<> <http://www.w3.org/2000/01/rdf-schema#comment> "The repository administrator has not yet configured an RDF license."^^<http://www.w3.org/2001/XMLSchema#string> . <> <http://xmlns.com/foaf/0.1/primaryTopic> <https://discovery.ucl.ac.uk/id/eprint/10106477> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/AcademicArticle> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Article> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/title> "Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/abstract> "BACKGROUND: Low-dose interleukin-2 (ld-IL-2) enhances regulatory T-cell (Treg) function in auto-inflammatory conditions. Neuroinflammation being a pathogenic feature of amyotrophic lateral sclerosis (ALS), we evaluated the pharmacodynamics and safety of ld-IL-2 in ALS subjects. METHODS: We performed a single centre, parallel three-arm, randomised, double-blind, placebo-controlled study. Eligibility criteria included age < 75 years, disease duration < 5 years, riluzole treatment > 3 months, and a slow vital capacity ≥ 70% of normal. Patients were randomised (1:1:1) to aldesleukin 2 MIU, 1 MIU, or placebo once daily for 5 days every 4 weeks for 3 cycles. Primary outcome was change from baseline in Treg percentage of CD4+ T cells (%Tregs) following a first cycle. Secondary laboratory outcomes included: %Treg and Treg number following repeated cycles, and plasma CCL2 and neurofilament light chain protein (NFL) concentrations as surrogate markers of efficacy. Safety outcomes included motor-function (ALSFRS-R), slow vital capacity (SVC), and adverse event reports. This trial is registered with ClinicalTrials.gov, NCT02059759. FINDINGS: All randomised patients (12 per group), recruited from October 2015 to December 2015, were alive at the end of follow-up and included in the intent-to-treat (ITT) analysis. No drug-related serious adverse event was observed. Non-serious adverse events occurred more frequently with the 1 and 2 MIU IL-2 doses compared to placebo, including injection site reactions and flu-like symptoms. Primary outcome analysis showed a significant increase (p < 0·0001) in %Tregs in the 2 MIU and 1 MIU arms (mean [SD]: 2 MIU: +6·2% [2·2]; 1 MIU: +3·9% [1·2]) as compared to placebo (mean [SD]: -0·49% [1·3]). Effect sizes (ES) were large in treated groups: 2 MIU ES=3·7 (IC95%: 2·3-4·9) and 1 MIU ES=3·5 (IC95%: 2·1-4·6). Secondary outcomes showed a significant increase in %Tregs following repeated cycles (p < 0·0001) as compared to placebo, and a dose-dependent decrease in plasma CCL2 (p = 0·0049). There were no significant differences amongst the three groups on plasma NFL levels. INTERPRETATION: Ld-IL-2 is well tolerated and immunologically effective in subjects with ALS. These results warrant further investigation into their eventual therapeutic impact on slowing ALS disease progression. FUNDING: The French Health Ministry (PHRC-I-14-056), EU H2020 (grant #633413), and the Association pour la Recherche sur la SLA (ARSLA)."^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/date> "2020-07-07" . <https://discovery.ucl.ac.uk/id/document/1151348> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Document> . <https://discovery.ucl.ac.uk/id/publication/ext-972157fb696fdc50b677d6897f098c1b> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://purl.org/ontology/bibo/Collection> . <https://discovery.ucl.ac.uk/id/publication/ext-972157fb696fdc50b677d6897f098c1b> <http://xmlns.com/foaf/0.1/name> "EBioMedicine"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/isPartOf> <https://discovery.ucl.ac.uk/id/publication/ext-972157fb696fdc50b677d6897f098c1b> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/status> <http://purl.org/ontology/bibo/status/forthcoming> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c1fb6f169c79ede4a36d33f4e18b4e3f> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_1> <https://discovery.ucl.ac.uk/id/person/ext-c1fb6f169c79ede4a36d33f4e18b4e3f> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-39aace4c96a5c8648acad921a88fbcd3> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_2> <https://discovery.ucl.ac.uk/id/person/ext-39aace4c96a5c8648acad921a88fbcd3> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-37a53cb3db7db1e98fa941e3a68ceda4> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_3> <https://discovery.ucl.ac.uk/id/person/ext-37a53cb3db7db1e98fa941e3a68ceda4> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-30ed62d287a528d0f379d0b5d5fd3516> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_4> <https://discovery.ucl.ac.uk/id/person/ext-30ed62d287a528d0f379d0b5d5fd3516> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-b45eb7e3f4eec4c36b23fa3ef6e6cd8e> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_5> <https://discovery.ucl.ac.uk/id/person/ext-b45eb7e3f4eec4c36b23fa3ef6e6cd8e> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-3eb5400c05c44729e63cdf748a031e5c> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_6> <https://discovery.ucl.ac.uk/id/person/ext-3eb5400c05c44729e63cdf748a031e5c> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a87b6ba14c1715a4f6dd580eb7ef34fc> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_7> <https://discovery.ucl.ac.uk/id/person/ext-a87b6ba14c1715a4f6dd580eb7ef34fc> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-badb498ee3ee586dc588352acfd9ae4f> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_8> <https://discovery.ucl.ac.uk/id/person/ext-badb498ee3ee586dc588352acfd9ae4f> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-906aec268ff2fd8f424eddb2d6bd3781> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_9> <https://discovery.ucl.ac.uk/id/person/ext-906aec268ff2fd8f424eddb2d6bd3781> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-4c45313fb29bc863b69a8c7ced28fe35> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_10> <https://discovery.ucl.ac.uk/id/person/ext-4c45313fb29bc863b69a8c7ced28fe35> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-82ab72a4c343f259ae44ca21f5ec3283> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_11> <https://discovery.ucl.ac.uk/id/person/ext-82ab72a4c343f259ae44ca21f5ec3283> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-96f09d9dca5a8a362d235d8eb6a6ffa5> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_12> <https://discovery.ucl.ac.uk/id/person/ext-96f09d9dca5a8a362d235d8eb6a6ffa5> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-a4fea0ed74856a90376a6947f6e06318> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_13> <https://discovery.ucl.ac.uk/id/person/ext-a4fea0ed74856a90376a6947f6e06318> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-765907dfdee5bb97d77eb956cb77e1df> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_14> <https://discovery.ucl.ac.uk/id/person/ext-765907dfdee5bb97d77eb956cb77e1df> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-9811c47b90e97a6ad152d62630e96018> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_15> <https://discovery.ucl.ac.uk/id/person/ext-9811c47b90e97a6ad152d62630e96018> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-643da874b34696c7419c61ff1c5e5099> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_16> <https://discovery.ucl.ac.uk/id/person/ext-643da874b34696c7419c61ff1c5e5099> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-894b8cc2d0f11923cdd1c578b86da46a> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_17> <https://discovery.ucl.ac.uk/id/person/ext-894b8cc2d0f11923cdd1c578b86da46a> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-8d319236a58ed0c4737b6a9238cc7131> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_18> <https://discovery.ucl.ac.uk/id/person/ext-8d319236a58ed0c4737b6a9238cc7131> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-c2b23703e35c73451fb2fcafed9b2be9> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_19> <https://discovery.ucl.ac.uk/id/person/ext-c2b23703e35c73451fb2fcafed9b2be9> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-5e74487ff7542dd3a5ac19c72cc1ad26> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_20> <https://discovery.ucl.ac.uk/id/person/ext-5e74487ff7542dd3a5ac19c72cc1ad26> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/dc/terms/creator> <https://discovery.ucl.ac.uk/id/person/ext-2612a0c370765e0614de39d3a0151f67> . <https://discovery.ucl.ac.uk/id/eprint/10106477> <http://purl.org/ontology/bibo/authorList> <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> . <https://discovery.ucl.ac.uk/id/eprint/10106477#authors> <http://www.w3.org/1999/02/22-rdf-syntax-ns#_21> <https://discovery.ucl.ac.uk/id/person/ext-2612a0c370765e0614de39d3a0151f67> . <https://discovery.ucl.ac.uk/id/person/ext-4c45313fb29bc863b69a8c7ced28fe35> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-4c45313fb29bc863b69a8c7ced28fe35> <http://xmlns.com/foaf/0.1/givenName> "U"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4c45313fb29bc863b69a8c7ced28fe35> <http://xmlns.com/foaf/0.1/familyName> "Andreasson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-4c45313fb29bc863b69a8c7ced28fe35> <http://xmlns.com/foaf/0.1/name> "U Andreasson"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-39aace4c96a5c8648acad921a88fbcd3> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-39aace4c96a5c8648acad921a88fbcd3> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-39aace4c96a5c8648acad921a88fbcd3> <http://xmlns.com/foaf/0.1/familyName> "Mickunas"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-39aace4c96a5c8648acad921a88fbcd3> <http://xmlns.com/foaf/0.1/name> "M Mickunas"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-82ab72a4c343f259ae44ca21f5ec3283> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-82ab72a4c343f259ae44ca21f5ec3283> <http://xmlns.com/foaf/0.1/givenName> "J"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-82ab72a4c343f259ae44ca21f5ec3283> <http://xmlns.com/foaf/0.1/familyName> "Kirby"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-82ab72a4c343f259ae44ca21f5ec3283> <http://xmlns.com/foaf/0.1/name> "J Kirby"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-a87b6ba14c1715a4f6dd580eb7ef34fc> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-a87b6ba14c1715a4f6dd580eb7ef34fc> <http://xmlns.com/foaf/0.1/givenName> "R"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-a87b6ba14c1715a4f6dd580eb7ef34fc> <http://xmlns.com/foaf/0.1/familyName> "Juntas-Morales"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-a87b6ba14c1715a4f6dd580eb7ef34fc> <http://xmlns.com/foaf/0.1/name> "R Juntas-Morales"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-96f09d9dca5a8a362d235d8eb6a6ffa5> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-96f09d9dca5a8a362d235d8eb6a6ffa5> <http://xmlns.com/foaf/0.1/givenName> "C"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-96f09d9dca5a8a362d235d8eb6a6ffa5> <http://xmlns.com/foaf/0.1/familyName> "Suehs"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-96f09d9dca5a8a362d235d8eb6a6ffa5> <http://xmlns.com/foaf/0.1/name> "C Suehs"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3eb5400c05c44729e63cdf748a031e5c> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-3eb5400c05c44729e63cdf748a031e5c> <http://xmlns.com/foaf/0.1/givenName> "M"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3eb5400c05c44729e63cdf748a031e5c> <http://xmlns.com/foaf/0.1/familyName> "Locati"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-3eb5400c05c44729e63cdf748a031e5c> <http://xmlns.com/foaf/0.1/name> "M Locati"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-2612a0c370765e0614de39d3a0151f67> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-2612a0c370765e0614de39d3a0151f67> 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<http://xmlns.com/foaf/0.1/givenName> "A"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8d319236a58ed0c4737b6a9238cc7131> <http://xmlns.com/foaf/0.1/familyName> "Al-Chalabi"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-8d319236a58ed0c4737b6a9238cc7131> <http://xmlns.com/foaf/0.1/name> "A Al-Chalabi"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5e74487ff7542dd3a5ac19c72cc1ad26> <http://www.w3.org/1999/02/22-rdf-syntax-ns#type> <http://xmlns.com/foaf/0.1/Person> . <https://discovery.ucl.ac.uk/id/person/ext-5e74487ff7542dd3a5ac19c72cc1ad26> <http://xmlns.com/foaf/0.1/givenName> "T"^^<http://www.w3.org/2001/XMLSchema#string> . <https://discovery.ucl.ac.uk/id/person/ext-5e74487ff7542dd3a5ac19c72cc1ad26> <http://xmlns.com/foaf/0.1/familyName> "Tree"^^<http://www.w3.org/2001/XMLSchema#string> . 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