TY - JOUR PB - ELSEVIER GMBH N2 - Photoacoustic imaging (PAI) is an emerging biomedical imaging modality that is based on optical absorption contrast, capable of revealing distinct spectroscopic signatures of tissue at high spatial resolution and large imaging depths. However, clinical applications of conventional non-invasive PAI systems have been restricted to examinations of tissues at depths less than a few cm due to strong light attenuation. Minimally invasive photoacoustic imaging (miPAI) has greatly extended the landscape of PAI by delivering excitation light within tissue through miniature fibre-optic probes. In the past decade, various miPAI systems have been developed with demonstrated applicability in several clinical fields. In this article, we present an overview of the current status of miPAI and our thoughts on future perspectives. Y1 - 2019/12// UR - https://doi.org/10.1016/j.pacs.2019.100146 N1 - © 2019 The Authors. Published by Elsevier GmbH. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). JF - Photoacoustics TI - Minimally invasive photoacoustic imaging: Current status and future perspectives AV - public ID - discovery10093963 VL - 16 KW - Photoacoustic imaging KW - Photoacoustic computed tomography KW - Photoacoustic microscopy KW - Multi-modal imaging KW - Minimally invasive procedures KW - Interventional photoacoustic imaging KW - Photoacoustic endoscopy EP - 18 SN - 2213-5979 A1 - Zhao, T A1 - Desjardins, AE A1 - Ourselin, S A1 - Vercauteren, T A1 - Xia, W ER -