@article{discovery10090479,
         journal = {Neurorehabilitation and Neural Repair},
           title = {A Stroke Recovery Trial Development Framework: Consensus-Based Core Recommendations from the Second Stroke Recovery and Rehabilitation Roundtable},
           pages = {959--969},
          volume = {33},
            note = {This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.},
       publisher = {SAGE PUBLICATIONS INC},
          number = {11},
            year = {2019},
           month = {November},
            issn = {1552-6844},
             url = {https://doi.org/10.1177/1545968319888642},
          author = {Bernhardt, J and Hayward, KS and Dancause, N and Lannin, NA and Ward, NS and Nudo, RJ and Farrin, A and Churilov, L and Boyd, LA and Jones, TA and Carmichael, ST and Corbett, D and Cramer, SC},
        abstract = {A major goal of the Stroke Recovery and Rehabilitation Roundtable (SRRR) is to accelerate development of effective treatments to enhance stroke recovery beyond that expected to occur spontaneously or with current approaches. In this paper, we describe key issues for the next generation of stroke recovery treatment trials and present the Stroke Recovery and Rehabilitation Roundtable Trials Development Framework (SRRR-TDF). An exemplar (an upper limb recovery trial) is presented to demonstrate the utility of this framework to guide the GO, NO-GO decision-making process in trial development.},
        keywords = {Stroke, rehabilitation, recovery, consensus, trial design, GO NO-GO}
}