eprintid: 10092539 rev_number: 24 eprint_status: archive userid: 608 dir: disk0/10/09/25/39 datestamp: 2020-03-02 15:38:52 lastmod: 2021-12-13 01:48:17 status_changed: 2020-03-02 15:38:52 type: article metadata_visibility: show creators_name: Secinaro, A creators_name: Curione, D creators_name: Mortensen, KH creators_name: Santangelo, TP creators_name: Ciancarella, P creators_name: Napolitano, C creators_name: Del Pasqua, A creators_name: Taylor, AM creators_name: Ciliberti, P title: Dual-source computed tomography coronary artery imaging in children ispublished: pub divisions: UCL divisions: B02 divisions: D14 divisions: GA1 note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. abstract: Computed tomography (CT) has a well-established diagnostic role in the assessment of coronary arteries in adults. However, its application in a pediatric setting is still limited and often impaired by several technical issues, such as high heart rates, poor patient cooperation, and radiation dose exposure. Nonetheless, CT is becoming crucial in the noninvasive approach of children affected by coronary abnormalities and congenital heart disease. In some circumstances, CT might be preferred to other noninvasive techniques such as echocardiography and MRI for its lack of acoustic window influence, shorter acquisition time, and high spatial resolution. The introduction of dual-source CT has expanded the role of CT in the evaluation of pediatric cardiovascular anatomy and pathology. Furthermore, technical advances in the optimization of low-dose protocols represent an attractive innovation. Dual-source CT can play a key role in several clinical settings in children, namely in the evaluation of children with suspected congenital coronary artery anomalies, both isolated and in association with congenital heart disease. Moreover, it can be used to assess acquired coronary artery abnormalities, as in children with Kawasaki disease and after surgical manipulation, especially in case of transposition of the great arteries treated with arterial switch operation and in case of coronary re-implantation. date: 2019-08-22 date_type: published publisher: SPRINGER official_url: http://dx.doi.org/10.1007/s00247-019-04494-2 oa_status: green full_text_type: other language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1685092 doi: 10.1007/s00247-019-04494-2 lyricists_name: Taylor, Andrew lyricists_id: AMTAY28 actors_name: Dewerpe, Marie actors_id: MDDEW97 actors_role: owner full_text_status: public publication: Pediatric Radiology volume: 49 number: 13 pagerange: 1823-1839 pages: 17 citation: Secinaro, A; Curione, D; Mortensen, KH; Santangelo, TP; Ciancarella, P; Napolitano, C; Del Pasqua, A; ... Ciliberti, P; + view all <#> Secinaro, A; Curione, D; Mortensen, KH; Santangelo, TP; Ciancarella, P; Napolitano, C; Del Pasqua, A; Taylor, AM; Ciliberti, P; - view fewer <#> (2019) Dual-source computed tomography coronary artery imaging in children. Pediatric Radiology , 49 (13) pp. 1823-1839. 10.1007/s00247-019-04494-2 <https://doi.org/10.1007/s00247-019-04494-2>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10092539/3/Taylor_Dual-source%20computed%20tomography%20coronary%20artery%20imaging%20in%20children.pdf