@article{discovery10090983,
           pages = {121--129},
         journal = {Ophthalmologica},
            note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.},
       publisher = {KARGER},
            year = {2019},
          volume = {241},
          number = {3},
           title = {Stereoscopic Vision in Macular Telangiectasia Type 2},
             url = {https://doi.org/10.1159/000492134},
          author = {Mueller, S and Heeren, TFC and Nadal, J and Issa, PC and Herrmann, P and Holz, FG and Wabbels, BK},
        abstract = {PURPOSE: To investigate stereoscopic vision in patients with macular telangiectasia
type 2 and correlate a paracentral sensitivity loss to reduced stereoscopic function.
METHODS: In a prospective single-center study, 50 patients with macular
telangiectasia type 2 and 25 age-matched controls were investigated. Stereoscopic
function was evaluated with Lang I, Titmus and TNO-test. Sensitivity of the central
16o was tested using fundus-controlled perimetry (microperimetry). Functional loss
was quantified as depth, size and localization of scotomata.
RESULTS: Both Titmus and TNO-test revealed significantly reduced stereoscopic
vision in patients compared to controls (both, p{\ensuremath{<}}0.0001). This applied even to
patients with only relative or monocular paracentral scotomata. A strong correlation
was observed for reduced stereoscopic vision with horizontal scotoma size and with
the distance of scotomata from the foveal center.
CONCLUSIONS: The results indicate that stereoscopic vision is impaired early in
patients with MacTel type 2. A paracentral sensitivity loss, even if mild and limited to
one eye, may considerably interfere with stereoscopic function despite normal visual
acuity. Projection of paracentral scotomata within the patient`s central visual field
plays an important role in stereoscopic vision and should be considered when
interpreting stereoscopic test results.}
}