eprintid: 10117079
rev_number: 15
eprint_status: archive
userid: 608
dir: disk0/10/11/70/79
datestamp: 2020-12-14 16:06:43
lastmod: 2021-10-10 23:20:51
status_changed: 2020-12-14 16:06:43
type: article
metadata_visibility: show
creators_name: Ng, VWS
creators_name: Siu, C-W
creators_name: Chiu, PKC
creators_name: Kng, CPL
creators_name: Jamieson, E
creators_name: Wong, ICK
creators_name: Lam, MPS
title: Understanding the barriers to using oral anticoagulants among long-term aspirin users with atrial fibrillation - a qualitative study
ispublished: pub
divisions: UCL
divisions: B02
divisions: C08
divisions: D10
divisions: G11
keywords: Aspirin, Atrial fibrillation, Barriers, Oral anticoagulants
note: © 2020 BioMed Central Ltd. This article is licensed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/).
abstract: BACKGROUND: Despite international treatment guidelines currently advocating oral anticoagulants (OACs) as the only appropriate stroke prevention therapy for patients with atrial fibrillation (AF) and evidence that OACs can greatly reduce the risk of stroke with similar risk of bleeding compared with aspirin, the underuse of OACs in patients with AF is common globally, especially in Asia. This study aimed to identify the barriers to prescribing and using OACs among long-term aspirin users with AF. METHOD: Face-to-face interviews were conducted with fourteen eligible patients with AF using a semi-structured interview guide. The interview recordings were transcribed verbatim and data was analyzed according to the principles of thematic analysis. RESULTS: Five themes were developed: awareness of AF symptoms and diagnosis; knowledge and understanding of AF and stroke prevention therapy; role of decision-making in prescribing; willingness to switch from aspirin to OACs; and impact of OAC regimen on daily living. The majority of the patients were not aware of the symptoms and diagnosis of AF and only had a vague understanding of the illness and stroke prevention therapy, leading to their minimal involvement in decisions relating to their treatment. Some patients and their caregivers were particularly concerned about the bleeding complications from OACs and perceived aspirin to be a suitable alternative as they find the adverse effects from aspirin manageable and so preferred to remain on aspirin if switching to OACs was not compulsory. Lastly, the lifestyle modifications required when using warfarin, e.g. alternative dosing regimen, diet restriction, were seen as barriers to some patients and caregivers. CONCLUSION: The findings revealed patients' knowledge gap in AF management which may be targeted using educational interventions to improve patients' understanding of AF and its management and hence encourage active participation in the decision-making of their treatment in the future.
date: 2020
date_type: published
official_url: https://doi.org/10.1186/s12913-020-05947-3
oa_status: green
full_text_type: pub
pmcid: PMC7691100
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1834001
doi: 10.1186/s12913-020-05947-3
pii: 10.1186/s12913-020-05947-3
lyricists_name: Jamieson, Elizabeth
lyricists_name: Wong, Ian
lyricists_id: EJAMI89
lyricists_id: ICKWO00
actors_name: Flynn, Bernadette
actors_id: BFFLY94
actors_role: owner
full_text_status: public
publication: BMC Health Services Research
volume: 20
number: 1
article_number: 1084
event_location: England
citation:        Ng, VWS;    Siu, C-W;    Chiu, PKC;    Kng, CPL;    Jamieson, E;    Wong, ICK;    Lam, MPS;      (2020)    Understanding the barriers to using oral anticoagulants among long-term aspirin users with atrial fibrillation - a qualitative study.                   BMC Health Services Research , 20  (1)    , Article 1084.  10.1186/s12913-020-05947-3 <https://doi.org/10.1186/s12913-020-05947-3>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10117079/1/s12913-020-05947-3.pdf