isolated systolic hypertension (ISH) is the most common form of hypertension and is highly prevalent in older people. We recently showed differences between upper-arm cuff and invasive blood pressure (BP) become greater with increasing age, which could influence correct identification of ISH. This study sought to determine the difference between identification of ISH by cuff BP compared with invasive BP. Cuff BP and invasive aortic BP were measured in 1695 subjects (median 64 years, interquartile range [55-72], 68% male) from the INSPECT (Invasive Blood Pressure Consortium) database. Data were recorded during coronary angiography among 29 studies, using 21 different cuff BP devices. ISH was defined as ≥130/<80 mm Hg using cuff BP compared with invasive aortic BP as the reference. The prevalence of ISH was 24% (n=407) according to cuff BP but 38% (n=642) according to invasive aortic BP. There was fair agreement (Cohen κ, 0.36) and 72% concordance between cuff and invasive aortic BP for identifying ISH. Among the 28% of subjects (n=471) with misclassification of ISH status by cuff BP, 20% (n=96) of the difference was due to lower cuff systolic BP compared with invasive aortic systolic BP (mean, -16.4 mm Hg [95% CI, -18.7 to -14.1]), whereas 49% (n=231) was from higher cuff diastolic BP compared with invasive aortic diastolic BP (+14.2 mm Hg [95% CI, 11.5-16.9]). In conclusion, compared with invasive BP, cuff BP fails to identify ISH in a sizeable portion of older people and demonstrates the need to improve cuff BP measurements.
date: 2021-02
date_type: published
official_url: https://doi.org/10.1161/HYPERTENSIONAHA.120.16109
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1840797
doi: 10.1161/HYPERTENSIONAHA.120.16109
lyricists_name: Hughes, Alun
lyricists_name: Lacy, Peter
lyricists_name: Williams, Bryan
lyricists_id: ADHUG42
lyricists_id: PSLAC83
lyricists_id: BWILL10
actors_name: Lacy, Peter
actors_id: PSLAC83
actors_role: owner
full_text_status: public
publication: Hypertension
volume: 77
number: 2
pagerange: 632-639
event_location: United States
issn: 1524-4563
citation:        Picone, DS;    Schultz, MG;    Armstrong, MK;    Black, JA;    Bos, WJW;    Chen, C-H;    Cheng, H-M;                                                                                                 ... Invasive Blood Pressure Consortium; + view all <#>        Picone, DS;  Schultz, MG;  Armstrong, MK;  Black, JA;  Bos, WJW;  Chen, C-H;  Cheng, H-M;  Cremer, A;  Dwyer, N;  Hughes, AD;  Kim, H-L;  Lacy, PS;  Laugesen, E;  Liang, F;  Ohte, N;  Okada, S;  Omboni, S;  Ott, C;  Pereira, T;  Pucci, G;  Schmieder, RE;  Sinha, MD;  Stouffer, GA;  Takazawa, K;  Roberts-Thomson, P;  Wang, J-G;  Weber, T;  Westerhof, BE;  Williams, B;  Sharman, JE;  Invasive Blood Pressure Consortium;   - view fewer <#>    (2021)    Identifying Isolated Systolic Hypertension From Upper-Arm Cuff Blood Pressure Compared With Invasive Measurements.                   Hypertension , 77  (2)   pp. 632-639.    10.1161/HYPERTENSIONAHA.120.16109 <https://doi.org/10.1161/HYPERTENSIONAHA.120.16109>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10121838/1/389546_0_merged_1596633119.pdf