@article{discovery10114919,
         journal = {Pediatric Nephrology},
           pages = {2165--2175},
            year = {2021},
           title = {Novel insights in the genetics of steroid-sensitive nephrotic syndrome in childhood},
            note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.},
           month = {August},
          volume = {36},
        keywords = {CALHM6, GWAS, Genetics, HLA, Paediatrics, SSNS, Steroid-sensitive nephrotic syndrome},
        abstract = {Steroid-sensitive nephrotic syndrome (SSNS) is the most common form of nephrotic syndrome in childhood and there is growing evidence that genetics play a role in the susceptibility for the disease. Familial clustering has been observed and has�led to several studies on familial SSNS trying to identify a monogenic cause of the disease. Until now, however, none of these have provided convincing evidence for Mendelian inheritance. This and the phenotypic variability within SSNS suggest a complex inheritance pattern, where multiple variants and interactions between those and the environment play roles in disease development. Genome-wide association studies (GWASs) have been used to investigate this complex disease. We herein highlight new insights in the genetics of the disease provided by GWAS and identify�how these�insights fit into our understanding of the pathogenesis of SSNS.},
          author = {Dufek-Kamperis, S and Kleta, R and Bockenhauer, D and Gale, D and Downie, ML},
             url = {http://dx.doi.org/10.1007/s00467-020-04780-4}
}