TY - JOUR N1 - This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. VL - 16 KW - Neurons KW - Simulation and modeling KW - Network analysis KW - Neural networks KW - Biophysics KW - Biophysical simulations KW - Synapses KW - Neuronal morphology JF - PLOS Computational Biology A1 - Dai, K A1 - Hernando, J A1 - Billeh, YN A1 - Gratiy, SL A1 - Planas, J A1 - Davison, AP A1 - Dura-Bernal, S A1 - Gleeson, P A1 - Devresse, A A1 - Dichter, BK A1 - Gevaert, M A1 - King, JG A1 - Van Geit, WAH A1 - Povolotsky, AV A1 - Muller, E A1 - Courcol, J-D A1 - Arkhipov, A TI - The SONATA data format for efficient description of large-scale network models Y1 - 2020/02/24/ AV - public IS - 2 N2 - Increasing availability of comprehensive experimental datasets and of high-performance computing resources are driving rapid growth in scale, complexity, and biological realism of computational models in neuroscience. To support construction and simulation, as well as sharing of such large-scale models, a broadly applicable, flexible, and high-performance data format is necessary. To address this need, we have developed the Scalable Open Network Architecture TemplAte (SONATA) data format. It is designed for memory and computational efficiency and works across multiple platforms. The format represents neuronal circuits and simulation inputs and outputs via standardized files and provides much flexibility for adding new conventions or extensions. SONATA is used in multiple modeling and visualization tools, and we also provide reference Application Programming Interfaces and model examples to catalyze further adoption. SONATA format is free and open for the community to use and build upon with the goal of enabling efficient model building, sharing, and reproducibility. UR - https://doi.org/10.1371/journal.pcbi.1007696 ID - discovery10093154 ER -