<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> . <> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10111408> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/title> "Seroprevalence of SARS-CoV-2 antibodies in people with an acute loss in their sense of smell and/or taste in a community-based population in London, UK: An observational cohort study"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/abstract> "BACKGROUND: Loss of smell and taste are commonly reported symptoms associated with coronavirus disease 2019 (COVID-19); however, the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in people with acute loss of smell and/or taste is unknown. The study aimed to determine the seroprevalence of SARS-CoV-2 antibodies in a community-based population with acute loss of smell and/or taste and to compare the frequency of COVID-19 associated symptoms in participants with and without SARS-CoV-2 antibodies. It also evaluated whether smell or taste loss are indicative of COVID-19 infection. METHODS AND FINDINGS: Text messages, sent via primary care centers in London, United Kingdom, invited people with loss of smell and/or taste in the preceding month, to participate. Recruitment took place between 23 April 2020 and 14 May 2020. A total of 590 participants enrolled via a web-based platform and responded to questions about loss of smell and taste and other COVID-19-related symptoms. Mean age was 39.4 years (SD ± 12.0) and 69.1% (n = 392) of participants were female. A total of 567 (96.1%) had a telemedicine consultation during which their COVID-19-related symptoms were verified and a lateral flow immunoassay test that detected SARS-CoV-2 immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies was undertaken under medical supervision. A total of 77.6% of 567 participants with acute smell and/or taste loss had SARS-CoV-2 antibodies; of these, 39.8% (n = 175) had neither cough nor fever. New loss of smell was more prevalent in participants with SARS-CoV-2 antibodies, compared with those without antibodies (93.4% versus 78.7%, p < 0.001), whereas taste loss was equally prevalent (90.2% versus 89.0%, p = 0.738). Seropositivity for SARS-CoV-2 was 3 times more likely in participants with smell loss (OR 2.86; 95% CI 1.27-6.36; p < 0.001) compared with those with taste loss. The limitations of this study are the lack of a general population control group, the self-reported nature of the smell and taste changes, and the fact our methodology does not take into account the possibility that a population subset may not seroconvert to develop SARS-CoV-2 antibodies post-COVID-19. CONCLUSIONS: Our findings suggest that recent loss of smell is a highly specific COVID-19 symptom and should be considered more generally in guiding case isolation, testing, and treatment of COVID-19. TRIALS REGISTRATION: ClinicalTrials.gov NCT04377815."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/date> "2020-10-01" . <https://discovery.ucl.ac.uk/id/document/1186486> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/volume> "17" . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/issue> "10" . <https://discovery.ucl.ac.uk/id/publication/ext-37fc89c3fd76f5573aa28ac7b38046e5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> . <https://discovery.ucl.ac.uk/id/publication/ext-37fc89c3fd76f5573aa28ac7b38046e5> <http://xmlns.com/foaf/0.1/name> "PLOS Medicine"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-37fc89c3fd76f5573aa28ac7b38046e5> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-6a96a45211d8590c4e7eb8d15eb06c1f> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-6a96a45211d8590c4e7eb8d15eb06c1f> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-42c19456674d5fd95466671907b27cca> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-42c19456674d5fd95466671907b27cca> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e906e53802d6c5900c509c47aa2ec17d> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-e906e53802d6c5900c509c47aa2ec17d> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-daeda454e9bf41581bacc4465a8cd077> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-daeda454e9bf41581bacc4465a8cd077> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d513e04e898206ac5d5c7364a5f87bb6> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-d513e04e898206ac5d5c7364a5f87bb6> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-fb59af1149321785f51370211adea7c1> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-fb59af1149321785f51370211adea7c1> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-28c7e21ccb3fb916f8365461a9786ff4> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> . <https://discovery.ucl.ac.uk/id/eprint/10111408#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-28c7e21ccb3fb916f8365461a9786ff4> . <https://discovery.ucl.ac.uk/id/person/ext-6a96a45211d8590c4e7eb8d15eb06c1f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-6a96a45211d8590c4e7eb8d15eb06c1f> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-6a96a45211d8590c4e7eb8d15eb06c1f> <http://xmlns.com/foaf/0.1/familyName> "Makaronidis"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-6a96a45211d8590c4e7eb8d15eb06c1f> <http://xmlns.com/foaf/0.1/name> "J Makaronidis"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d513e04e898206ac5d5c7364a5f87bb6> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-d513e04e898206ac5d5c7364a5f87bb6> <http://xmlns.com/foaf/0.1/givenName> "RZ"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d513e04e898206ac5d5c7364a5f87bb6> <http://xmlns.com/foaf/0.1/familyName> "Omar"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d513e04e898206ac5d5c7364a5f87bb6> <http://xmlns.com/foaf/0.1/name> "RZ Omar"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-42c19456674d5fd95466671907b27cca> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-42c19456674d5fd95466671907b27cca> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-42c19456674d5fd95466671907b27cca> <http://xmlns.com/foaf/0.1/familyName> "Mok"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-42c19456674d5fd95466671907b27cca> <http://xmlns.com/foaf/0.1/name> "J Mok"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-fb59af1149321785f51370211adea7c1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-fb59af1149321785f51370211adea7c1> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-fb59af1149321785f51370211adea7c1> <http://xmlns.com/foaf/0.1/familyName> "Carnemolla"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-fb59af1149321785f51370211adea7c1> <http://xmlns.com/foaf/0.1/name> "A Carnemolla"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e906e53802d6c5900c509c47aa2ec17d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-e906e53802d6c5900c509c47aa2ec17d> <http://xmlns.com/foaf/0.1/givenName> "N"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e906e53802d6c5900c509c47aa2ec17d> <http://xmlns.com/foaf/0.1/familyName> 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<http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-daeda454e9bf41581bacc4465a8cd077> <http://xmlns.com/foaf/0.1/givenName> "CG"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-daeda454e9bf41581bacc4465a8cd077> <http://xmlns.com/foaf/0.1/familyName> "Magee"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-daeda454e9bf41581bacc4465a8cd077> <http://xmlns.com/foaf/0.1/name> "CG Magee"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/EPrint> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://eprints.org/ontology/ArticleEPrint> . <https://discovery.ucl.ac.uk/id/eprint/10111408> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/repository> . 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