<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> .
<> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10109124> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/title> "Gastrointestinal bleeding risk with rivaroxaban vs aspirin in atrial fibrillation: a multinational study"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/abstract> "Purpose:\r\nComparative gastrointestinal bleeding (GIB) risk between rivaroxaban and low‐dose aspirin is unknown in patients with atrial fibrillation (AF). This study investigated GIB risk with rivaroxaban vs aspirin among two separate AF cohorts in Hong Kong and the United Kingdom, using a common protocol approach.\r\n\r\nMethods:\r\nThis was a population‐based cohort study using separate data from the Clinical Data Analysis and Reporting System (CDARS) of the Hong Kong Hospital Authority (2010‐2018) and The Health Improvement Network (THIN) database in the United Kingdom (2011‐2017). Patients with AF newly prescribed aspirin or rivaroxaban were included. Cox proportional hazards regression was used to compare GIB risks for rivaroxaban vs aspirin, accounting for confounders using propensity score fine stratification approach.\r\n\r\nResults:\r\nIn CDARS, 29 213 patients were included; n = 1052 (rivaroxaban), n = 28 161 (aspirin). Crude GIB event rates per 100 patient‐years in CDARS were 3.0 (aspirin) and 2.6 (rivaroxaban). No difference in GIB risk was observed between rivaroxaban and aspirin overall (HR = 1.04, 95%CI = 0.76‐1.42), and in dose‐stratified analyses (HR = 1.21, 95%CI = 0.84‐1.74 [20 mg/day]; HR = 0.80, 95%CI = 0.44‐1.45 [≤15 mg/day]). In THIN, 11 549 patients were included, n = 3496 (rivaroxaban) and n = 8053 (aspirin). Crude GIB event rates were 1.3 (aspirin) and 2.4 (rivaroxaban) per 100 patient‐years. No difference in GIB risk was observed between rivaroxaban and aspirin overall (HR = 1.40, 95%CI = 1.00‐1.98) and low‐dose rivaroxaban (≤15 mg/day) (HR = 1.00, 95%CI = 0.56‐1.30), but increased GIB risk was observed for rivaroxaban 20 mg/day vs aspirin (HR = 1.57, 95%CI = 1.08‐2.29).\r\n\r\nConclusion:\r\nIn patients with AF, GIB risk was comparable between aspirin and rivaroxaban ≤15 mg/day. GIB risk for rivaroxaban 20 mg/day vs aspirin remains uncertain and warrants further investigation."^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/date> "2020-12" .
<https://discovery.ucl.ac.uk/id/document/1258779> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/volume> "29" .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/issue> "12" .
<https://discovery.ucl.ac.uk/id/org/ext-6bea0d1f0ff0b9fb84fc70d587fb237b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Organization> .
<https://discovery.ucl.ac.uk/id/org/ext-6bea0d1f0ff0b9fb84fc70d587fb237b> <http://xmlns.com/foaf/0.1/name> "John Wiley and Sons"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/publisher> <https://discovery.ucl.ac.uk/id/org/ext-6bea0d1f0ff0b9fb84fc70d587fb237b> .
<https://discovery.ucl.ac.uk/id/publication/ext-f9d5e2681f9f4bb26b8e686e9ea6479b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> .
<https://discovery.ucl.ac.uk/id/publication/ext-f9d5e2681f9f4bb26b8e686e9ea6479b> <http://xmlns.com/foaf/0.1/name> "Pharmacoepidemiology & Drug Safety"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-f9d5e2681f9f4bb26b8e686e9ea6479b> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/published> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-1e4e82116304c2c8527d983b7e709199> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-1e4e82116304c2c8527d983b7e709199> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-1238dedc4c5a51094ecd240bcea4c303> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-1238dedc4c5a51094ecd240bcea4c303> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-ce7819dc193d710a87bd9e2ba251b3b6> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-ce7819dc193d710a87bd9e2ba251b3b6> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-635859384716ce10e29cc244b95fd442> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-635859384716ce10e29cc244b95fd442> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-27cdcf072a87f0226ebfc3f76cede96d> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-27cdcf072a87f0226ebfc3f76cede96d> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a1e4b06c843c411a4814f9289019728d> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-a1e4b06c843c411a4814f9289019728d> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-29c3cd401fbd113aa304c68a41106c3c> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-29c3cd401fbd113aa304c68a41106c3c> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-306734eb416fca59af47f7f4dfddd28e> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-306734eb416fca59af47f7f4dfddd28e> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a193850d7a18782f604eb2b4a0a4f3ad> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-a193850d7a18782f604eb2b4a0a4f3ad> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-d93dd03643a9fceb8dfb2267fe19c433> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-d93dd03643a9fceb8dfb2267fe19c433> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-bb4c623f5999ebce6589dbfab80b6d94> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-bb4c623f5999ebce6589dbfab80b6d94> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b10dc8a5399a6d5ab02b620503d079c1> .
<https://discovery.ucl.ac.uk/id/eprint/10109124> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10109124#authors> .
<https://discovery.ucl.ac.uk/id/eprint/10109124#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-b10dc8a5399a6d5ab02b620503d079c1> .
<https://discovery.ucl.ac.uk/id/person/ext-29c3cd401fbd113aa304c68a41106c3c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-29c3cd401fbd113aa304c68a41106c3c> <http://xmlns.com/foaf/0.1/givenName> "L"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-29c3cd401fbd113aa304c68a41106c3c> <http://xmlns.com/foaf/0.1/familyName> "Wei"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-29c3cd401fbd113aa304c68a41106c3c> <http://xmlns.com/foaf/0.1/name> "L Wei"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-635859384716ce10e29cc244b95fd442> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-635859384716ce10e29cc244b95fd442> <http://xmlns.com/foaf/0.1/givenName> "EW"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-635859384716ce10e29cc244b95fd442> <http://xmlns.com/foaf/0.1/familyName> "Chan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-635859384716ce10e29cc244b95fd442> <http://xmlns.com/foaf/0.1/name> "EW Chan"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ce7819dc193d710a87bd9e2ba251b3b6> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-ce7819dc193d710a87bd9e2ba251b3b6> <http://xmlns.com/foaf/0.1/givenName> "X"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ce7819dc193d710a87bd9e2ba251b3b6> <http://xmlns.com/foaf/0.1/familyName> "Li"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-ce7819dc193d710a87bd9e2ba251b3b6> <http://xmlns.com/foaf/0.1/name> "X Li"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d93dd03643a9fceb8dfb2267fe19c433> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-d93dd03643a9fceb8dfb2267fe19c433> <http://xmlns.com/foaf/0.1/givenName> "JS"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d93dd03643a9fceb8dfb2267fe19c433> <http://xmlns.com/foaf/0.1/familyName> "Bell"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-d93dd03643a9fceb8dfb2267fe19c433> <http://xmlns.com/foaf/0.1/name> "JS Bell"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-306734eb416fca59af47f7f4dfddd28e> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-306734eb416fca59af47f7f4dfddd28e> <http://xmlns.com/foaf/0.1/givenName> "WK"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-306734eb416fca59af47f7f4dfddd28e> <http://xmlns.com/foaf/0.1/familyName> "Leung"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-306734eb416fca59af47f7f4dfddd28e> <http://xmlns.com/foaf/0.1/name> "WK Leung"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1e4e82116304c2c8527d983b7e709199> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-1e4e82116304c2c8527d983b7e709199> <http://xmlns.com/foaf/0.1/givenName> "L"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1e4e82116304c2c8527d983b7e709199> <http://xmlns.com/foaf/0.1/familyName> "Fanning"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1e4e82116304c2c8527d983b7e709199> <http://xmlns.com/foaf/0.1/name> "L Fanning"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1238dedc4c5a51094ecd240bcea4c303> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-1238dedc4c5a51094ecd240bcea4c303> <http://xmlns.com/foaf/0.1/givenName> "ICK"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1238dedc4c5a51094ecd240bcea4c303> <http://xmlns.com/foaf/0.1/familyName> "Wong"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-1238dedc4c5a51094ecd240bcea4c303> <http://xmlns.com/foaf/0.1/name> "ICK Wong"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a193850d7a18782f604eb2b4a0a4f3ad> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-a193850d7a18782f604eb2b4a0a4f3ad> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a193850d7a18782f604eb2b4a0a4f3ad> <http://xmlns.com/foaf/0.1/familyName> "Darzins"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a193850d7a18782f604eb2b4a0a4f3ad> <http://xmlns.com/foaf/0.1/name> "P Darzins"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b10dc8a5399a6d5ab02b620503d079c1> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-b10dc8a5399a6d5ab02b620503d079c1> <http://xmlns.com/foaf/0.1/givenName> "WCY"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b10dc8a5399a6d5ab02b620503d079c1> <http://xmlns.com/foaf/0.1/familyName> "Lau"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-b10dc8a5399a6d5ab02b620503d079c1> <http://xmlns.com/foaf/0.1/name> "WCY Lau"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-27cdcf072a87f0226ebfc3f76cede96d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-27cdcf072a87f0226ebfc3f76cede96d> <http://xmlns.com/foaf/0.1/givenName> "P"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-27cdcf072a87f0226ebfc3f76cede96d> <http://xmlns.com/foaf/0.1/familyName> "Mongkhon"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-27cdcf072a87f0226ebfc3f76cede96d> <http://xmlns.com/foaf/0.1/name> "P Mongkhon"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-bb4c623f5999ebce6589dbfab80b6d94> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-bb4c623f5999ebce6589dbfab80b6d94> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-bb4c623f5999ebce6589dbfab80b6d94> <http://xmlns.com/foaf/0.1/familyName> "Ilomaki"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-bb4c623f5999ebce6589dbfab80b6d94> <http://xmlns.com/foaf/0.1/name> "J Ilomaki"^^<http://www.w3.org/2001/XMLSchema#string> .
<https://discovery.ucl.ac.uk/id/person/ext-a1e4b06c843c411a4814f9289019728d> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> .
<https://discovery.ucl.ac.uk/id/person/ext-a1e4b06c843c411a4814f9289019728d> <http://xmlns.com/foaf/0.1/givenName> "KKC"^^<http://www.w3.org/2001/XMLSchema#string> .
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