eprintid: 10120496
rev_number: 12
eprint_status: archive
userid: 608
dir: disk0/10/12/04/96
datestamp: 2021-02-03 14:23:00
lastmod: 2021-02-03 14:23:00
status_changed: 2021-02-03 14:23:00
type: article
metadata_visibility: show
creators_name: Saso, S
creators_name: Clancy, NT
creators_name: Jones, BP
creators_name: Bracewell-Milnes, T
creators_name: Al-Memar, M
creators_name: Cannon, EM
creators_name: Ahluwalia, S
creators_name: Yazbek, J
creators_name: Thum, M-Y
creators_name: Bourne, T
creators_name: Elson, DS
creators_name: Smith, JR
creators_name: Ghaem-Maghami, S
title: Use of biomedical photonics in gynecological surgery: a uterine transplantation model
ispublished: pub
divisions: UCL
divisions: A01
divisions: B04
divisions: C05
divisions: F42
keywords: optical imaging, oxygen saturation, surgical imaging, tissue perfusion, uterine transplantation
note: This work is licensed under the Creative Commons Attribution 4.0 License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
abstract: Aim: Uterine transplantation (UTx) has been proposed as a treatment for permanent absolute uterine factor infertility. The study aims were to compare pulse oximetry and multispectral imaging (MSI), for intraoperative tracking of uterine oxygen saturation in animal UTx models (rabbit and sheep). Results/methodology: Imaging results confirmed the re-establishment of adequate perfusion in the transplanted organ after surgery. Comparison of oxygen saturation values between the pre-UTx donor and post-UTx recipient, and pre-UTx and post-UTx recipient reveals a statistically significant decrease in saturation levels post-UTx. Conclusion: The use of MSI is the first case in gynecology and has demonstrated promise of possible future human use. MSI technique has advantages over pulse oximetry – it provides spatial information in a real-time, noncontact manner.
date: 2018-04
date_type: published
publisher: Future Science Ltd
official_url: https://doi.org/10.4155/fsoa-2017-0129
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1844495
doi: 10.4155/fsoa-2017-0129
lyricists_name: Clancy, Neil
lyricists_id: NCLAN93
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
full_text_status: public
publication: Future Science OA
volume: 4
number: 4
article_number: FSO286
citation:        Saso, S;    Clancy, NT;    Jones, BP;    Bracewell-Milnes, T;    Al-Memar, M;    Cannon, EM;    Ahluwalia, S;                         ... Ghaem-Maghami, S; + view all <#>        Saso, S;  Clancy, NT;  Jones, BP;  Bracewell-Milnes, T;  Al-Memar, M;  Cannon, EM;  Ahluwalia, S;  Yazbek, J;  Thum, M-Y;  Bourne, T;  Elson, DS;  Smith, JR;  Ghaem-Maghami, S;   - view fewer <#>    (2018)    Use of biomedical photonics in gynecological surgery: a uterine transplantation model.                   Future Science OA , 4  (4)    , Article FSO286.  10.4155/fsoa-2017-0129 <https://doi.org/10.4155/fsoa-2017-0129>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10120496/1/fsoa-2017-0129.pdf