eprintid: 10088077 rev_number: 16 eprint_status: archive userid: 608 dir: disk0/10/08/80/77 datestamp: 2019-12-17 16:06:01 lastmod: 2021-09-26 23:14:50 status_changed: 2019-12-17 16:06:01 type: article metadata_visibility: show creators_name: Hassiotis, A creators_name: Brown, E creators_name: Harris, J creators_name: Helm, D creators_name: Munir, K creators_name: Salvador-Carulla, L creators_name: Bertelli, M creators_name: Baghdadli, A creators_name: Wieland, J creators_name: Novell-Alsina, R creators_name: Cid, J creators_name: Vergés, L creators_name: Martínez-Leal, R creators_name: Mutluer, T creators_name: Ismayilov, F creators_name: Emerson, E title: Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort ispublished: pub divisions: UCL divisions: B02 divisions: C07 divisions: D79 keywords: Borderline, Intellectual, Adversity, Mental wellbeing, Childhood note: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. abstract: BACKGROUND To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. METHODS We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity. RESULTS Children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104–0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity. CONCLUSIONS The relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group. date: 2019-12-05 date_type: published official_url: https://doi.org/10.1186/s12888-019-2376-0 oa_status: green full_text_type: pub language: eng primo: open primo_central: open_green verified: verified_manual elements_id: 1731482 doi: 10.1186/s12888-019-2376-0 pii: 10.1186/s12888-019-2376-0 lyricists_name: Hassiotis, Angela lyricists_id: AHASS94 actors_name: Flynn, Bernadette actors_id: BFFLY94 actors_role: owner full_text_status: public publication: BMC Psychiatry volume: 19 article_number: 387 event_location: England citation: Hassiotis, A; Brown, E; Harris, J; Helm, D; Munir, K; Salvador-Carulla, L; Bertelli, M; ... Emerson, E; + view all <#> Hassiotis, A; Brown, E; Harris, J; Helm, D; Munir, K; Salvador-Carulla, L; Bertelli, M; Baghdadli, A; Wieland, J; Novell-Alsina, R; Cid, J; Vergés, L; Martínez-Leal, R; Mutluer, T; Ismayilov, F; Emerson, E; - view fewer <#> (2019) Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort. BMC Psychiatry , 19 , Article 387. 10.1186/s12888-019-2376-0 <https://doi.org/10.1186/s12888-019-2376-0>. Green open access document_url: https://discovery.ucl.ac.uk/id/eprint/10088077/1/s12888-019-2376-0.pdf