TY  - GEN
A1  - Slator, PJ
A1  - Ho, A
A1  - Bakalis, S
A1  - Jackson, L
A1  - Chappell, LC
A1  - Alexander, DC
A1  - Hajnal, JV
A1  - Rutherford, M
A1  - Hutter, J
CY  - Cham, Switzerland
SN  - 2197-666X
PB  - Springer
UR  - https://doi.org/10.1007/978-3-030-56215-1_13
ID  - discovery10102896
N2  - The placenta has a unique structure, which enables the transfer of oxygen and nutrients from the mother to the developing fetus. Abnormalities in placental structure are associated with major complications of pregnancy; for instance, changes in the complex branching structures of fetal villous trees are associated with fetal growth restriction. Diffusion MRI has the potential to measure such fine placental microstructural details. Here, we present in-vivo placental diffusion MRI scans from controls and pregnancies complicated by fetal growth restriction. We find that after 30 weeks? gestation fractional anisotropy is significantly higher in placentas associated with growth restricted pregnancies. This shows the potential of diffusion MRI derived measures of anisotropy for assessing placental function during pregnancy.
N1  - © The Author(s) 2021
Open Access
This chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence and indicate if changes were made.

The images or other third party material in this chapter are included in the chapter's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the chapter's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
EP  - 276
AV  - public
SP  - 263
Y1  - 2021/02/11/
TI  - Anisotropy in the Human Placenta in Pregnancies Complicated by Fetal Growth Restriction
ER  -