eprintid: 10095207 rev_number: 15 eprint_status: archive userid: 608 dir: disk0/10/09/52/07 datestamp: 2020-04-23 13:48:59 lastmod: 2021-09-20 22:33:00 status_changed: 2020-04-23 13:48:59 type: article metadata_visibility: show creators_name: Kitzman, H creators_name: Olds, DL creators_name: Knudtson, MD creators_name: Cole, R creators_name: Anson, E creators_name: Smith, JA creators_name: Fishbein, D creators_name: DiClemente, R creators_name: Wingood, G creators_name: Caliendo, AM creators_name: Hopfer, C creators_name: Miller, T creators_name: Conti, G title: Prenatal and Infancy Nurse Home Visiting and 18-Year Outcomes of a Randomized Trial ispublished: pub divisions: UCL divisions: B03 divisions: C03 divisions: F24 note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: OBJECTIVES: Given earlier effects found in randomized clinical trials of the Nurse-Family Partnership, we examined whether this program would improve 18-year-old first-born youths' cognition, academic achievement, and behavior and whether effects on cognitive-related outcomes would be greater for youth born to mothers with limited psychological resources (LPR) and on arrests and convictions among females. METHODS: We enrolled 742 pregnant, low-income women with no previous live births and randomly assigned them to receive either free transportation for prenatal care plus child development screening and referral (control; n = 514) or prenatal and infant home nurse visit (NV) plus transportation and screening (n = 228). Assessments were completed on 629 18-year-old first-born offspring to evaluate these primary outcomes: (1) cognitive-related abilities (nonverbal intelligence, receptive language, and math achievement) and (2) behavioral health (internalizing behavioral problems, substance use and abuse, sexually transmitted infections, HIV risk, arrests, convictions, and gang membership). RESULTS: Compared with control-group counterparts, NV youth born to mothers with LPR had better receptive language (effect size = 0.24; 95% confidence interval [CI]: 0.00 to 0.47; P = .05), math achievement (effect size = 0.38; 95% CI: 0.14 to 0.61; P = .002), and a number of secondary cognitive-related outcomes. NV females, as a trend, had fewer convictions (incidence ratio = 0.47; 95% CI: 0.20 to 1.11; P = .08). There were no intervention effects on other behaviors. CONCLUSIONS: The program improved the cognitive-related skills of 18-year-olds born to mothers with LPR and, as a trend, reduced female convictions but produced no other effects on youth behavioral health. date: 2019-12 date_type: published publisher: AMER ACAD PEDIATRICS official_url: https://doi.org/10.1542/peds.2018-3876 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1741181 doi: 10.1542/peds.2018-3876 lyricists_name: Conti, Gabriella lyricists_id: GCONT23 actors_name: Conti, Gabriella actors_id: GCONT23 actors_role: owner full_text_status: public publication: Pediatrics volume: 144 number: 6 article_number: e20183876 pages: 13 citation: Kitzman, H; Olds, DL; Knudtson, MD; Cole, R; Anson, E; Smith, JA; Fishbein, D; ... Conti, G; + view all <#> Kitzman, H; Olds, DL; Knudtson, MD; Cole, R; Anson, E; Smith, JA; Fishbein, D; DiClemente, R; Wingood, G; Caliendo, AM; Hopfer, C; Miller, T; Conti, G; - view fewer <#> (2019) Prenatal and Infancy Nurse Home Visiting and 18-Year Outcomes of a Randomized Trial. Pediatrics , 144 (6) , Article e20183876. 10.1542/peds.2018-3876 <https://doi.org/10.1542/peds.2018-3876>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10095207/1/Kitzman_Olds_Knudtson_etal_Peds_R2.2019_Prenatal-Infancy%20Nurse%20Home%20Visiting%20and%2018-Year%20Outcomes%20of%20a%20Randomized%20Trial.pdf