eprintid: 10102896
rev_number: 25
eprint_status: archive
userid: 608
dir: disk0/10/10/28/96
datestamp: 2021-06-04 15:22:17
lastmod: 2021-09-19 22:57:20
status_changed: 2021-06-04 15:22:17
type: proceedings_section
metadata_visibility: show
creators_name: Slator, PJ
creators_name: Ho, A
creators_name: Bakalis, S
creators_name: Jackson, L
creators_name: Chappell, LC
creators_name: Alexander, DC
creators_name: Hajnal, JV
creators_name: Rutherford, M
creators_name: Hutter, J
title: Anisotropy in the Human Placenta in Pregnancies Complicated by Fetal Growth Restriction
ispublished: pub
divisions: UCL
divisions: B04
divisions: C05
divisions: F48
note: © The Author(s) 2021
Open Access
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abstract: The placenta has a unique structure, which enables the transfer of oxygen and nutrients from the mother to the developing fetus. Abnormalities in placental structure are associated with major complications of pregnancy; for instance, changes in the complex branching structures of fetal villous trees are associated with fetal growth restriction. Diffusion MRI has the potential to measure such fine placental microstructural details. Here, we present in-vivo placental diffusion MRI scans from controls and pregnancies complicated by fetal growth restriction. We find that after 30 weeks’ gestation fractional anisotropy is significantly higher in placentas associated with growth restricted pregnancies. This shows the potential of diffusion MRI derived measures of anisotropy for assessing placental function during pregnancy.
date: 2021-02-11
date_type: published
publisher: Springer
official_url: https://doi.org/10.1007/978-3-030-56215-1_13
oa_status: green
full_text_type: pub
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1793960
doi: 10.1007/978-3-030-56215-1_13
isbn_13: 9783030562144
lyricists_name: Alexander, Daniel
lyricists_name: Slator, Patrick
lyricists_id: DALEX06
lyricists_id: PJSLA44
actors_name: Dewerpe, Marie
actors_id: MDDEW97
actors_role: owner
full_text_status: public
publication: Mathematics and Visualization
place_of_pub: Cham, Switzerland
pagerange: 263-276
issn: 2197-666X
book_title: Anisotropy Across Fields and Scales. Mathematics and Visualization
editors_name: Özarslan, E
editors_name: Schultz, T
editors_name: Zhang, E
editors_name: Fuster, A
citation:        Slator, PJ;    Ho, A;    Bakalis, S;    Jackson, L;    Chappell, LC;    Alexander, DC;    Hajnal, JV;         ... Hutter, J; + view all <#>        Slator, PJ;  Ho, A;  Bakalis, S;  Jackson, L;  Chappell, LC;  Alexander, DC;  Hajnal, JV;  Rutherford, M;  Hutter, J;   - view fewer <#>    (2021)    Anisotropy in the Human Placenta in Pregnancies Complicated by Fetal Growth Restriction.                     In: Özarslan, E and Schultz, T and Zhang, E and Fuster, A, (eds.) Anisotropy Across Fields and Scales. Mathematics and Visualization.  (pp. pp. 263-276).  Springer: Cham, Switzerland.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10102896/1/Slator_2021_Chapter_AnisotropyInTheHumanPlacentaIn.pdf