TY  - JOUR
KW  - 3D printed drug products
KW  -  Additive manufacturing
KW  -  Digital health
KW  -  Gastrointestinal drug delivery systems
KW  -  Personalized medicines
KW  -  Powder bed fusion
KW  -  Printlets
ID  - discovery10107342
AV  - public
N2  - Pharmaceutical three-dimensional (3D) printing is a modern fabrication process with the potential to create bespoke drug products of virtually any shape and size from a computer-aided design model. Selective laser sintering (SLS) 3D printing combines the benefits of high printing precision and capability, enabling the manufacture of medicines with unique engineering and functional properties. This article reviews the current state-of-the-art in SLS 3D printing, including the main principles underpinning this technology, and highlights the diverse selection of materials and essential parameters that influence printing. The technical challenges and processing conditions are also considered in the context of their effects on the printed product. Finally, the pharmaceutical applications of SLS 3D printing are covered, providing an emphasis on the advantages the technology offers to drug product manufacturing and personalised medicine.
JF  - International Journal of Pharmaceutics
UR  - http://dx.doi.org/10.1016/j.ijpharm.2020.119594
VL  - 586
A1  - Awad, A
A1  - Fina, F
A1  - Goyanes, A
A1  - Gaisford, S
A1  - Basit, AW
SN  - 1873-3476
Y1  - 2020/08/30/
TI  - 3D printing: Principles and pharmaceutical applications of selective laser sintering
N1  - This version is the author accepted manuscript. For information on re-use, please refer to the publisher?s terms and conditions.
ER  -