eprintid: 10088501
rev_number: 28
eprint_status: archive
userid: 608
dir: disk0/10/08/85/01
datestamp: 2020-01-06 13:18:58
lastmod: 2022-01-25 23:30:06
status_changed: 2020-01-06 13:18:58
type: proceedings_section
metadata_visibility: show
creators_name: De Blasi, B
creators_name: Menegaz, G
creators_name: Barnes, A
creators_name: De Vita, E
creators_name: Storti, SF
creators_name: Galazzo, IB
creators_name: Koepp, M
title: Perfusion-based brain connectivity: PASL vs PCASL
ispublished: pub
divisions: UCL
divisions: B02
divisions: C07
divisions: D07
divisions: F81
divisions: C10
divisions: D17
divisions: B04
divisions: C05
divisions: F43
keywords: ASL, PASL, pCASL, CBF, Functional Connectivity
note: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
abstract: Arterial Spin Labelling (ASL) is a magnetic resonance imaging technique which provides a more direct measure of neural activity as compared to blood-oxygenation-level-dependent (BOLD) contrast. While it has been used for years for perfusion quantification, ASL has recently been adopted for functional connectivity (FC) analyses. However, the impact of the different ASL schemes on connectivity estimates remains to be fully investigated. In this work, pulsed and pseudo continuous ASL (PASL/pCASL) were compared in terms of cerebral blood flow (CBF) and FC measures. In line with literature, higher CBF and increased spatial signal-to-noise ratio were reported for pCASL, as compared to PASL. In terms of FC, pCASL was able to more reliably recover the main networks and showed higher correlations between brain areas. These preliminary results suggest pCASL to provide reliable and stable results, not only for CBF estimation but also for FC analyses.
date: 2019-11-18
date_type: published
publisher: IEEE
official_url: https://doi.org/10.23919/EUSIPCO.2019.8903183
oa_status: green
full_text_type: other
language: eng
primo: open
primo_central: open_green
verified: verified_manual
elements_id: 1732683
doi: 10.23919/EUSIPCO.2019.8903183
isbn_13: 9789082797039
lyricists_name: Barnes, Anna
lyricists_name: De Blasi, Bianca
lyricists_name: Koepp, Matthias
lyricists_id: APBAR63
lyricists_id: BDEBL81
lyricists_id: MJKOE13
actors_name: De Blasi, Bianca
actors_id: BDEBL81
actors_role: owner
full_text_status: public
publication: European Signal Processing Conference
volume: 2019-S
place_of_pub: A Coruna, Spain, Spain
event_title: 2019 27th European Signal Processing Conference (EUSIPCO)
issn: 2219-5491
book_title: Proceedings of the  2019 27th European Signal Processing Conference (EUSIPCO)
citation:        De Blasi, B;    Menegaz, G;    Barnes, A;    De Vita, E;    Storti, SF;    Galazzo, IB;    Koepp, M;      (2019)    Perfusion-based brain connectivity: PASL vs PCASL.                     In:  Proceedings of the 2019 27th European Signal Processing Conference (EUSIPCO).    IEEE: A Coruna, Spain, Spain.       Green open access   
 
document_url: https://discovery.ucl.ac.uk/id/eprint/10088501/1/EUSIPCO2019_ASL_Reviewed-v2-Checked_PID5988075.pdf