<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10120487> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/title> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/abstract> "BACKGROUND AND PURPOSE: Cannabidiol (CBD) has been shown to differentially regulate the mechanistic target of rapamycin complex 1 (mTORC1) in preclinical models of disease, where it reduces activity in models of epilepsies and cancer and increases it in models of multiple sclerosis (MS) and psychosis. Here, we investigate the effects of phytocannabinoids on mTORC1 and define a molecular mechanism. EXPERIMENTAL APPROACH: A novel mechanism for phytocannabinoids was identified using the tractable model system, Dictyostelium discoideum. Using mouse embryonic fibroblasts, we further validate this new mechanism of action. We demonstrate clinical relevance using cells derived from healthy individuals and from people with MS (pwMS). KEY RESULTS: Both CBD and the more abundant cannabigerol (CBG) enhance mTORC1 activity in D. discoideum. We identify a mechanism for this effect involving inositol polyphosphate multikinase (IPMK), where elevated IPMK expression reverses the response to phytocannabinoids, decreasing mTORC1 activity upon treatment, providing new insight on phytocannabinoids' actions. We further validated this mechanism using mouse embryonic fibroblasts. Clinical relevance of this effect was shown in primary human peripheral blood mononuclear cells, where CBD and CBG treatment increased mTORC1 activity in cells derived from healthy individuals and decreased mTORC1 activity in cells derived from pwMS. CONCLUSION AND IMPLICATIONS: Our findings suggest that both CBD and the abundant CBG differentially regulate mTORC1 signalling through a mechanism dependent on the activity of the upstream IPMK signalling pathway, with potential relevance to the treatment of mTOR-related disorders, including MS."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/date> "2020-12-21" .
<https://discovery.ucl.ac.uk/id/document/1257192> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/publication/ext-ff98f0c0f27a0d5465347c4c305d1252> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-ff98f0c0f27a0d5465347c4c305d1252> <http://xmlns.com/foaf/0.1/name> "British Journal of Pharmacology"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-ff98f0c0f27a0d5465347c4c305d1252> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/forthcoming> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-048efcd31c5d86d16e41176a82d463cd> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-048efcd31c5d86d16e41176a82d463cd> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-95d94e2b5a0bc0d33c3a29dc7b61cd07> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-95d94e2b5a0bc0d33c3a29dc7b61cd07> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ddfeb3922ed1b1c11b32a7026c671508> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-ddfeb3922ed1b1c11b32a7026c671508> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7099d6eb9b0be8eba48c505f5d4392ce> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-7099d6eb9b0be8eba48c505f5d4392ce> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f6c46c1537d3e5f7cba15ee0c2dc5984> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-f6c46c1537d3e5f7cba15ee0c2dc5984> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-21fc309ea7fa6bc6385d3223f7c8cc9a> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-21fc309ea7fa6bc6385d3223f7c8cc9a> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f8d83abeb4eae06351c083e600f49641> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-f8d83abeb4eae06351c083e600f49641> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3ed15878efc74e338806f17159049e0a> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-3ed15878efc74e338806f17159049e0a> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-797bf46cd3d72b657f8445518a3115fa> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-797bf46cd3d72b657f8445518a3115fa> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e400c768727644c72f83100aca5f3874> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-e400c768727644c72f83100aca5f3874> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-849e7766755c475c02358f17bcd05235> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10120487#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10120487#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-849e7766755c475c02358f17bcd05235> .
<https://discovery.ucl.ac.uk/id/person/ext-e400c768727644c72f83100aca5f3874> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-e400c768727644c72f83100aca5f3874> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e400c768727644c72f83100aca5f3874> <http://xmlns.com/foaf/0.1/familyName> "Saiardi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-e400c768727644c72f83100aca5f3874> <http://xmlns.com/foaf/0.1/name> "A Saiardi"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfeb3922ed1b1c11b32a7026c671508> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfeb3922ed1b1c11b32a7026c671508> <http://xmlns.com/foaf/0.1/givenName> "CJ"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfeb3922ed1b1c11b32a7026c671508> <http://xmlns.com/foaf/0.1/familyName> "Perry"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ddfeb3922ed1b1c11b32a7026c671508> <http://xmlns.com/foaf/0.1/name> "CJ Perry"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-797bf46cd3d72b657f8445518a3115fa> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-797bf46cd3d72b657f8445518a3115fa> <http://xmlns.com/foaf/0.1/givenName> "EJ"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-797bf46cd3d72b657f8445518a3115fa> <http://xmlns.com/foaf/0.1/familyName> "Downer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-797bf46cd3d72b657f8445518a3115fa> <http://xmlns.com/foaf/0.1/name> "EJ Downer"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-849e7766755c475c02358f17bcd05235> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-849e7766755c475c02358f17bcd05235> <http://xmlns.com/foaf/0.1/givenName> "RSB"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-849e7766755c475c02358f17bcd05235> <http://xmlns.com/foaf/0.1/familyName> "Williams"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-849e7766755c475c02358f17bcd05235> <http://xmlns.com/foaf/0.1/name> "RSB Williams"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3ed15878efc74e338806f17159049e0a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-3ed15878efc74e338806f17159049e0a> <http://xmlns.com/foaf/0.1/givenName> "W"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3ed15878efc74e338806f17159049e0a> <http://xmlns.com/foaf/0.1/familyName> "Hind"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-3ed15878efc74e338806f17159049e0a> <http://xmlns.com/foaf/0.1/name> "W Hind"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-048efcd31c5d86d16e41176a82d463cd> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-048efcd31c5d86d16e41176a82d463cd> <http://xmlns.com/foaf/0.1/givenName> "JL"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-048efcd31c5d86d16e41176a82d463cd> <http://xmlns.com/foaf/0.1/familyName> "Damstra-Oddy"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-048efcd31c5d86d16e41176a82d463cd> <http://xmlns.com/foaf/0.1/name> "JL Damstra-Oddy"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f8d83abeb4eae06351c083e600f49641> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f8d83abeb4eae06351c083e600f49641> <http://xmlns.com/foaf/0.1/givenName> "L"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f8d83abeb4eae06351c083e600f49641> <http://xmlns.com/foaf/0.1/familyName> "Costelloe"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f8d83abeb4eae06351c083e600f49641> <http://xmlns.com/foaf/0.1/name> "L Costelloe"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-21fc309ea7fa6bc6385d3223f7c8cc9a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-21fc309ea7fa6bc6385d3223f7c8cc9a> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-21fc309ea7fa6bc6385d3223f7c8cc9a> <http://xmlns.com/foaf/0.1/familyName> "Schaf"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-21fc309ea7fa6bc6385d3223f7c8cc9a> <http://xmlns.com/foaf/0.1/name> "J Schaf"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-95d94e2b5a0bc0d33c3a29dc7b61cd07> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-95d94e2b5a0bc0d33c3a29dc7b61cd07> <http://xmlns.com/foaf/0.1/givenName> "EC"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-95d94e2b5a0bc0d33c3a29dc7b61cd07> <http://xmlns.com/foaf/0.1/familyName> "Warren"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-95d94e2b5a0bc0d33c3a29dc7b61cd07> <http://xmlns.com/foaf/0.1/name> "EC Warren"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f6c46c1537d3e5f7cba15ee0c2dc5984> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-f6c46c1537d3e5f7cba15ee0c2dc5984> <http://xmlns.com/foaf/0.1/givenName> "J-MK"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f6c46c1537d3e5f7cba15ee0c2dc5984> <http://xmlns.com/foaf/0.1/familyName> "Fitzpatrick"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-f6c46c1537d3e5f7cba15ee0c2dc5984> <http://xmlns.com/foaf/0.1/name> "J-MK Fitzpatrick"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7099d6eb9b0be8eba48c505f5d4392ce> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-7099d6eb9b0be8eba48c505f5d4392ce> <http://xmlns.com/foaf/0.1/givenName> "Y"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7099d6eb9b0be8eba48c505f5d4392ce> <http://xmlns.com/foaf/0.1/familyName> "Desfougères"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-7099d6eb9b0be8eba48c505f5d4392ce> <http://xmlns.com/foaf/0.1/name> "Y Desfougères"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/repository> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257192> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/1257192> <http://www.w3.org/2000/01/rdf-schema#label> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity (Text)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://purl.org/dc/elements/1.1/hasVersion> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasPublished> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257192> <http://eprints.org/ontology/hasFile> <https://discovery.ucl.ac.uk/id/eprint/10120487/1/bph.15351.pdf> .
<https://discovery.ucl.ac.uk/id/document/1257192> <http://purl.org/dc/terms/hasPart> <https://discovery.ucl.ac.uk/id/eprint/10120487/1/bph.15351.pdf> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/1/bph.15351.pdf> <http://www.w3.org/2000/01/rdf-schema#label> "bph.15351.pdf"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1257193> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://www.w3.org/2000/01/rdf-schema#label> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://eprints.org/relation/isVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://eprints.org/relation/islightboxThumbnailVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://eprints.org/ontology/hasFile> <https://discovery.ucl.ac.uk/id/eprint/10120487/2/lightbox.jpg> .
<https://discovery.ucl.ac.uk/id/document/1257193> <http://purl.org/dc/terms/hasPart> <https://discovery.ucl.ac.uk/id/eprint/10120487/2/lightbox.jpg> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/2/lightbox.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "lightbox.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1257194> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://www.w3.org/2000/01/rdf-schema#label> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://eprints.org/relation/isVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://eprints.org/relation/ispreviewThumbnailVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://eprints.org/ontology/hasFile> <https://discovery.ucl.ac.uk/id/eprint/10120487/3/preview.jpg> .
<https://discovery.ucl.ac.uk/id/document/1257194> <http://purl.org/dc/terms/hasPart> <https://discovery.ucl.ac.uk/id/eprint/10120487/3/preview.jpg> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/3/preview.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "preview.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1257195> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://www.w3.org/2000/01/rdf-schema#label> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://eprints.org/relation/isVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://eprints.org/relation/ismediumThumbnailVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://eprints.org/ontology/hasFile> <https://discovery.ucl.ac.uk/id/eprint/10120487/4/medium.jpg> .
<https://discovery.ucl.ac.uk/id/document/1257195> <http://purl.org/dc/terms/hasPart> <https://discovery.ucl.ac.uk/id/eprint/10120487/4/medium.jpg> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/4/medium.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "medium.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1257196> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://www.w3.org/2000/01/rdf-schema#label> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://eprints.org/relation/isVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://eprints.org/relation/issmallThumbnailVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://eprints.org/ontology/hasFile> <https://discovery.ucl.ac.uk/id/eprint/10120487/5/small.jpg> .
<https://discovery.ucl.ac.uk/id/document/1257196> <http://purl.org/dc/terms/hasPart> <https://discovery.ucl.ac.uk/id/eprint/10120487/5/small.jpg> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/5/small.jpg> <http://www.w3.org/2000/01/rdf-schema#label> "small.jpg"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://eprints.org/ontology/hasDocument> <https://discovery.ucl.ac.uk/id/document/1257197> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/Document> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://www.w3.org/2000/01/rdf-schema#label> "Phytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity (Other)"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://eprints.org/relation/isVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://eprints.org/relation/isVolatileVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://eprints.org/relation/isIndexCodesVersionOf> <https://discovery.ucl.ac.uk/id/document/1257192> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://eprints.org/ontology/hasFile> <https://discovery.ucl.ac.uk/id/eprint/10120487/6/indexcodes.txt> .
<https://discovery.ucl.ac.uk/id/document/1257197> <http://purl.org/dc/terms/hasPart> <https://discovery.ucl.ac.uk/id/eprint/10120487/6/indexcodes.txt> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/6/indexcodes.txt> <http://www.w3.org/2000/01/rdf-schema#label> "indexcodes.txt"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10120487> <http://www.w3.org/2000/01/rdf-schema#seeAlso> <https://discovery.ucl.ac.uk/id/eprint/10120487/> .
<https://discovery.ucl.ac.uk/id/eprint/10120487/> <http://purl.org/dc/elements/1.1/title> "HTML Summary of #10120487 \n\nPhytocannabinoid-dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity\n\n" .
<https://discovery.ucl.ac.uk/id/eprint/10120487/> <http://purl.org/dc/elements/1.1/format> "text/html" .
<https://discovery.ucl.ac.uk/id/eprint/10120487/> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10120487> .