<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> . <> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10110561> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/title> "Population-based blood screening for pre-clinical Alzheimer's disease in a British birth cohort at age 70"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/abstract> "Alzheimer’s disease has a preclinical stage when cerebral amyloid-β deposition occurs before symptoms emerge, and when amyloid-β-targeted therapies may have maximum benefits. Existing amyloid-β status measurement techniques, including amyloid PET and CSF testing, are difficult to deploy at scale, so blood biomarkers are increasingly considered for screening. We compared three different blood-based techniques—liquid chromatography-mass spectrometry measures of plasma amyloid-β, and single molecule array (Simoa) measures of plasma amyloid-β and phospho-tau181—to detect cortical 18F-florbetapir amyloid PET positivity (defined as a standardized uptake value ratio of >0.61 between a predefined cortical region of interest and eroded subcortical white matter) in dementia-free members of Insight 46, a substudy of the population-based British 1946 birth cohort. We used logistic regression models with blood biomarkers as predictors of amyloid PET status, with or without age, sex and APOE ε4 carrier status as covariates. We generated receiver operating characteristics curves and quantified areas under the curves to compare the concordance of the different blood tests with amyloid PET. We determined blood test cut-off points using Youden’s index, then estimated numbers needed to screen to obtain 100 amyloid PET-positive individuals. Of the 502 individuals assessed, 441 dementia-free individuals with complete data were included; 82 (18.6%) were amyloid PET-positive. The area under the curve for amyloid PET status using a base model comprising age, sex and APOE ε4 carrier status was 0.695 (95% confidence interval: 0.628–0.762). The two best-performing Simoa plasma biomarkers were amyloid-β42/40 (0.620; 0.548–0.691) and phospho-tau181 (0.707; 0.646–0.768), but neither outperformed the base model. Mass spectrometry plasma measures performed significantly better than any other measure (amyloid-β1-42/1-40: 0.817; 0.770–0.864 and amyloid-β composite: 0.820; 0.775–0.866). At a cut-off point of 0.095, mass spectrometry measures of amyloid-β1-42/1-40 detected amyloid PET positivity with 86.6% sensitivity and 71.9% specificity. Without screening, to obtain 100 PET-positive individuals from a population with similar amyloid PET positivity prevalence to Insight 46, 543 PET scans would need to be performed. Screening using age, sex and APOE ε4 status would require 940 individuals, of whom 266 would proceed to scan. Using mass spectrometry amyloid-β1-42/1-40 alone would reduce these numbers to 623 individuals and 243 individuals, respectively. Across a theoretical range of amyloid PET positivity prevalence of 10–50%, mass spectrometry measures of amyloid-β1-42/1-40 would consistently reduce the numbers proceeding to scans, with greater cost savings demonstrated at lower prevalence."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/date> "2021-02" . <https://discovery.ucl.ac.uk/id/document/1305282> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/volume> "144" . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/issue> "2" . <https://discovery.ucl.ac.uk/id/org/ext-daeb92daf570917684167066877da0ed> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> . <https://discovery.ucl.ac.uk/id/org/ext-daeb92daf570917684167066877da0ed> <http://xmlns.com/foaf/0.1/name> "Oxford University Press (OUP)"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/publisher> <https://discovery.ucl.ac.uk/id/org/ext-daeb92daf570917684167066877da0ed> . <https://discovery.ucl.ac.uk/id/publication/ext-79479f886e3748ba7af78ddff2d1a3de> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> . <https://discovery.ucl.ac.uk/id/publication/ext-79479f886e3748ba7af78ddff2d1a3de> <http://xmlns.com/foaf/0.1/name> "Brain"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-79479f886e3748ba7af78ddff2d1a3de> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4f7de2f74386cfdfc2bd124acfb498c5> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-4f7de2f74386cfdfc2bd124acfb498c5> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-df752480adeca23f8ebea07256f69e4d> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-df752480adeca23f8ebea07256f69e4d> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d8c18c6cbd3cdc77d995479fa75507d3> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-d8c18c6cbd3cdc77d995479fa75507d3> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d849a9e85392bb40d8088fb1cdda5000> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-d849a9e85392bb40d8088fb1cdda5000> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b12b31e55f9b2a1601affc48d63fcc48> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-b12b31e55f9b2a1601affc48d63fcc48> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-2e40b01af6770cefcca946dbd3f71168> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-2e40b01af6770cefcca946dbd3f71168> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b03650a5d85dfe337391bd36dfd01b58> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-b03650a5d85dfe337391bd36dfd01b58> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c47b446932bb1123fb48df8d90e2611b> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-c47b446932bb1123fb48df8d90e2611b> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-142a93b76007a7bcfa07df3597487543> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-142a93b76007a7bcfa07df3597487543> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-f547c48e7d9e5ad4a8a7fdb159618adf> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-f547c48e7d9e5ad4a8a7fdb159618adf> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-eb6ffa6349ac084d088cdf38bd8e92d9> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-eb6ffa6349ac084d088cdf38bd8e92d9> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b7cafa630a40712051c6094277e5164a> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-b7cafa630a40712051c6094277e5164a> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e1050462db978a93d696d4f759d3ef0a> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-e1050462db978a93d696d4f759d3ef0a> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-757432e7250866e390426cd5263884b2> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_14> <https://discovery.ucl.ac.uk/id/person/ext-757432e7250866e390426cd5263884b2> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4aa997dcfa1c5a9e110e69e485ff1382> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_15> <https://discovery.ucl.ac.uk/id/person/ext-4aa997dcfa1c5a9e110e69e485ff1382> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-fd88a5ca6c8f78b7f97ade7741be99be> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_16> <https://discovery.ucl.ac.uk/id/person/ext-fd88a5ca6c8f78b7f97ade7741be99be> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3da35cc9dc576ec239b273269baa78ed> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_17> <https://discovery.ucl.ac.uk/id/person/ext-3da35cc9dc576ec239b273269baa78ed> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-5444169bd6794ef48994b0fdcc0620e4> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_18> <https://discovery.ucl.ac.uk/id/person/ext-5444169bd6794ef48994b0fdcc0620e4> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ba713606a129e119f3a94e1173a3686e> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_19> <https://discovery.ucl.ac.uk/id/person/ext-ba713606a129e119f3a94e1173a3686e> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4839f349b03c5fb480e357acb8c1042f> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_20> <https://discovery.ucl.ac.uk/id/person/ext-4839f349b03c5fb480e357acb8c1042f> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-e2f0143dda2b8f623c96814c658cad44> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_21> <https://discovery.ucl.ac.uk/id/person/ext-e2f0143dda2b8f623c96814c658cad44> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-10375c94541b6914f71fc15eb5ca810c> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_22> <https://discovery.ucl.ac.uk/id/person/ext-10375c94541b6914f71fc15eb5ca810c> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-102a36ff7ba00eebe3171fa3060914bb> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_23> <https://discovery.ucl.ac.uk/id/person/ext-102a36ff7ba00eebe3171fa3060914bb> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-7c6d9a1a9c6e6881143125b98cc836dd> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_24> <https://discovery.ucl.ac.uk/id/person/ext-7c6d9a1a9c6e6881143125b98cc836dd> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-08018e96d078f0d9b1b88e038f7a20d7> . <https://discovery.ucl.ac.uk/id/eprint/10110561> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> . <https://discovery.ucl.ac.uk/id/eprint/10110561#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_25> <https://discovery.ucl.ac.uk/id/person/ext-08018e96d078f0d9b1b88e038f7a20d7> . <https://discovery.ucl.ac.uk/id/person/ext-e1050462db978a93d696d4f759d3ef0a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-e1050462db978a93d696d4f759d3ef0a> <http://xmlns.com/foaf/0.1/givenName> "SE"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e1050462db978a93d696d4f759d3ef0a> <http://xmlns.com/foaf/0.1/familyName> "Keuss"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e1050462db978a93d696d4f759d3ef0a> <http://xmlns.com/foaf/0.1/name> "SE Keuss"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b12b31e55f9b2a1601affc48d63fcc48> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-b12b31e55f9b2a1601affc48d63fcc48> <http://xmlns.com/foaf/0.1/givenName> "NJ"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b12b31e55f9b2a1601affc48d63fcc48> <http://xmlns.com/foaf/0.1/familyName> "Ashton"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b12b31e55f9b2a1601affc48d63fcc48> <http://xmlns.com/foaf/0.1/name> "NJ Ashton"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-2e40b01af6770cefcca946dbd3f71168> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-2e40b01af6770cefcca946dbd3f71168> <http://xmlns.com/foaf/0.1/givenName> "JM"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-2e40b01af6770cefcca946dbd3f71168> <http://xmlns.com/foaf/0.1/familyName> "Nicholas"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-2e40b01af6770cefcca946dbd3f71168> <http://xmlns.com/foaf/0.1/name> "JM Nicholas"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-08018e96d078f0d9b1b88e038f7a20d7> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-08018e96d078f0d9b1b88e038f7a20d7> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-08018e96d078f0d9b1b88e038f7a20d7> <http://xmlns.com/foaf/0.1/familyName> "Schott"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-08018e96d078f0d9b1b88e038f7a20d7> <http://xmlns.com/foaf/0.1/name> "J Schott"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d8c18c6cbd3cdc77d995479fa75507d3> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-d8c18c6cbd3cdc77d995479fa75507d3> <http://xmlns.com/foaf/0.1/givenName> "T"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d8c18c6cbd3cdc77d995479fa75507d3> <http://xmlns.com/foaf/0.1/familyName> "Karikari"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d8c18c6cbd3cdc77d995479fa75507d3> <http://xmlns.com/foaf/0.1/name> "T Karikari"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-10375c94541b6914f71fc15eb5ca810c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-10375c94541b6914f71fc15eb5ca810c> <http://xmlns.com/foaf/0.1/givenName> "N"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-10375c94541b6914f71fc15eb5ca810c> <http://xmlns.com/foaf/0.1/familyName> "Fox"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-10375c94541b6914f71fc15eb5ca810c> <http://xmlns.com/foaf/0.1/name> "N Fox"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4839f349b03c5fb480e357acb8c1042f> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-4839f349b03c5fb480e357acb8c1042f> <http://xmlns.com/foaf/0.1/givenName> "E"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4839f349b03c5fb480e357acb8c1042f> <http://xmlns.com/foaf/0.1/familyName> "Portelius"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4839f349b03c5fb480e357acb8c1042f> <http://xmlns.com/foaf/0.1/name> "E Portelius"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3da35cc9dc576ec239b273269baa78ed> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-3da35cc9dc576ec239b273269baa78ed> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3da35cc9dc576ec239b273269baa78ed> <http://xmlns.com/foaf/0.1/familyName> "Barnes"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3da35cc9dc576ec239b273269baa78ed> <http://xmlns.com/foaf/0.1/name> "A Barnes"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4f7de2f74386cfdfc2bd124acfb498c5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-4f7de2f74386cfdfc2bd124acfb498c5> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4f7de2f74386cfdfc2bd124acfb498c5> <http://xmlns.com/foaf/0.1/familyName> "Keshavan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4f7de2f74386cfdfc2bd124acfb498c5> <http://xmlns.com/foaf/0.1/name> "A Keshavan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b03650a5d85dfe337391bd36dfd01b58> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-b03650a5d85dfe337391bd36dfd01b58> <http://xmlns.com/foaf/0.1/givenName> "D"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b03650a5d85dfe337391bd36dfd01b58> <http://xmlns.com/foaf/0.1/familyName> "Cash"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b03650a5d85dfe337391bd36dfd01b58> <http://xmlns.com/foaf/0.1/name> "D Cash"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-757432e7250866e390426cd5263884b2> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-757432e7250866e390426cd5263884b2> <http://xmlns.com/foaf/0.1/givenName> "SN"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-757432e7250866e390426cd5263884b2> <http://xmlns.com/foaf/0.1/familyName> "James"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-757432e7250866e390426cd5263884b2> <http://xmlns.com/foaf/0.1/name> "SN James"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e2f0143dda2b8f623c96814c658cad44> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-e2f0143dda2b8f623c96814c658cad44> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e2f0143dda2b8f623c96814c658cad44> <http://xmlns.com/foaf/0.1/familyName> "Richards"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-e2f0143dda2b8f623c96814c658cad44> <http://xmlns.com/foaf/0.1/name> "M Richards"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f547c48e7d9e5ad4a8a7fdb159618adf> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-f547c48e7d9e5ad4a8a7fdb159618adf> <http://xmlns.com/foaf/0.1/givenName> "TD"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f547c48e7d9e5ad4a8a7fdb159618adf> <http://xmlns.com/foaf/0.1/familyName> "Parker"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-f547c48e7d9e5ad4a8a7fdb159618adf> <http://xmlns.com/foaf/0.1/name> "TD Parker"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-eb6ffa6349ac084d088cdf38bd8e92d9> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-eb6ffa6349ac084d088cdf38bd8e92d9> <http://xmlns.com/foaf/0.1/givenName> "K"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-eb6ffa6349ac084d088cdf38bd8e92d9> <http://xmlns.com/foaf/0.1/familyName> "Lu"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-eb6ffa6349ac084d088cdf38bd8e92d9> <http://xmlns.com/foaf/0.1/name> "K Lu"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-fd88a5ca6c8f78b7f97ade7741be99be> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-fd88a5ca6c8f78b7f97ade7741be99be> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-fd88a5ca6c8f78b7f97ade7741be99be> <http://xmlns.com/foaf/0.1/familyName> "Wong"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-fd88a5ca6c8f78b7f97ade7741be99be> <http://xmlns.com/foaf/0.1/name> "A Wong"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b7cafa630a40712051c6094277e5164a> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-b7cafa630a40712051c6094277e5164a> <http://xmlns.com/foaf/0.1/givenName> "SM"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b7cafa630a40712051c6094277e5164a> <http://xmlns.com/foaf/0.1/familyName> "Buchanan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-b7cafa630a40712051c6094277e5164a> <http://xmlns.com/foaf/0.1/name> "SM Buchanan"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-c47b446932bb1123fb48df8d90e2611b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-c47b446932bb1123fb48df8d90e2611b> <http://xmlns.com/foaf/0.1/givenName> "W"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-c47b446932bb1123fb48df8d90e2611b> <http://xmlns.com/foaf/0.1/familyName> "Coath"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-c47b446932bb1123fb48df8d90e2611b> <http://xmlns.com/foaf/0.1/name> "W Coath"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-142a93b76007a7bcfa07df3597487543> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-142a93b76007a7bcfa07df3597487543> <http://xmlns.com/foaf/0.1/givenName> "CA"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-142a93b76007a7bcfa07df3597487543> <http://xmlns.com/foaf/0.1/familyName> "Lane"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-142a93b76007a7bcfa07df3597487543> <http://xmlns.com/foaf/0.1/name> "CA Lane"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d849a9e85392bb40d8088fb1cdda5000> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-d849a9e85392bb40d8088fb1cdda5000> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d849a9e85392bb40d8088fb1cdda5000> <http://xmlns.com/foaf/0.1/familyName> "Lantero Rodriguez"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-d849a9e85392bb40d8088fb1cdda5000> <http://xmlns.com/foaf/0.1/name> "J Lantero Rodriguez"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-7c6d9a1a9c6e6881143125b98cc836dd> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-7c6d9a1a9c6e6881143125b98cc836dd> <http://xmlns.com/foaf/0.1/givenName> "K"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-7c6d9a1a9c6e6881143125b98cc836dd> <http://xmlns.com/foaf/0.1/familyName> "Blennow"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-7c6d9a1a9c6e6881143125b98cc836dd> <http://xmlns.com/foaf/0.1/name> "K Blennow"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ba713606a129e119f3a94e1173a3686e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-ba713606a129e119f3a94e1173a3686e> <http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ba713606a129e119f3a94e1173a3686e> <http://xmlns.com/foaf/0.1/familyName> "Heslegrave"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-ba713606a129e119f3a94e1173a3686e> <http://xmlns.com/foaf/0.1/name> "A Heslegrave"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-102a36ff7ba00eebe3171fa3060914bb> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-102a36ff7ba00eebe3171fa3060914bb> <http://xmlns.com/foaf/0.1/givenName> "H"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-102a36ff7ba00eebe3171fa3060914bb> <http://xmlns.com/foaf/0.1/familyName> "Zetterberg"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-102a36ff7ba00eebe3171fa3060914bb> <http://xmlns.com/foaf/0.1/name> "H Zetterberg"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4aa997dcfa1c5a9e110e69e485ff1382> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-4aa997dcfa1c5a9e110e69e485ff1382> <http://xmlns.com/foaf/0.1/givenName> "H"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4aa997dcfa1c5a9e110e69e485ff1382> <http://xmlns.com/foaf/0.1/familyName> "Murray Smith"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4aa997dcfa1c5a9e110e69e485ff1382> <http://xmlns.com/foaf/0.1/name> "H Murray Smith"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5444169bd6794ef48994b0fdcc0620e4> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-5444169bd6794ef48994b0fdcc0620e4> <http://xmlns.com/foaf/0.1/givenName> "JC"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5444169bd6794ef48994b0fdcc0620e4> <http://xmlns.com/foaf/0.1/familyName> "Dickson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5444169bd6794ef48994b0fdcc0620e4> <http://xmlns.com/foaf/0.1/name> "JC Dickson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-df752480adeca23f8ebea07256f69e4d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-df752480adeca23f8ebea07256f69e4d> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> . 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