@article{discovery10090983, pages = {121--129}, journal = {Ophthalmologica}, note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.}, publisher = {KARGER}, year = {2019}, volume = {241}, number = {3}, title = {Stereoscopic Vision in Macular Telangiectasia Type 2}, url = {https://doi.org/10.1159/000492134}, author = {Mueller, S and Heeren, TFC and Nadal, J and Issa, PC and Herrmann, P and Holz, FG and Wabbels, BK}, abstract = {PURPOSE: To investigate stereoscopic vision in patients with macular telangiectasia type 2 and correlate a paracentral sensitivity loss to reduced stereoscopic function. METHODS: In a prospective single-center study, 50 patients with macular telangiectasia type 2 and 25 age-matched controls were investigated. Stereoscopic function was evaluated with Lang I, Titmus and TNO-test. Sensitivity of the central 16o was tested using fundus-controlled perimetry (microperimetry). Functional loss was quantified as depth, size and localization of scotomata. RESULTS: Both Titmus and TNO-test revealed significantly reduced stereoscopic vision in patients compared to controls (both, p{\ensuremath{<}}0.0001). This applied even to patients with only relative or monocular paracentral scotomata. A strong correlation was observed for reduced stereoscopic vision with horizontal scotoma size and with the distance of scotomata from the foveal center. CONCLUSIONS: The results indicate that stereoscopic vision is impaired early in patients with MacTel type 2. A paracentral sensitivity loss, even if mild and limited to one eye, may considerably interfere with stereoscopic function despite normal visual acuity. Projection of paracentral scotomata within the patient`s central visual field plays an important role in stereoscopic vision and should be considered when interpreting stereoscopic test results.} }