%0 Journal Article
%A Xiong, X
%A Chua, GT
%A Chi, S
%A Kwan, MYW
%A Wong, WHS
%A Zhou, A
%A Shek, CC
%A Tung, KTS
%A Qin, H
%A Wong, RS
%A Li, X
%A Chen, P
%A Li, S
%A Chui, CS
%A Tso, WWY
%A Ho, MHK
%A Wong, ICK
%A Chan, GCF
%A Lau, YL
%A Wong, KKY
%A Chung, PHY
%A Li, H
%A Tam, PKH
%A Tang, S-T
%A Lp, P
%D 2020
%F discovery:10106177
%J Data Brief
%K COVID-19, Children, Chinese, Cytokines, Immunoglobulin, Lymphocyte subsets
%T Haematological and immunological data of Chinese children infected with coronavirus disease 2019
%U https://discovery.ucl.ac.uk/id/eprint/10106177/
%V 31
%X Haematological and immunological data of children with  COVID-19 infection is lacking. Between 21st January and  20th March 2020, 244 children who were confirmed to have  COVID-19 infection and admitted to the Wuhan Children’s  Hospital, China were retrospectively reviewed. 193 children  were considered as symptomatic, which was defined as having either the presence of clinical symptoms or the presence  of CT thorax abnormalities. Their haematological and immunological profiles, including complete blood counts, lymphocyte subsets (T, B and NK cell counts), immunoglobulin (Ig) profiles (IgG, IgA and IgM) and cytokine profiles  were analysed and compared between the symptomatic and  asymptomatic groups. The median values and the interquartile ranges were calculated. Comparison was made using the  Mann–Whitney U test. Children with symptomatic COVID19 infection had significantly lower haemoglobin levels, but  higher absolute lymphocyte and monocyte counts, IgG and  IgA levels, as well as interleukin 6 (IL-6), IL-10, tumour  necrosis factor alpha and interferon gamma levels. The obtained data will be utilized for further studies in comparing  children and adults with COVID-19 infections in other parts  of the world and with different severity .
%Z This is an open access article under the CC BY license.  (http://creativecommons.org/licenses/by/4.0/)