TY  - JOUR
UR  - https://doi.org/10.1016/j.conb.2020.08.010
SP  - 27
TI  - Cortico-cerebellar interactions during goal-directed behavior
N1  - This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
ID  - discovery10112715
AV  - public
EP  - 37
JF  - Current Opinion in Neurobiology
N2  - Preparatory activity is observed across multiple interconnected brain regions before goal-directed movement. Preparatory activity reflects discrete activity states representing specific future actions. It is unclear how this activity is mediated by multi-regional interactions. Recent evidence suggests that the cerebellum, classically associated with fine motor control, contributes to preparatory activity in the neocortex. We review recent advances and offer perspective on the function of cortico-cerebellar interactions during goal-directed behavior. We propose that the cerebellum learns to facilitate transitions between neocortical activity states. Transitions between activity states enable flexible and appropriately timed behavioral responses.
VL  - 65
A1  - Li, N
A1  - Mrsic-Flogel, TD
Y1  - 2020/12//
ER  -