eprintid: 10112054
rev_number: 19
eprint_status: archive
userid: 608
dir: disk0/10/11/20/54
datestamp: 2020-10-14 10:18:01
lastmod: 2021-12-17 11:34:20
status_changed: 2020-10-14 10:18:01
type: article
metadata_visibility: show
creators_name: Berke Göztepe, M
creators_name: Görkem Özyurt, M
creators_name: Sitki Türker, K
creators_name: Uysal, H
title: Comparison of the temporal properties of medium latency responses induced by cortical and peripheral stimulation
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F85
keywords: transcranial magnetic stimulation, medium latency reflex, motor evoked potential, spinal circuits, reflexes
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
abstract: Sudden foot dorsiflexion lengthens soleus muscle and activates stretch-based spinal reflexes. Dorsiflexion can be triggered by activating tibialis anterior (TA) muscle through peroneal nerve stimulation or transcranial magnetic stimulation (TMS) which evokes a response in the soleus muscle referred to as Medium Latency Reflex (MLR) or motor-evoked potential-80 (Soleus MEP80), respectively. This study aimed to examine the relationship between these responses in humans. Therefore, latency characteristics and correlation of responses between soleus MEP80 and MLR were investigated. We have also calculated the latencies from the onset of tibialis activity, i.e., subtracting of TA-MEP from MEP80 and TA direct motor response from MLR. We referred to these calculations as Stretch Loop Latency Central (SLLc) for MEP80 and Stretch Loop Latency Peripheral (SLLp) for MLR. The latency of SLLc was found to be 61.4 ± 5.6 ms which was significantly shorter (P = 0.0259) than SLLp (64.0 ± 4.2 ms) and these latencies were correlated (P = 0.0045, r = 0.689). The latency of both responses was also found to be inversely related to the response amplitude (P = 0.0121, r = 0.451) probably due to the activation of large motor units. When amplitude differences were corrected, i.e. investigating the responses with similar amplitudes, SLLp, and SLLc latencies found to be similar (P = 0.1317). Due to the identical features of the soleus MEP80 and MLR, we propose that they may both have spinal origins.
date: 2020-12
date_type: published
publisher: Elsevier BV
official_url: https://doi.org/10.1016/j.jelekin.2020.102477
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1821030
doi: 10.1016/j.jelekin.2020.102477
lyricists_name: Ozyurt, Mustafa
lyricists_id: MGOZY54
actors_name: Ozyurt, Mustafa
actors_id: MGOZY54
actors_role: owner
full_text_status: public
publication: Journal of Electromyography and Kinesiology
volume: 55
article_number: 102477
citation:        Berke Göztepe, M;    Görkem Özyurt, M;    Sitki Türker, K;    Uysal, H;      (2020)    Comparison of the temporal properties of medium latency responses induced by cortical and peripheral stimulation.                   Journal of Electromyography and Kinesiology , 55     , Article 102477.  10.1016/j.jelekin.2020.102477 <https://doi.org/10.1016/j.jelekin.2020.102477>.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10112054/1/10.1016%40j.jelekin.2020.102477.pdf